ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Liver grafts"

  • 2022 American Transplant Congress

    Impact of Donor-to-Recipient Body Surface Area Ratio on Graft Survival and Mortality Following Deceased Donor Liver Transplants

    S. Radomski, L. Zeiser, A. Massie, S. Ottmann, D. Segev, E. King

    Surgery, Johns Hopkins University, Baltimore, MD

    *Purpose: The impact of size mismatch on graft survival in living donor liver transplant is well established but is not a common concern in deceased…
  • 2022 American Transplant Congress

    Normothermic Machine Perfusion (NMP) Improves Access to Transplantation for Late Liver Re-Transplant Candidates

    D. Sneiders1, H. Lembach1, A. Hann1, A. Nutu1, J. Hodson1, J. Isaac1, R. Taylor2, M. Armstrong1, T. Perera1, H. Hermien1

    1Queen Elizabeth Hospital, Birmingham, United Kingdom, 2NHS Blood and Transplant, bristol, United Kingdom

    *Purpose: Late liver re-transplantation (LLrT) is a complex surgical procedure. Candidates for LLrT spend longer on the waitlist than primary transplant candidates due to selectivity…
  • 2022 American Transplant Congress

    Can We Predict Progression of Potential Donation After Cardiac Death Donors (DCD) Using DonorNet?

    Y. Bababekov1, A. Yule1, H. Moore1, R. Choudhury2, C. Hertert3, T. Pshak4, T. Nydam5, B. Kaplan1, E. Pomfret1, J. Pomposelli5

    1Transplant Surgery, University of Colorado, Aurora, CO, 2University of Colorado Hospital, Denver, CO, 3Donor Alliance, Denver, CO, 4University of Colorado, Denver, CO, 5University of Colorado, Aurora, CO

    *Purpose: DCD utilization of livers is limited by unpredictability of progression, perceived worse outcome, and costs related to deployment of resources. We aimed to predict…
  • 2022 American Transplant Congress

    Is Remnant Liver Volume Ratio Less Than 30% Still Contraindication to Right Hepatectomy for Living Liver Donors?

    J. Kim, D. Choi

    Department of Surgery, Catholic University of Daegu College of Medicine, Daegu, Korea, Republic of

    *Purpose: Recently, some centers reported that extended resection with remnant/total volume ratio(RTVR) less than 30% for living donor right hepatectomy(LDRH) but there is no consensus…
  • 2022 American Transplant Congress

    PACAP-Mediated Autophagy Prevents Liver Ischemia Reperfusion Injury in OLT

    Z. Xue, B. Yang, R. Busuttil, J. Kupiec-Weglinski, H. Ji

    UCLA Medical Center, Los Angeles, CA

    *Purpose: Pituitary adenylate cyclase-activating polypeptide (PACAP) is from vasoactive intestinal peptide-glucagon-secretin family. Our group was the first to demonstrate that neuropeptide PACAP, which innervates the…
  • 2022 American Transplant Congress

    Experience with the First Two Living Donor Robotic Left Lobe Hepatectomies in the USA

    M. E. Tobon Lascano, M. Akoad, C. Simon, J. Kim, Y. Cheah

    Transplant, Lahey Clinic, Burlington, MA

    *Purpose: Robotic living donor has been performed in a few centers with good outcomes; the first report of a robotic right lobe donor hepatectomy was…
  • 2022 American Transplant Congress

    The Role Of Ferroptosis In Modulating Ischemia Reperfusion Injury(IRI) Gene Expression In Marginal Donor Livers(MDLS) Using The Novel Protect Normothermic Perfusion Pump

    M. D. Nazzal1, K. Kurashima2, J. Bettag2, A. Chen2, S. Bruno2, A. Nagarapu2, J. Van Nispen1, J. Krebs2, J. Teckman2, D. Carpenter3, D. Hermelin3, C. Varma1, A. Jain2

    1Surgery, Saint Louis University, Saint Louis, MO, 2Pediatrics, Saint Louis University, Saint Louis, MO, 3Pathology, Saint Louis University, Saint Louis, MO

    *Purpose: Severe IRI can impair liver allograft when using MDLs and accounts for high discard rates. We tested iron chelators to reduce ferroptosis and IRI.…
  • 2022 American Transplant Congress

    Normothermic Machine Perfusion in Liver Transplantation – Seven Year Experience at a Single North American Centre

    J. Hefler1, D. L. Izuierdo1, G. Meeberg2, M. Bral1, B. Anderson1, K. Dajani1, N. Kneteman1, D. L. Bigam1, A. Shapiro1

    1Department of Surgery, University of Alberta, Edmonton, AB, Canada, 2Alberta Health Services, Edmonton, AB, Canada

    *Purpose: Machine perfusion for preservation of liver grafts before transplantation has risen in prominence over the past decade. Normothermic machine perfusion (NMP), in particular, has…
  • 2022 American Transplant Congress

    Cold Stress-Induced Ferroptosis in Liver Sinusoidal Endothelial Cells Deteriorates Liver Transplant Outcomes

    H. Kojima, H. Hirao, K. Kadono, T. Ito, K. J. Dery, F. Kaldas, J. Kupiec-Weglinski

    UCLA Medical Center, Los Angeles, CA

    *Purpose: While hepatocytes are affected by ischemia-reperfusion injury (IRI) especially under normothermic stress, liver sinusoidal endothelial cells (LSECs) are particularly vulnerable to cold storage-induced IR-insult.…
  • 2021 American Transplant Congress

    Can an Organ Survive for More Than 100 Years Between Donor and Recipient

    R. Gruessner, J. Renz, A. C. Gruessner

    SUNY Downstate Medical Center, Brooklyn, NY

    *Purpose: It has been hypothesized that parenchymal grafts have a longer life expectancy than the cardio-cerebro-vascular system. We investigated the occurrence of deceased-donor liver (DDOLT),…
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