2022 American Transplant Congress
Cold Stress-Induced Ferroptosis in Liver Sinusoidal Endothelial Cells Deteriorates Liver Transplant Outcomes
UCLA Medical Center, Los Angeles, CA
*Purpose: While hepatocytes are affected by ischemia-reperfusion injury (IRI) especially under normothermic stress, liver sinusoidal endothelial cells (LSECs) are particularly vulnerable to cold storage-induced IR-insult.…2022 American Transplant Congress
Comparative Analysis of Liver Organ Offers Pre- and Post- Acuity Circle Policy Change in the US
*Purpose: With the intended goal of reducing geographic inequities, the United Network for Organ Sharing (UNOS) and Organ Procurement and Transplantation Network (OPTN) transitioned to…2022 American Transplant Congress
Final Report of the Use of α-Lipoic Acid in Liver Transplantation to Prevent Ischemia Reperfusion Injury
1Hospital Italiano, Buenos Aires, Argentina, 2CEFYBO, Buenos Aires, Argentina
*Purpose: The ischemia and reperfusion injury contributs to grafts deterioration and adverse post-transplant outcomes. The aim of the present study was to evaluate the safety…2022 American Transplant Congress
Real-Time Application of Deep Learning in Diagnosis of Graft Fibrosis After Liver Transplantation Using Longitudinal Data
*Purpose: Graft fibrosis develops insidiously in liver transplant recipients and is associated with worse survival. Early detection of fibrosis is essential to avoid further progression…2022 American Transplant Congress
Development of a Portable Device to Quantify Hepatic Steatosis in Donated Livers Using an AI Algorithm
1Computer Science, Stanford, Stanford, CA, 2Surgery, Stanford, Stanford, CA
*Purpose: An accurate estimation of liver fat content is necessary to predict how a donor liver will function after transplantation. This can be challenging at…2022 American Transplant Congress
Gene Profiling to Distinguish Mechanisms of Liver Allograft Rejection and Acceptance in Cynomolgus Monkey
*Purpose: Liver is an immune regulatory organ. Spontaneous resolutions from rejection have been seen in our orthotopic cynomolgus monkey liver transplant models for tolerance induction…2022 American Transplant Congress
End-to-Side Splenic to Hepatic Artery Reconstruction in Liver Transplant: A Case Series
Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT
*Purpose: Optimal hepatic artery (HA) blood flow post-liver transplantation (LT) is necessary for long-term allograft success. HA thrombosis (HAT) contributes to significant morbidity and mortality…2022 American Transplant Congress
Utilizing Microsurgeon Expertise in the Salvage of Hepatic Artery Dissection
*Purpose: Living donor hepatic artery intimal dissection is a rare but devastating complication often resulting in inability to utilize the graft. We detail the salvage…2022 American Transplant Congress
Pretransplant microRNAs in Liver Perfusate Associate with Early Allograft Dysfunction
University of Maryland School of Medicine, Baltimore, MD
*Purpose: Early allograft dysfunction (EAD) in liver transplantation (LT) is associated with poor long-term graft and patient survival. Prior to LT, while organs are stored…2021 American Transplant Congress
Platelets Stimulate Liver Regeneration After Partial Liver Transplantation
GI and HBP Surgery, University of Tsukuba, Tsukuba, Japan
*Purpose: Living donor liver transplant (LDLT) can sometimes be associated with impaired regeneration and severe ischemia/reperfusion (I/R) injury in the liver graft, resulting in small-for-size…
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