2020 American Transplant Congress
Persistent Fibrinolysis Shutdown in Liver Transplant Recipients is Associated with Early Allograph Dysfunction
*Purpose: Early allograph dysfunction (EAD) in liver transplantation has been attributed to microvascular thrombosis. Treating grafts at risk of EAD with tissue plasminogen activator (tPA)…2020 American Transplant Congress
Development of a Split Liver Machine Perfusion Protocol to Provide Comparative Controls in Assessing Therapeutic Interventions
*Purpose: Ex situ donor liver machine perfusion is developing into a promising tool to test organ viability prior to transplantation and vehicle to assess novel…2020 American Transplant Congress
Acute Rejection in Liver Transplant Recipients is a Rising Predictor of Death and Graft Failure in the Recent Era of Declining Hepatitis C Virus
*Purpose: Prior to 2013, hepatitis C virus (HCV) played a major role in liver transplant (LT) outcomes, and acute rejection (AR) was found to be…2020 American Transplant Congress
Small RNA Extracellular Vesicles Isolated from Liver Perfusate Provides Assessment of Organ Quality and Post Transplantation Graft Function
*Purpose: Donor quality plays a critical role during IRI and early graft outcomes. Extracellular vesicles (EVs) provide a novel source of valuable biomarkers that may…2020 American Transplant Congress
Activation of YAP Attenuates Hepatic Damage and Fibrosis in Liver Ischemia-Reperfusion Injury: From Bench to Bedside
1Dumont-UCLA Transplant Center, Los Angeles, CA, 2Shanghai Jiaotong University, Shanghai, China
*Purpose: Hepatic ischemia-reperfusion injury (IRI) is a major complication of hemorrhagic shock, liver resection and transplantation. YAP, the effector of Hippo pathway, is essential in…2020 American Transplant Congress
Liver Transplant Recipients with High DSA at Time of Transplant Do Not Have Increased Rejection or Mortality
*Purpose: Currently, there is controversy regarding transplanting livers in setting of high HLA-class ll DSA especially since prior studies demonstrated enhanced acute rejections in this…2020 American Transplant Congress
Platelets Stimulate Liver Regeneration in a 30% Partial Liver Transplantation Model in Rat
University of Tsukuba, Tsukuba, Japan
*Purpose: Liver transplantation (LT) is one of the most definitive treatments for patients with end-stage liver disease and acute liver failure, and it has been…2020 American Transplant Congress
New IGL-2 Perfusate in Liver HOPE Strategies
*Purpose: HOPE has shown to optimize graft liver preservation. However, the most used perfusion solutions as such as Belzer-MPS and its generics were initially for…2020 American Transplant Congress
Simultaneous Liver and Kidney Transplant Outcomes after “Safety Net” Policy Change
1University of Minnesota, Minneapolis, MN, 2Surgery, University of Minnesota, Minneapolis, MN
*Purpose: Criteria for listing for Simultaneous Liver and Kidney (SLK) transplant changed on August 10, 2017. These changes were implemented to standardize the criteria for…2020 American Transplant Congress
Uncontrolled DCD vs DBD Liver Transplantation in the United States: Is it Safe to Push the Envelope?
*Purpose: Uncontrolled donation after cardiac death (uDCD) liver transplantation has been theorized as a potential option to increase the donor pool due to the typical…
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