2016 American Transplant Congress
A Users Guide to Maximizing Utility and Outcome in >70 Year Old Donors.
Liver Transplant & HPB Surgery, Weill Cornell Medical College, NY, NY.
Background Among 10 million stroke fatalities in the US since 2002, donated livers were recovered from 28,313. Unfortunately, only 2,402 livers were yielded from 7.5…2016 American Transplant Congress
Outcomes of Ductoplasty in Right Lobe Living Donor Grafts with More Than One Bile Duct.
Background:Biliary complications remain the Achilles's heel of LDLT, especially in the setting of multiple ducts in the right lobe graft. Hilar plate glissonian sheath preservation…2016 American Transplant Congress
Subnormothermic Machine Perfusion (SNMP) Leads to Increased Bile Production and Secretion of Hydrophilic Bile Acids After Liver Transplantation When Compared to Cold Storage (CS).
University of Pittsburgh, Pittsburgh.
Background: Bile production during machine perfusion and after transplantation has been used as marker of liver allograft viability and function. This study aimed to assess…2016 American Transplant Congress
A Multi-Modular Approach for Training in Liver Procurement Accelerates Proficiency Gain.
BACKGROUND: Modular training has been established as an educational tool in colorectal and urology surgery for the last 5 years. This modular operative approach is…2016 American Transplant Congress
Good Livers with a Bad Reputation: Favorable Outcome with Imported Grafts.
Transplantation, Lahey Hospital and Medical Center, Burlington, MA.
Background: Each year in the US, 450-500 livers are discarded as unacceptable for transplant. Currently, there is controversy about the implications of broader sharing and…2016 American Transplant Congress
Resolution of Donor Non-Alcoholic Fatty Liver Disease Following Liver Transplantation.
Purpose: Severe and moderate degrees of donor liver steatosis have traditionally limited the transplantation of these organs. The natural history of successfully transplanted livers with…2016 American Transplant Congress
Liver Graft Steatosis Associates with an Increase of Circulating Immune Response Chemokines.
University of Virginia, Charlottesville.
Background: Liver graft steatosis, especially macrosteatosis induces severe graft injury post-liver transplantation (LT) by activating cell-mediated immunity and inflammation. This study aimed to determine differential…2016 American Transplant Congress
Liver Graft Rejuvenation Prior to Transplantation: A Bench-to-Bedside Approach.
1Surgery, Dumont-UCLA Translant Center, Los Angeles, CA; 2Pathology, UCLA, Los Angeles, CA.
To address the shortage of organs for transplantation many use “marginal” livers, which are particularly susceptible to ischemia-reperfusion injury (IRI). We have taken a two-pronged…2016 American Transplant Congress
Attenuation of Warm Hepatic Ischemia-Reperfusion Injury by Bruton's Tyrosine Kinase Inhibition.
1Surgery, Dumont-UCLA Translant Center, Los Angeles, CA; 2Pathology, UCLA, Los Angeles, CA.
Bruton's tyrosine kinase (Btk) is a central player in multiple signaling pathways in lymphoid and myeloid cells, including neutrophils. Neutrophils are crucial effectors in the…2016 American Transplant Congress
Stress Cardiomyopathy in the Perio-Perative Period After Liver Transplant.
Purpose: Stress cardiomyopathy is a pathological condition in which excess catecholamines leading to cardiac dysfunction. This phenomenon is associated with troponin elevation, EKG changes, and…