Articles tagged "Living donor"

2021 American Transplant Congress
In Search of a Better Outcome: Opting Into the Live Donor Paired Kidney Exchange Program
A. J. Vinson¹, B. Kiberd², K. J. Tennankore¹
¹Nova Scotia Health Authority Division of Nephrology, Departm, Halifax, NS, Canada, ²Medicine, Dalhousie University, Halifax, NS, Canada
*Purpose: Live donor kidney transplantation is the best option for patients with End-Stage Kidney Disease (ESKD), if a donor is available. However, this may not…
2021 American Transplant Congress
Kidney Paired Exchange in Children in the United-states
J. Hogan¹, A. G. Thomas², J. Verbesey³, D. L. Segev⁴
¹Transplant Research Center, Department of Surgery, Emory University, Atlanta, GA, ²Department of Epidemiology, University of North Carolina, Chapel Hill, NC, ³Department of Surgery, Medstar Georgetown Transplant Institute, Washington, DC, ⁴Department of Surgery, Johns Hopkins University, Baltimore, MD
*Purpose: Kidney paired exchange (KPE) plays an increasing role in the landscape of adult living donor transplant (LDTx) in the US. LDTx is the treatment…
2021 American Transplant Congress
Platelets Stimulate Liver Regeneration After Partial Liver Transplantation
K. Takahashi, C. Liang, K. Furuya, T. Oda
GI and HBP Surgery, University of Tsukuba, Tsukuba, Japan
*Purpose: Living donor liver transplant (LDLT) can sometimes be associated with impaired regeneration and severe ischemia/reperfusion (I/R) injury in the liver graft, resulting in small-for-size…
2021 American Transplant Congress
Alterations in Mineral Metabolism of Living Kidney Donors: Prospective Observational Study
H. Lee¹, E. Ko¹, H. Cho², C. Yang¹, B. Chung¹
¹Division of Nephrology, Department of Internal Medicine, Seoul St. Mary’s Hospital, Seoul, Korea, Republic of, ²Department of Urology, Seoul St. Mary’s Hospital, Seoul, Korea, Republic of
*Purpose: The aim of this study is to investigate whether reduction in glomerular filtration rate (GFR) after kidney donation causes mineral metabolism alterations, and also…
2021 American Transplant Congress
Perioperative Terlipressin Therapy Reduces the Risk of Acute Kidney Injury Post-Living Donor Liver Transplantation – A Systematic Review and Meta-analysis
A. V. Kulkarni, H. V. Tevethia, M. Sharma, P. Kumar, N. P. Rao, N. D. Reddy
Hepatology and Liver Transplantation, Asian Institute of Gastroenterology, Hyderabad, India
*Purpose: Acute kidney injury (AKI) after liver transplantation precludes calcineurin inhibitors' therapy and is associated with poor outcomes. Terlipressin (Tp) has mortality benefit in pre-transplant…
2021 American Transplant Congress
Right Kidneys and Kidneys with Complex Anatomy are More Likely to be Transplanted to the Waiting List in a National Kidney Paired Donation Program
N. Osbun¹, A. Thomas², A. Waterman³, J. Veale¹, D. Segev², D. Leeser⁴
¹Urology, University of California Los Angeles, Los Angeles, CA, ²Johns Hopkins University, Baltimore, MD, ³University of California Los Angeles, Los Angeles, CA, ⁴East Carolina University, Greenville, NC
*Purpose: In the era of laparoscopic donor nephrectomy, there is a preference for left kidneys with a single renal artery. In paired exchange, the receiving…
2021 American Transplant Congress
Long-Term Follow-Up of a Phase 2 Clinical Trial to Induce Tolerance in Living Donor Renal Transplant Recipients
J. Leventhal¹, J. Galvin², J. Mathew¹, L. Gallon¹, D. Belshe¹, M. Gibson¹, K. Ravindra³, M. Horwitz³, S. Ildstad⁴
¹Northwestern University, Comprehensive Transplant Center, Chicago, IL, ²Northwestern University, Chicago, IL, ³Duke Medical Center, Durham, NC, ⁴University of Louisville, Llouisville, KY
*Purpose: 37 subjects were transplanted in a phase 2 protocol based upon tolerogenic CD8+/TCR-facilitating cells (FCR001) to induce tolerance in recipients of living donor renal…
2021 American Transplant Congress
Kidney Transplant Associated Allergy Transfer After Living Donation
K. López-Vega, S. Davis
Division of Renal Diseases and Hypertension, Anschutz Medical Campus, University of Colorado, Aurora, CO
*Purpose: Donor to recipient IgE-mediated food allergy transfer has been described in non-kidney solid organ transplant. Here, we report a novel case of an adult…
2021 American Transplant Congress
Machine Learning Informs Utility-Based Non-Directed Living Liver Donor Allocation
K. Bambha¹, J. Perkins¹, M. Sturdevant¹, S. W. Biggins¹, R. Bakthavatsalam¹, P. Healey², A. Dick², J. Reyes¹
¹University of Washington, Seattle, WA, ²Seattle Children's, Seattle, WA
*Purpose: To maximize non-directed living liver donor graft utility, we developed analytic models predicting 10-year graft survival post liver transplant (LT).*Methods: We analyzed OPTN living…
2021 American Transplant Congress
The Benefits of Sharing Non-Directed Donors Nationally Through Paired Exchange
J. Verbesey¹, A. G. Thomas², A. D. Waterman³, J. Vucci¹, G. Vranic¹, A. Gilbert¹, S. Ghasemian¹, M. Cooper¹
¹Georgetown University Hospital, Washington, DC, ²Johns Hopkins University School of Medicine, Baltimore, MD, ³UCLA, Los Angeles, CA
*Purpose: Non-directed donors (NDDs) are a valuable resource that can “unlock” incompatible transplants. Recent advances in paired kidney exchange (PKE) suggest that NDDs may facilitate…