Articles tagged "Minor histocompatibility antigens"

2017 American Transplant Congress
mTORC1 and 2 Regulate Dendritic Cell (DC) Metabolism and Allostimulatory Function of Donor DCs in Skin Transplantation.
A. Watson,^1,2 H. Dai,^1,3 A. Menk,^4,5 G. Delgoffe,^4,5 A. Thomson.^1,2,3
¹Starzl Transplantation Institute, Univ. of Pittsburgh, Pittsburgh; ²Pathology, Univ. of Pittsburgh, Pittsburgh; ³Surgery, Univ. of Pittsburgh, Pittsburgh; ⁴Immunology, Univ. of Pittsburgh, Pittsburgh; ⁵Cancer Institute, Univ. of Pittsburgh, Pittsburgh
Background/Hypothesis: The mechanistic target of rapamycin (mTOR) is a kinase that functions in two complexes: rapamycin (RAPA)-sensitive mTORC1 and RAPA-insensitive mTORC2. These complexes play critical…