ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "marginal"

  • 2018 American Transplant Congress

    Outcomes from Brain Death Donors with Cardiac Arrest Accepted for Pancreas Transplantation

    P. Ventura-Aguiar,1 J. Ferrer,2 D. Paredes,3 C. Rodriguez,3 C. Fontdevilla,2 E. Esmatjes,4 J. Garcia-Valdecasas,2 F. Oppenheimer,1 F. Diekmann,1 M. Ricart.1

    1Nephrology and Kidney Transplant Department, Hospital Clinic, Barcelona, Spain; 2Hepatobiliopancreatic and Liver Transplant Department, Hospital Clinic, Barcelona, Spain; 3Organ Transplantation Coordination Department, Hospital Clinic, Barcelona, Spain; 4Diabetes Unit, Department of Endocrinology and Nutrition, Hospital Clinic, Barcelona, Spain.

    Donor selection has a major impact on pancreas transplantation. Cardiac arrest and hypoxemia produce an insult to endothelial cell and may increase the risk of…
  • 2018 American Transplant Congress

    Hard-To-Place Kidney Offers: Granular Examination of Donor Risk Factors for Discard

    R. Narvaez, J. Nie, K. Noyes, M. Leeman, L. Kayler.

    Dept of Surgery, University at Buffalo, Buffalo, NY; Dept of Epidemiology and Environmental Sciences, University at Buffalo, Buffalo, NY; Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY.

    Background: Deceased-donor kidney discard rates remain high. Understanding risk factors for discard is difficult since most analyses lack granularity and sufficient sample of high disease…
  • 2018 American Transplant Congress

    Excellent Long Term Outcomes Transplanting Single Pediatric Kidneys from Donors Five Years and Younger into Adult Recipients

    R. Shah,1 M. Aull,2 A. Watkins,2 S. Kapur.2

    1Department of Surgery, Lincoln Medical Center, New York, NY; 2Surgery/Transplant Surgery, NewYork-Presbyterian/Weill Cornell Medical College, New York, NY.

    Pediatric kidneys have been traditionally considered marginal organs for transplantation & are underutilized given concerns of poor outcomes. Furthermore, long term outcomes of single kidneys…
  • 2017 American Transplant Congress

    Nucleic Acid Scavenging Microfiber Mesh Inhibits Trauma Induced Inflammation and Thrombosis After Organ Transplantation.

    J. Kwun,1 J. Lee,1 J. Jackman,2 M. Manook,1 E. Elster,3 A. Kirk,1 B. Sullenger.1

    1Surgery, Duke University, Durham, NC; 2Biomedical Engineering, Duke University, Durham, NC; 3Surgery, Uniformed Services University of Health Sciences and Walter Reed National Military Medical Center, Bethesda, MD

    [Introduction] Trauma patients produce a host of danger signals and high levels of damage-associated molecular patterns (DAMPs) after cellular injury and tissue damage. Organs from…
  • 2017 American Transplant Congress

    Variations in Risk-Appetite Between UK Kidney Transplant Centres and Impact on Patient and Graft Outcomes.

    P. Trotter,1,2 M. Robb,2 D. Summers,1,2 J. Bradley,1 J. Neuberger,2,4 C. Callaghan.2,3

    1Department of Surgery, University of Cambridge, Cambridge, United Kingdom; 2Organ Donation and Transplantation, NHS Blood and Transplant, Bristol, United Kingdom; 3Transplant Unit, Guys and St Thomas' NHS Foundation Trust, London, United Kingdom; 4Liver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom

    Introduction: Risks associated with deceased donors may be donor-related, organ-related, or both. Variations between transplant centres in the risks they are prepared to accept ('risk…
  • 2017 American Transplant Congress

    Model to Predict Prolonged Delayed Graft Function (DGF) Following Kidney Transplantation from Deceased Donor with Acute Kidney Injury (AKI Tx).

    R. Heilman,1 B. Smith,2 C. Johnson,1 H. Khamash,1 K. Reddy,1 W. Kremers,2 B. Kaplan.1

    1Mayo Clinic, Phoenix, AZ; 2Mayo Clinic, Rochester, MN

    Background Our aim is to develop a model to predict prolonged DGF following AKI Tx.Methods AKI Tx (donor terminal Cr>/=2) from 2003 to 2016 were…
  • 2017 American Transplant Congress

    MELD-Based Allocation Leads to Inferior Survival After Liver Transplantation.

    P. Ritschl, L. Wiering, M. Hippler-Benscheidt, F. Aigner, M. Biebl, M. Schmelzle, K. Kotsch, J. Pratschke, R. Öllinger.

    Department of Surgery, Campus Virchow and Mitte, Charité-Universitätsmedizin Berlin, Berlin, Germany

    Introduction and BackgroundThe MELD-based allocation system has been implemented in Germany in 2006 in order to decrease waiting list mortality in patients with end stage…
  • 2017 American Transplant Congress

    KDPI Obscures Trends in Absolute Donor Risk.

    N. Salkowski, S. Gustafson, A. Wey, J. Snyder.

    Scientific Registry of Transplant Recipients, Minneapolis, MN

    The kidney donor profile index (KDPI) is commonly used to measure deceased donor kidney quality based on the kidney donor risk index (KDRI) (Rao, et…
  • 2017 American Transplant Congress

    Induction Immunotherapy in ECD and DGF Kidneys: Does ECD Equal Diminishing Induction Returns?

    M. Barrett, A. Smith, K. Woodside, R. Sung.

    University of Michigan, Ann Arbor

    The benefit of induction immunotherapy to prevent DGF or mitigate its effects in recipients of marginal kidneys is not well understood and practices vary. We…
  • 2017 American Transplant Congress

    Post-Transplant Reduction in Pre-Existing Donor-Specific Antibody Levels After Belatacept- vs Cyclosporine-Based Immunosuppression.

    R. Bray,1 H. Gebel,1 R. Townsend,2 M. Polinsky,2 L. Yang,2 U. Meier-Kriesche,2 C. Larsen.1

    1Emory University, Atlanta, GA; 2Bristol-Myers Squibb, Lawrenceville, NJ

    Purpose: We explored the effect of belatacept (bela)- and cyclosporine (CsA)-based immunosuppression (IS) on pre-existing donor-specific antibody (DSA) levels by mean fluorescence intensity (MFI) in…
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