ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Minor histocompatibility antigens"

  • 2020 American Transplant Congress

    Donor and Recipient Sex Affect Transplant Outcomes in an Age-Specific Fashion

    R. Maenosono1, Y. Nian1, J. Iske1, Y. Liu1, H. Azuma2, E. Milford3, S. G. Tullius1

    1Division of Transplant Surgery, Brigham and Women's Hospital, Boston, MA, 2Urology, Osaka Medical College, Osaka, Japan, 3Renal Division, Brigham and Women's Hospital, Boston, MA

    *Purpose: Donor and recipient sex impact transplant outcomes. The biology of sex-specific alloimmune responses has not been studied in detail.*Methods: Using clinical data from more…
  • 2020 American Transplant Congress

    A Mouse Model of Non-MHC Mismatches Recapitulates Chronic Allograft Dysfunction and I-IFTA

    V. Pavlov1, F. Garzon1, R. Haroon Al Rasheed2, K. Banu1, F. ElSalem1, L. Li1, E. Cody1, M. Planoutene1, N. Chun1, Z. Zhang1, J. Leventhal1, B. Murphy1, P. Heeger1, M. C. Menon1

    1Medicine, Mount Sinai School of Medicine, New York, NY, 2Pathology, Mount Sinai School of Medicine, New York, NY

    *Purpose: Fibrotic and atrophic changes or IF/TA is an important cause of graft loss. We reported that genome-wide donor-recipient non-HLA mismatches independently correlate with Banff…
  • 2019 American Transplant Congress

    Autoantibody Production Significantly Decreased with APRIL/BLyS Blockade in Murine Chronic Rejection Kidney Transplant Model

    N. Bath, X. Ding, B. Verhoven, S. Reese, N. Wilson, A. Sukhwal, R. Redfield III

    University of Wisconsin, Madison, WI

    *Purpose: Chronic antibody mediated rejection (cAMR) remains a significant barrier to achieving long-term graft survival in kidney transplantation. Alloantibody production from B lymphocytes and plasma…
  • 2019 American Transplant Congress

    Analysis and Regulation of Immune Reaction in the Transplantation from MHC Homozygous Donors to Heterozygous Recipients with Minor Antigen Mismatches

    T. Murata, H. Wada, R. Otsuka, H. Tsuji, A. Sasaki, M. Baghdadi, K. Seino

    Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan

    *Purpose: Induced pluripotent stem cells (iPSCs) is expected to be the source of therapeutic cells in the regenerative medicine. Autologous derivation of iPSCs is the…
  • 2017 American Transplant Congress

    mTORC1 and 2 Regulate Dendritic Cell (DC) Metabolism and Allostimulatory Function of Donor DCs in Skin Transplantation.

    A. Watson,1,2 H. Dai,1,3 A. Menk,4,5 G. Delgoffe,4,5 A. Thomson.1,2,3

    1Starzl Transplantation Institute, Univ. of Pittsburgh, Pittsburgh; 2Pathology, Univ. of Pittsburgh, Pittsburgh; 3Surgery, Univ. of Pittsburgh, Pittsburgh; 4Immunology, Univ. of Pittsburgh, Pittsburgh; 5Cancer Institute, Univ. of Pittsburgh, Pittsburgh

    Background/Hypothesis: The mechanistic target of rapamycin (mTOR) is a kinase that functions in two complexes: rapamycin (RAPA)-sensitive mTORC1 and RAPA-insensitive mTORC2. These complexes play critical…

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  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
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  • Penis Transplantation: First U.S. Experience.
  • Live Related Kidney Transplant Experience in Abuja, Nigeria – First Eight Cases Ever.
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  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
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