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Articles tagged "Lung infection"

  • 2022 American Transplant Congress

    Risk Factors Associated with ICU Admission and Death in Patients Hospitalized with COVID-19 Differ Between Solid Organ Transplant and Non-Solid Organ Transplant Patients

    J. Schaenman, H. Byford, T. R. Grogan, Y. Motwani, O. Beaird, M. Kamath, E. Lum, K. Meneses, D. Sayah, D. Vucicevic, S. Saab

    David Geffen School of Medicine at UCLA, Los Angeles, CA

    *Purpose: Despite the large numbers of reports on patient risk factors for poor clinical outcomes with COVID-19, little is known about how these risks may…
  • 2022 American Transplant Congress

    Clinical Features and Outcomes of Hospitalized Solid Organ Transplant and Hematopoietic Stem Cell Recipients with Sars-CoV-2 Infection in the Midwestern United States: A Multi-Center Retrospective Cohort Study

    S. Tanna1, D. Florescu2, A. Majeed3, J. Banzon3, S. Waller4, A. Eid4, N. Barros Baertl5, D. Friedman6, K. Mullane7, M. Ison8

    1Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, IL, 2University of Nebraska Medical Center, Omaha, NE, 3Cleveland Clinic, Cleveland, OH, 4University of Kansas Medical Center, Overland Park, KS, 5Infectious Diseases, Indiana University, Indianapolis, IN, 6Infectious Diseases, University of Chicago, Chicago, IL, 7University of Chicago, Chicago, IL, 8Northwestern University Comprehensive Transplant Center, Chicago, IL

    *Purpose: Immunocompromised hosts are at risk for severe complications or death from SARS-CoV-2 infection. Few studies describe the clinical features, outcomes and treatment strategies in…
  • 2022 American Transplant Congress

    Early Clinical Experience With Alvr109, A Partially Hla-matched Sars-cov-2 Specific T-cell Therapy, In Immunocompromised Patients With Covid-19

    G. Haidar1, J. Jacobs2, K. Hughes2, K. McCormick2, A. Naqvi2, M. Agha2, T. Bogdanovich2, B. Johnson2, J. Kozar2, E. Lendermon2, C. Marino2, A. Raptis2, F. Silveira2, W. Marshall3, M. Miller3, E. Atillasoy3, J. Mellors2

    1University of Pittsburgh, Pittsburgh, PA, 2UPitt, Pittsburgh, PA, 3Allovir, Waltham, MA

    *Purpose: Therapies for COVID-19 in immunocompromised (IC) patients (pts), including transplant (tx) pts, are limited. We describe our experience with ALVR109, an allogeneic, partially HLA-matched…
  • 2022 American Transplant Congress

    Inhalation Alone versus Inhalation Plus Intravenous Colistin for Multidrug-Resistant Gram-Negative Bacterial Infection After Lung Transplantation

    H. Kim1, Y. Yang1, A. Woo2, S. Jeong3, S. Kim2, J. Lee1, M. Park2, H. Paik1

    1Department of thoracic and cardiovascular surgery, Yonsei University College of medicine, Seoul, Korea, Republic of, 2Division of Pulmonology, Department of Internal Medicine, Yonsei University College of medicine, Seoul, Korea, Republic of, 3Division of Infectious Disease, Department of Internal Medicine, Yonsei University College of medicine, Seoul, Korea, Republic of

    *Purpose: After lung transplantation, patients are exposed to the risk of various infections accounting for morbidity and mortality. Multidrug-resistant gram-negative (MDR-GN) bacteria are emerging pathogen.…
  • 2022 American Transplant Congress

    Surveillance with Allosure for Allograft Rejection and Infection in Lung Transplant

    M. M. Botros1, N. Sulejmani2, B. F. Reader3, B. C. Keller1

    1Pulmonary, Critical Care & Sleep Medicine, The Ohio State University, Columbus, OH, 2Medical Affairs, CareDx, South San Francisco, CA, 3Division of Transplant Surgery, The Ohio State University, Columbus, OH

    *Purpose: Measurement of plasma donor-derived cell-free DNA (dd-cfDNA; AlloSure, CareDx) has been shown to be a useful non-invasive diagnostic test for injury and infection after…
  • 2022 American Transplant Congress

    Utility of Cytomegalovirus T-Cell Immunity Panel to Predict CMV Infections in Lung Transplant Recipients

    R. W. Lincoln1, B. J. Pierce1, C. Pham1, S. W. Yau2, A. Goodarzi2, J. G. Youssef2, H. J. Huang2

    1Pharmacy, Houston Methodist Hospital, Houston, TX, 2Pulmonology, Houston Methodist Hospital, Houston, TX

    *Purpose: Given the limited data of cytomegalovirus T-cell immunity panels (CMV TCIP) in lung transplant recipients (LTR), we sought to describe our center’s experience with…
  • 2022 American Transplant Congress

    Oseltamivir for the Prevention of Influenza Infection in Lung Transplant Recipients at an Academic Medical Center

    D. Majmundar, A. Mishkin, J. Burnell, C. Ruggia-Check, J. Au

    Temple University Hospital, Philadelphia, PA

    *Purpose: Influenza is commonly considered a community acquired infection, but in transplant recipients, nosocomial transmission is frequently encountered. The lung transplant program at Temple University…
  • 2022 American Transplant Congress

    Evaluation of Voriconazole Dosing for Preventing Aspergillus in Lung Transplant Recipients

    A. Chaplain1, B. J. Pierce1, C. Pham1, A. Hutchins1, W. L. Musick1, D. T. Nguyen2, E. A. Graviss2, S. W. Yau3, J. G. Youssef3, A. Goodarzi3, H. J. Huang3

    1Pharmacy, Houston Methodist Hospital, Houston, TX, 2Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX, 3Medicine, Houston Methodist Hospital, Houston, TX

    *Purpose: We sought to evaluate the efficacy of voriconazole (VCZ) 200 mg twice a day (BID) for 3 months post lung transplant (LT) in preventing…
  • 2022 American Transplant Congress

    Impact of Mycetoma in Lung Transplant Recipients

    A. Majeed, S. Singh, J. Lum

    CCF, Cleveland, OH

    *Purpose: Mycetoma are uncommon in lung transplant recipients (LTRs) and previous studies describe poor outcomes. We reviewed our experience*Methods: Retrospective review of electronic medical records…
  • 2022 American Transplant Congress

    Impact of Respiratory Viral Panel Testing on Clinical Decision-Making Among Lung Transplant Recipients Based on Extent of Immunosuppression

    A. C. Vostal1, A. Lynen2, S. Chintalapati1, M. Uehling1, K. Prakash2, A. Shishido1, J. Baghdadi2

    1University of Maryland Medical Center, Baltimore, MD, 2University of Maryland School of Medicine, Baltimore, MD

    *Purpose: Lung transplant recipients (LTRs) are at high risk for complications from viral respiratory infection, including chronic allograft dysfunction. Thus, multiplex molecular testing for respiratory…
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