2019 American Transplant Congress
Increasing Time-in-Therapeutic Range of Tacrolimus is Associated with Superior Outcomes in Living Kidney Transplants
*Purpose: Tacrolimus-based regimens remain the backbone of maintenance immunosuppressive therapy in kidney transplant, and therapeutic drug monitoring of tacrolimus is necessary due to a narrow…2019 American Transplant Congress
Mathematical Model of Post-Transplant Serum Creatinine
*Purpose: Commonly used equations calculating eGFR are not applicable when serum creatinine (Scr) is rapidly changing such as the post-transplant period. The purpose of this…2019 American Transplant Congress
EBV+ PTLD in the Modern Immunosuppression Era: Role of EBV Serology and DNAemia-Preliminary Data from CTOT-C06
*Purpose: Post-transplant lymphoproliferative disorder (PTLD) remains a serious problem in the pediatric transplant population. The Clinical Trials of Organ Transplantation in Children (CTOT-C)-06 is an…2019 American Transplant Congress
Tacrolimus Concentrations Can Be Reliably Measured in Capillary Microsamples
Oslo University Hospital, Rikshospitalet, Oslo, Norway
*Purpose: Routine therapeutic drug monitoring (TDM) of tacrolimus (Tac) is currently performed in venous bloods samples drawn at the hospital. The novel volumetric absorptive microsampling…2019 American Transplant Congress
Natural Evolution Of Tacrolimus Intra-patient Variability Among Renal Transplant Recipients
University of Cincinnati, Cincinnati, OH
*Purpose: High tacrolimus (TAC) intra-patient variability (IPV) has been correlated with negative outcomes post renal transplant (RT). The natural evolution of TAC IPV remains uncharacterized…2019 American Transplant Congress
Challenges to Inpatient Management Post Abdominal Wall Transplant (AWT) – From App’s Perspective
Duke University hospital, Durham, NC
*Purpose: To highlight the unique features of caring for an AWT recipient and identify areas of improvement for future cases*Methods: AWT is an innovative adjunct…2019 American Transplant Congress
Patient Centered AUC-Monitoring of Tacrolimus Using Capillary Microsampling
Oslo University Hospital, Rikshospitalet, Oslo, Norway
*Purpose: To reduce unwanted side effects of Tacrolimus (Tac), improvement of dosing is warranted. Therapeutic drug monitoring (TDM) of Tac based on trough concentrations (C0)…2019 American Transplant Congress
Pre Transplant Intact FGF 23 Modifies Post-Transplant Improvement in Cognition
*Purpose: Fibroblast growth factor 23 (FGF23) has been associated with cognitive impairment in ESRD. Both FGF23 levels and cognition improve post-kidney transplantation (KT). It is…2019 American Transplant Congress
Significantly High FOXP3 mRNA in the Renal Allograft as a Mechanism of Tolerance Induced by Transient Mixed Chimerism in Non-Human Primates
*Purpose: Treg-rich organized lymphoid structures (TOLS) has been identified in recipients with renal allograft tolerance induced by transient mixed chimerism in non-human primates (NHPs) and…2019 American Transplant Congress
Impact of Clinical Trial Enrollment on Renal Transplant Outcomes
Saint Barnabas Medical Center, Livingston, NJ
*Purpose: The advancement of science and medicine begins with new therapies and techniques arriving through clinical trials. The possibility of improved patient outcomes may also…
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