Articles tagged "marginal"

2016 American Transplant Congress
Utilization and Discard of HCV+ Donor Livers in the Advent of Direct-Acting Antiviral Therapy.
M. Bowring, L. Kucirka, A. Massie, X. Luo, M. Sulkowski, D. Segev, C. Durand.
JHU, Baltimore.
While 45% of liver candidates are hepatitis C (HCV)-antibody positive (+) and might benefit from a HCV+ donor liver, only a small proportion receive one.…
2016 American Transplant Congress
Original KDRI Predicts Kidney Graft Failure in a Brazilian Cohort.
J. Reusing Jr.,¹ C. Nihei,¹ A. Lino de Souza,² E. David-Neto,¹ C. Ventura.³
¹Kidney Transplant Unit, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, SP, Brazil; ²Psychobiology Department, Universidade Federal de São Paulo, São Paulo, SP, Brazil; ³Renal Transplant Unit, Hospital das Clinicas of the University of Sao Paulo Medical School, São Paulo, SP, Brazil.
Current US allocation system for kidney transplantation (KT) is based on KDRI (Kidney Donor Risk Index). In Brazil, it is still based on HLA-compatibility; donor…
2016 American Transplant Congress
Kidney Transplantation from Thin Basement Membrane Nephropathy Donor.
C. Choi,¹ A. Han,¹ S.-Y. Kim,¹ S. Cho,¹ M.-J. Cho,¹ C. Lee,¹ S. Ahn,¹ S.-K. Min,¹ J. Ha,¹ M. Park,² S. Kim,³ I. Jung,¹ S.-I. Min.¹
¹Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea; ²Laboratory Medicine, Korea Organ Donation Agency, Seoul, Republic of Korea; ³Surgery, Myongji Hospital, Goyang, Gyeonggi-do, Republic of Korea.
PurposeThin basement membrane nephropathy (TBMN) is the most common cause of persistent glomerular hematuria. Most individuals with TBMN shows benign course, but it is hard…
2016 American Transplant Congress
Abrogating Donor-Derived Myd88 Signaling Impairs the Recruitment of Recipient Neutrophils and CD8 T Cells into Lung Allografts in Mice.
Z. Zheng,¹ J.-J. Wang,¹ X. Yeap,¹ X. Kang,¹ Y. Xie,¹ X. Luo,² Z. Zhang.¹
¹Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL; ²Division of Nephrology and Hypertension, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL.
Objectives: Transplant ischemia reperfusion injury (IRI) mediated primary graft dysfunction (PGD) remains the predominant cause of short- and long-term graft loss in lung transplantation. This…
2015 American Transplant Congress
Resolution of Glomerular Fibrin Thrombi in Deceased Donor Kidneys
R. Batra,¹ M. Smith,³ L. Thomas,² H. Khamash,² A. Moss,² J. Huskey,² A. Singer,¹ A. Mathur,¹ N. Katariya,¹ K. Reddy,¹ R. Heilman.²
¹Transplant Surgery, Mayo Clinic, Phoenix, AZ; ²Transplant Nephrology, Mayo Clinic, Phoenix, AZ; ³Pathology, Mayo Clinic, Phoenix, AZ.
BackgroundDeceased donor kidneys with Glomerular Fibrin Thrombi (GFT) are frequently discarded, but these kidneys may offer an opportunity to increase deceased donor organs. Our aim…
2015 American Transplant Congress
Outcome of Kidney Transplantation from Older Living Donors: Histological Evaluation Using Zero-Time Biopsy Specimens
K. Omoto,¹ D. Toki,¹ M. Okumi,¹ T. Shimizu,¹ H. Ishida,¹ K. Honda,² J. Koike,³ K. Tanabe.¹
¹Department of Urology, Tokyo Women's Medical University, Tokyo, Japan; ²Department of Pathology, Tokyo Women's Medical University, Tokyo, Japan; ³Department of Pathology, St. Marianna University, School of Medicine, Kawasaki, Japan.
OBJECTIVE: The relationship between preimplantation biopsy and graft outcome in kidney transplantations from older living donors has not been studied yet. We reviewed graft outcomes…
2015 American Transplant Congress
Survival Outcomes of Kidney Transplant Recipients from Expanded Criteria Donors: A Systematic Review and Meta-Analysis
A.-H. Querard,^1,2,3 F. Gillaizeau,^1,3 Y. Foucher,^1,3 E. Dantan,³ D. Larmet,¹ M. Lorent,³ L.-M. Pouteau,¹ C. Combescure,⁴ M. Giral.^1,3,5
¹Institute for Transplantation, Urology and Nephrology, CHU Nantes, Inserm U1064, Nantes University, Nantes, France; ²Centre Hospitalier Départemental de Vendée, La Roche sur Yon, France; ³EA 4275 SPHERE-bioStatistics, Pharmacoepidemiology and Human sciEnces REsearch, Nantes University, Nantes, France; ⁴CRC & Division of Clinical Epidemiology, Department of Health and Community Medicine, University of Geneva, Geneva, Switzerland; ⁵LabExTransplantex Nantes, Centre d'Investigation Clinique Biothérapie, Nantes, France.
Background: In 2002, UNOS proposed the use of Expanded Criteria Donors (ECD=brain dead donor > 60 years, or 50-59 years with two criteria: CVA as…
2015 American Transplant Congress
"In-House" Controlled Oxygenated Rewarming After Initial Static Cold Storage: First Clinical Application in Marginal Donor Livers
D. Hoyer,¹ Z. Mathé,¹ A. Gallinat,¹ A. Canbay,² J. Treckmann,¹ U. Rauen,³ A. Paul,¹ T. Minor.⁴
¹General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany; ²Gastroenterology and Hepatology, University Hospital Essen, Essen, Germany; ³Institute of Physiological Chemistry, University Hospital Essen, Essen, Germany; ⁴Surgical Research Division, University Hospital Bonn, Bonn, Germany.
IntroductionControlled oxygenated rewarming of cold stored livers by machine perfusion demonstrated a strong protective effect in preclinical studies. Here we report on the first clinical…
2015 American Transplant Congress
Outcome of Kidney Transplantation Using Right Versus Three Left Renal Arteries After Retroperitoneoscopic Donor Nephrectomy: A Single-Center Experience of 764 Cases
K. Omoto, M. Okumi, T. Shimizu, D. Toki, H. Ishida, K. Tanabe.
Department of Urology, Tokyo Women's Medical University, Tokyo, Japan.
OBJECTIVE:In laparoscopic donor nephrectomy (LDN), technical problems are less common in the right side than in the left side. In addition, several study series have…
2015 American Transplant Congress
The Donor Risk Index Does Not Accurately Classify Patients With or Without Graft Failure
E. Franco,¹ T. Athanasios,² N. Kemmer,³ L. Leone,¹ A. Alsina,¹ B. Djulbegovic.²
¹Surgery, TGMG/USF Morsani College of Medicine, Tampa, FL; ²Internal Medicine, Morsani College of Medicine, USF, Morsani College of Medicine, Tampa, FL; ³Hepatology, TGMG/USF Morsani College of Medicine, Tampa, FL.
In liver transplantation assessing risk of donor is paramount to graft survival. The donor risk index (DRI) was introduced as a predictor of graft failure…