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Articles tagged "Mice, knockout"

  • 2019 American Transplant Congress

    Lymphotoxin Beta Receptor in Lymphatic Endothelial Cells Regulates Treg Migration and Allograft Protection

    V. Saxena, W. Piao, L. Li, C. M. Paluskievicz, Y. Xiong, T. Simon, J. S. Bromberg

    U Maryland, Baltimore, MD

    *Purpose: Lymphotoxin beta receptor (LTβR) mediated signaling in lymphatic endothelium cells (LEC) is important for migration of regulatory T cells (Treg) to afferent lymphatic vessels…
  • 2019 American Transplant Congress

    Laminin α5 Deficiency in Lymph Node Stromal Cells Promotes Treg Migration and Allograft Survival

    L. Li, M. Shirkey, W. Piao, Y. Xiong, V. Saxena, T. Zhang, T. Simon, N. Toney, C. Paluskievicz, J. S. Bromberg

    Surgery, U. Maryland, Baltimore, Baltimore, MD

    *Purpose: Laminins are a family of heterotrimeric glycoproteins, and lymph node (LN) stromal laminins α4 and α5 modulate suppression and immunity, respectively. We created laminin…
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