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Articles tagged "Liver grafts"

  • 2016 American Transplant Congress

    Review of Aborted Hepatectomy of Liver Transplantation in a Single Center Study.

    J. Lee, G. Choi, W. Cho, J.-W. Joh, S.-K. Lee, S.-J. Kim, C. Kwon, J. Park, J. Kim.

    General Surgery, Samsung Medical Center, Seoul, Korea.

    Liver transplantation (LT) has become a popular option for the treatment of endstage hepatic failure. More attention has been given to donor safety, but still…
  • 2015 American Transplant Congress

    Liver Fabrication Using Whole Organ Scaffold for Transplantable Graft in Large Animal

    K. Inomata,1 H. Yagi,1 K. Tazima,1 K. Sugiyama,1 M. Hieda,1 T. Hibi,1 Y. Abe,1 M. Kitago,1 M. Shinoda,1 O. Itano,1 T. Akaike,2 Y. Kitagawa.1

    1Surgery, Keio University, Tokyo, Japan; 2Department of Biomolecular Engineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Tokyo, Japan.

    Background and aims: Orthotopic liver transplantation is only effective treatment for end-stage liver disease, however it is limited by shortage of donor livers. Therefore, novel…
  • 2015 American Transplant Congress

    Risk of Post Liver Transplant (LT) Hepatocellular Carcinoma (HCC) Recurrence Is 2-Fold Higher in Women Compared to Men With AFP Levels at LT Between 101-500

    M. Sarkar,1 J. Dodge,2 F. Yao,1 J. Roberts,2 N. Terrault,1 N. Mehta.1

    1Medicine, University of California, San Francisco, San Francisco; 2Surgery, University of California, San Francisco, San Francisco.

    Gender differences in HCC incidence are known, with men at greater risk than women. Pre transplant AFP levels strongly predict post LT HCC recurrence, though…
  • 2015 American Transplant Congress

    Increased Fibroblast Growth Factor 21 Levels in Biliary Atresia Patients

    D. Li, T. Lu, Y. Shan, C. Shen, X. Hua, M. Zhang, Q. Xia.

    Renji Hospital, Shanghai, China.

    Background: Fibroblast growth factor (FGF)-21, a hormone predominantly secreted by the liver, has recently been reported as a key circulating adipokine involving in metabolic disorders…
  • 2015 American Transplant Congress

    Legal Issues in Domino Liver Transplantation in Germany

    H. Schmidt,1 A. Barreiros,2 H. Schlitt,2 T. Gutmann.3

    1Klinik für Transplantationsmedizin, Universitätsklinikum Münster, Münster, Germany; 2Universitätsklinikum Regensburg, Regensburg, Germany; 3Rechtswissenschaftliche Fakultät, Westfälische Wilhelms-Universität Münster, Münster, Germany.

    TTR-amyloidosis (FAP) is caused by TTR variants expressed and secreted by the liver. Therefore, liver transplantation was introduced as therapeutic option to prevent or limit…
  • 2015 American Transplant Congress

    Liver Allograft Provides Immunoprotection for the Cardiac Allograft in Combined Heart-Liver Transplantation

    T. Wong, J. Stulak, J. Heimbach, M. Stegall, T. Taner.

    Mayo Clinic, Rochester, MN.

    When transplanted simultaneously, the liver allograft has been thought to have an immunoprotective role on other organs. However, detailed studies on simultaneous heart-liver transplantation (SHLT)…
  • 2015 American Transplant Congress

    Early Allograft Dysfunction Causes Inferior Patient and Allograft Survival in Liver Transplantation; an Experience of 1952 Consecutive Liver Transplants

    D. Lee, K. Croome, J. Burns, D. Perry, J. Nguyen, H. Crespo, C. Taner.

    Transplantation, Mayo Clinic, Jacksonville, FL.

    Background: Early allograft dysfunction (EAD) in liver transplantation (LT) is a useful intermediate outcome measure to predict graft loss or mortality. We sought to investigate…
  • 2015 American Transplant Congress

    Liver Allograft Utilization Within the United States: 2003-2013

    J. Renz,1 G. Diaz,1 L. Ratner,2 H. Yersiz,3 M. Millis,1 J. Matthews.1

    1Department of Surgery, University of Chicago, Chicago, IL; 2Department of Anesthesia/Critical Care, University of Chicago, Chicago, IL; 3Department of Surgery, Columbia University, New York, NY; 4Department of Surgery, University of California Los Angeles, Los Angeles, CA.

    Objectives: 1) Evaluate liver allograft availability, utilization, and failure probability utilizing the liver donor risk index(LDRI) 2) Correlate allograft utilization with waitlist mortality and incidence…
  • 2015 American Transplant Congress

    Losartan Benefits Are Mediated Through SIRT1 Activation in Rat Reduced Size Orthotopic Liver Transplantation

    E. Pantazi,1 M. Bejaoui,1 M. Zaouali,1 E. Folch-Puy,1 A. Rolo,2,3 A. Panisello,1 C. Palmeira,2 J. Rosello-Catafau.1

    1Experimental Pathology, Institute of Biomedical Research of Barcelona (IIBB-CSIC), Barcelona, Spain; 2Department of Life Sciences, Faculty of Science and Technology, University of Coimbra, Coimbra, Portugal; 3Center for Neurosciences and Cell Biology, Department of Zoology, University of Coimbra, Coimbra, Portugal.

    Background: Silent Information Regulator 1 (SIRT1) is a histone deacetylase that has been associated with protective mechanisms against IRI, but its role in liver transplantation…
  • 2015 American Transplant Congress

    Anti-Apoptotic But Not Mitotic Effects of 3,3',5-triiodo-l-thyronine in the Liver of Brain Dead Rats

    A. van Erp,1 R. Rebolledo,2 J. Wiersema-Buist,1 P. Ottens,1 H. Leuvenink,1 P. Romanque.2

    1Department of Surgery, University Medical Center Groningen, Groningen, Netherlands; 2Department of Surgery, University of Chile, Santiago, Chile.

    Thyroid hormone treatment in brain dead organ donors has been extensively studied and applied in the clinical setting. However, its effectiveness remains controversial due to…
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