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American Transplant Congress abstracts

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Articles tagged "Metabolic complications"

  • 2015 American Transplant Congress

    Diabetes Exacerbates Liver Ischemia and Reperfusion Injury By Activating the AGE-RAGE Pathway in Kupffer Cells

    S. Yue, J. Zhu, J. Rao, J. Kupiec-Weglinski, R. Busuttil, Y. Zhai.

    Surgery, UCLA, Los Angeles, CA.

    Although pre-transplant diabetes has been documented as a risk factor for mortality post-liver transplant, the underlying mechanism remains obscure. In a murine liver partial warm…
  • 2015 American Transplant Congress

    A Prospective and Randomized Study of Conversion from Tacrolimus to Cyclosporine A to Improve Glucose Metabolism in Patients With New-Onset Diabetes Mellitus After Renal Transplantation

    K. Wissing,1 D. Abramowicz,2 L. Weekers,3 K. Budde,4 T. Rath,5 O. Witzke,6 D. Kuypers.7

    1Universitair Ziekenhuis Brussel, Brussels, Belgium; 2Universitair Ziekenhuis Antwerpen, Antwerpen, Belgium; 3Centre Hospitalier Universitaire Liège, Liège, Belgium; 4Charité Universitätsmedizin Berlin, Berlin, Germany; 5Westpfalz Klinikum Kaiserslautern, Kaiserslautern, Germany; 6Universitätsklinikum Essen, Essen, Germany; 7Universitair Ziekenhuis Leuven, Leuven, Belgium.

    Background: The present prospective and randomized study was designed to assess whether conversion from tacrolimus (Tac) to cyclosporine A (CsA) can reverse posttransplantation diabetes mellitus…
  • 2015 American Transplant Congress

    Bariatric Surgery Prolongs Allograft Survival by Promoting Th2 Conditions

    M. Quante, A. ElKhal, H. Rodriguez, R. Abdi, F. Krenzien, H. Uehara, S. Tullius.

    Division of Transplant Surgery and Transplant Surgery Research Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston.

    Background: Obesity is linked to chronic low-grade inflammation. We hypothesized that I) obesity will accelerate allograft rejection linked to pro-inflammatory immune responses and that II)…
  • 2015 American Transplant Congress

    Longitudinal Assessment of Endothelial Function Following Kidney Transplantation

    C. Kensinger,1 G. Chen,2 A. Bian,2 T. Ikizler,3 K. Birdwell.3

    1Department of General Surgery, Vanderbilt University Medical Center, Nashville, TN; 2Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN; 3Department of Medicine, Division of Nephrology, Vanderbilt University Medical Center, Nashville, TN.

    Purpose:Evaluate the progression of endothelial function as a marker of cardiovascular disease following kidney transplant.Background:Endothelial dysfunction is associated with cardiovascular disease (CVD) in end stage…
  • 2015 American Transplant Congress

    Pre-Transplant Weight Change and New-Onset Diabetes After Kidney Transplantation

    E. Huang, B. Abdalla, M. Andre, S. Bunnapradist.

    Dept of Medicine, UCLA School of Medicine, Los Angeles, CA.

    Background:We studied the association between pre-transplant weight change and new-onset diabetes after kidney transplant (NODAT).Methods:Using OPTN/UNOS data with follow-up to October, 2012, all adult (age>18…
  • 2015 American Transplant Congress

    Analytic Morphomics May Identify Risk Factors for New Onset Diabetes After Kidney Transplantation

    D. Cron,1 M. Terjimanian,1 J. Augustine,2 D. Cote,3 K. Noon,3 V. Vaughn,4 S. Wang,1 M. Englesbe,1 K. Woodside.3

    1Surgery, University of Michigan Medical School, Ann Arbor, MI; 2Medicine, Case Western Reserve University, Cleveland, OH; 3Surgery, Case Western Reserve University, Cleveland, OH; 4Internal Medicine, University of Michigan Medical School, Ann Arbor, MI.

    Intro:We have previously shown that analytic morphomics can predict risk of new-onset diabetes after liver transplantation (NODAT). We hypothesize that these methods may be able…
  • 2015 American Transplant Congress

    Serial Changes in Body Composition After Kidney Transplantation

    S. Deger,1 A. Bian,2 G. Chen,2 T. Ikizler,1 K. Birdwell.1

    1Medicine, Vanderbilt University Medical Center, Nashville, TN; 2Biostatistics, Vanderbilt University Medical Center, Nashville, TN.

    BACKGROUND: A significant long-term nutritional problem after kidney transplantation is obesity. We examined the changes in body composition after transplantation and its determinants.METHODS: A total…
  • 2015 American Transplant Congress

    Hyperuricemia Takes a Toll in Graft Function, Left Ventricular Diameters and Arterial Stiffness in Renal Transplant Recipients

    B. Gurlek Demirci,1 S. Sezer,1 C. Oygur,2 Z. Bal,1 E. Tutal,1 M. Haberal.3

    1Department of Nephrology, Baskent University Faculty of Medicine, Ankara, Turkey; 2Department of Internal Medicine, Baskent University Faculty of Medicine, Ankara, Turkey; 3Department of General Surgery, Baskent University Faculty of Medicine, Ankara, Turkey.

    Purpose: Cardiovascular diseases are the leading cause of morbidity and mortality in renal transplant recipients (RTRs). Serum uric acid (UA) levels correlate with many recognized…
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