Articles tagged "Liver grafts"

2017 American Transplant Congress
Donor Body Mass Index and Utilization of Liver Biopsy: An Evaluation of National Practices and Organ Utilization.
J. Steggerda,¹ D. Marguiles,¹ D. Malinoski,² M. Bloom.¹
¹Surgery, Cedars-Sinai Medical Center, Los Angeles, CA; ²Surgery, Oregon Health and Science University, Portland, OR
Background: As the prevalence of obesity in America increases, so has the proportion of donors with elevated body mass index (BMI). While graft steatosis >30%…
2016 American Transplant Congress
A Multi-Modular Approach for Training in Liver Procurement Accelerates Proficiency Gain.
I. Al Hasan,^1,2 H. Sharma,^1,2 M. Tun-Abraham,¹ D. Quan.^1,2
¹Department of Surgery, Schulich School of Medicine & Dentistry, University of Western Ontario, London, ON, Canada; ²Multi-Organ Transplant Program, London Health Sciences Centre, London, ON, Canada.
BACKGROUND: Modular training has been established as an educational tool in colorectal and urology surgery for the last 5 years. This modular operative approach is…
2016 American Transplant Congress
Good Livers with a Bad Reputation: Favorable Outcome with Imported Grafts.
M. Akoad, M. Simpson, J. Pomposelli, E. Pomfret.
Transplantation, Lahey Hospital and Medical Center, Burlington, MA.
Background: Each year in the US, 450-500 livers are discarded as unacceptable for transplant. Currently, there is controversy about the implications of broader sharing and…
2016 American Transplant Congress
Resolution of Donor Non-Alcoholic Fatty Liver Disease Following Liver Transplantation.
A. Posner,¹ W. Twaddell,² S. Hanish,² D. Bruno,² W. Hutson,² L. Hebert,² R. Barth,² J. LaMattina.²
¹University of Maryland School of Medicine, Baltimore, MD; ²Division of Transplantation, University of Maryland School of Medicine, Baltimore, MD.
Purpose: Severe and moderate degrees of donor liver steatosis have traditionally limited the transplantation of these organs. The natural history of successfully transplanted livers with…
2016 American Transplant Congress
Liver Graft Steatosis Associates with an Increase of Circulating Immune Response Chemokines.
R. Gehrau, V. Mas, A. Sharma, V. Bontha, D. Maluf.
University of Virginia, Charlottesville.
Background: Liver graft steatosis, especially macrosteatosis induces severe graft injury post-liver transplantation (LT) by activating cell-mediated immunity and inflammation. This study aimed to determine differential…
2016 American Transplant Congress
Liver Graft Rejuvenation Prior to Transplantation: A Bench-to-Bedside Approach.
A. Zarrinpar,¹ B. Ke,¹ H. Ji,¹ E. Reed,² R. Busuttil,¹ J. Kupiec-Weglinski.¹
¹Surgery, Dumont-UCLA Translant Center, Los Angeles, CA; ²Pathology, UCLA, Los Angeles, CA.
To address the shortage of organs for transplantation many use “marginal” livers, which are particularly susceptible to ischemia-reperfusion injury (IRI). We have taken a two-pronged…
2016 American Transplant Congress
Attenuation of Warm Hepatic Ischemia-Reperfusion Injury by Bruton's Tyrosine Kinase Inhibition.
A. Zarrinpar,¹ T. Palumbo,¹ K. Nakamura,¹ C. Lassman,² R. Busuttil,¹ J. Kupiec-Weglinski.¹
¹Surgery, Dumont-UCLA Translant Center, Los Angeles, CA; ²Pathology, UCLA, Los Angeles, CA.
Bruton's tyrosine kinase (Btk) is a central player in multiple signaling pathways in lymphoid and myeloid cells, including neutrophils. Neutrophils are crucial effectors in the…
2016 American Transplant Congress
Stress Cardiomyopathy in the Perio-Perative Period After Liver Transplant.
N. Presser, B. Barzilai.
General Surgery, Clevelanc Clinic Foundation, Cleveland, OH; Cardiology, Cleveland Clinic Foundation, Cleveland, OH.
Purpose: Stress cardiomyopathy is a pathological condition in which excess catecholamines leading to cardiac dysfunction. This phenomenon is associated with troponin elevation, EKG changes, and…
2016 American Transplant Congress
Review of Aborted Hepatectomy of Liver Transplantation in a Single Center Study.
J. Lee, G. Choi, W. Cho, J.-W. Joh, S.-K. Lee, S.-J. Kim, C. Kwon, J. Park, J. Kim.
General Surgery, Samsung Medical Center, Seoul, Korea.
Liver transplantation (LT) has become a popular option for the treatment of endstage hepatic failure. More attention has been given to donor safety, but still…
2016 American Transplant Congress
Intra-Operative Hepatic Arterial Flow Predicts Hepatic Artery Complications After Deceased Donor Liver Transplantation.
H. Fernandez, G. Testa, G. Klintmalm, P. Kim.
Baylor University, Dallas, TX.
IntroductionHepatic arterial flow (HAF) is important for post liver transplant outcomes. This study was conducted to determine the predictive value of measured intraoperative HAF on…