Articles tagged "Liver grafts"

2021 American Transplant Congress
Incorporation of Donor Liver Macrovesicular Steatosis Into Srtr Risk Adjustment Models for Deceased Donor Yield and Post-Transplant Outcome
A. Kwong¹, C. Wang², A. Wey³, N. Salkowski³, J. Snyder⁴, J. Wetmore², A. Israni², J. Lake⁴, P. Stock⁵, W. Kim¹
¹Stanford University, Redwood City, CA, ²Medicine, Hennepin Healthcare, Minneapolis, MN, ³Scientific Registry of Transplant Recipients, Minneapolis, MN, ⁴University of Minnesota, Minneapolis, MN, ⁵University of California, San Francisco, San Francisco, CA
*Purpose: The SRTR had not traditionally included biopsy results in post-transplant risk adjustment, yet biopsy results may influence outcomes and thus decisions regarding organ acceptance.…
2021 American Transplant Congress
Assessing Liver Transplant Outcomes Utilizing Post-Cross Clamp Offers
K. Pont¹, E. Macdonough¹, D. Das², K. Valenti¹, P. Morgan¹, B. Aqel¹, A. Mathur¹, A. Moss¹, K. S. Reddy¹, C. Jadlowiec¹
¹Mayo Clinic, Phoenix, AZ, ²Mayo Clinic Alix School of Medicine, Scottsdale, AZ
*Purpose: With the ongoing organ shortage, there has been increased interest in utilizing post-cross clamp (XC) liver allografts as a means of expanding the donor…
2021 American Transplant Congress
Recipient Selector for Donation After Cardiac Death Allografts
G. Handing¹, S. Ganni², S. Barrett¹, N. Galvan², C. O’Mahony², J. Goss², R. Cotton², A. Rana²
¹School of Medicine, Baylor College of Medicine, Houston, TX, ²Michael E DeBakey Department of Surgery, Division of Abdominal Transplant, Houston, TX
*Purpose: Donation after cardiac death (DCD) allografts might represent one of the largest untapped sources of liver allografts. Our aim was to identify independent donor…
2021 American Transplant Congress
Liver Transplantation with Super Obese Donors (BMI≥50) Grafts: An Acceptable Pathway to Expand the Donor Pool. Analysis of the OPTN/UNOS Liver Transplant Registry
P. Vargas¹, C. Argo², H. Zachary², M. Stotts², N. Intagliata², P. Northup², J. Oberholzer¹, S. Pelletier¹, N. Goldaracena¹
¹Transplant Surgery, University of Virginia Health System, Charlottesville, VA, ²Gastroenterology and Hepatology, University of Virginia Health System, Charlottesville, VA
*Purpose: We aimed to analyze the impact of donor body mass index (BMI) on recipient morbidity and survival following liver transplantation (LT).*Methods: The UNOS-STAR database…
2021 American Transplant Congress
Effect of Early Biopsy-Proven Rejection on Liver Transplant Outcomes
D. D. Aufhauser, N. Marka, L. Stalter, G. Levenson, D. Al-Adra, D. P. Foley
Surgery, University of Wisconsin, Madison, WI
*Purpose: Existing literature offers conflicting conclusions about whether early acute cellular rejection influences long-term outcomes in liver transplantation.*Methods: We retrospectively collected donor and recipient data…
2021 American Transplant Congress
Living Donor versus Deceased Donor Pediatric Liver Transplantation: A Systematic Review and Meta-Analysis of Outcomes
A. Barbetta¹, C. Butler², S. Barhouma², R. Hogen¹, B. Roque¹, H. Schillperoort³, G. Meeberg⁴, J. Shapiro⁵, Y. Kwon¹, R. Kohli⁶, J. Emamaullee¹
¹Surgery, abdominal transplat, University of Southern California, Los Angeles, CA, ²University of Southern California, Los Angeles, CA, ³Norris Medical Library, University of Southern California, Los Angeles, CA, ⁴Department of Surgery, University of Alberta, Edmonton, AB, Canada, ⁵Department of Surgery,, University of Alberta, Edmonton, AB, Canada, ⁶Department of Pediatrics, University of Southern California, Los Angeles, CA
*Purpose: Reduced size deceased donors and living donor liver transplantation (LDLT) can help address the organ shortage for pediatric liver transplant candidates. Concerns regarding technical…
2021 American Transplant Congress
Platelets Stimulate Liver Regeneration After Partial Liver Transplantation
K. Takahashi, C. Liang, K. Furuya, T. Oda
GI and HBP Surgery, University of Tsukuba, Tsukuba, Japan
*Purpose: Living donor liver transplant (LDLT) can sometimes be associated with impaired regeneration and severe ischemia/reperfusion (I/R) injury in the liver graft, resulting in small-for-size…
2021 American Transplant Congress
Portal Vein Challenges in Pediatric Liver Transplantation: The Utility of Interposition Grafts as an Acceptable Management Strategy
R. Hogen, K. Etesami, J. Cervantes, Y. Kwon, S. Zielsdorf, J. Emamaullee, Y. Genyk
Division of Hepatobiliary and Abdominal Organ Transplantation, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA
*Purpose: To examine our single center experience in the operative management of pediatric liver transplantation (LT) patients with challenging portal vein (PV) anomalies.*Methods: We retrospectively…
2021 American Transplant Congress
The Harmful Effect of Retained Peripheral Cells During Flushing and Static Cold Storage in Rat Liver Normothermic Machine Perfusion
O. Haque¹, C. A. Pendexter², J. F. Markmann², K. Uygun², H. Yeh², S. N. Tessier²
¹Surgery, Beth Israel Deaconess Medical Center, Boston, MA, ²Massachusetts General Hospital, Boston, MA
*Purpose: Retained donor blood in a liver graft can cause damage to resident cells that is exacerbated by static cold storage (SCS), leading to platelet…
2021 American Transplant Congress
Application of Linear Discriminant Analysis (lda) to Differentiate Acute Rejection (ar) and Acute Dysfunction Non-Rejection (adnr) in Liver Transplant Recipients
M. Miller¹, R. Sinha¹, J. Weems¹, J. Holman², M. Altrich¹, S. Kleiboeker¹, J. Levitsky³
¹R&D, Viracor-Eurofins, Lee's Summit, MO, ²Transplant Genomics, Mansfield, MA, ³R&D, Northwestern University Feinberg School of Medicine, Chicago, IL
*Purpose: Blood-based biomarkers distinguishing acute-rejection (AR) from other causes of graft dysfunction (acute dysfunction non-rejection (ADNR)) would have significant clinical applicability in liver transplant (LT)…