ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Liver grafts"

  • 2018 American Transplant Congress

    Assessment of Hepatic Ischemia-Reperfusion Injuries by NRF2-Dependent Transcriptional Activities of Bile Transporters in Rats

    J. Kim,1 A. Martin,1 J. Yee,1 L. Fojut,1 A. Geurts,2 K. Oshima,3 M. Zimmerman,1 J. Hong.1

    1Surgery, Medical College of Wisconsin, Milwaukee, WI; 2Physiology, Medical College of Wisconsin, Milwaukee, WI; 3Pathology, Johns Hopkins University School of Medicine, Baltimore, MD.

    Background: The effect of hepatic ischemia and reperfusion injury (IRI) on bile transporter (BT) gene expression and the role of Nrf2 in BT regulation during…
  • 2018 American Transplant Congress

    Living Donor Liver Transplant (LDLT) at a Single Center- Intraoperative Technical Modifications and Optimization of Flow Dynamics to Improve Outcomes

    A. Humar, S. Ganesh, A. Tevar, M. Molinari, C. Hughes.

    Surgery, University of Pittsburgh, Pittsburgh.

    Objectives: While LDLT represents the dominant method of LTx in the East, it remains an underutilized procedure in the US, accounting for <5% of all…
  • 2018 American Transplant Congress

    Involvement of Aldehyde Dehydrogenase 2 (ALDH2) in Fatty Liver Graft Protection Mechanisms against Cold Ischemic Injury

    A. Panisello-Rosello,1 A. Lopez,2 C. Castro,2 S. Bellogi,1 E. Folch-Puy,1 A. Rolo,3 C. Palmeira,3 R. Adam, J. Roselló-Catafau.

    1Experimental Pathology, Instituto de Investigaciones Biomédicas de Barcelona, Barcelona, Catalonia, Spain; 2INSERM U935, Hôpital Paul Brousse, Paris, France; 3Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.

    Aldehyde dehydogenase (ALDH2) is a mitochondrial enzyme that recently has been involved in the cardioprotection against ischemia injury. No data are reported on the potential…
  • 2018 American Transplant Congress

    The Safety and Efficacy of Splenic Artery Ligation in Living Donor Liver Transplant Recipients

    Y. Gunay, S. Ganesh, M. Molinari, A. Tevar, C. Hughes, A. Humar.

    Surgery, University of Pittsburgh, Pittsburgh.

    Introduction: Portal hypertension in recipients undergoing living donor liver transplant (LDLT) is thought to be one of the main causes of posttransplant graft dysfunction. In…
  • 2018 American Transplant Congress

    The Initial Hepatic Artery Reperfusion versus Initial Portal Reperfusion in Liver Transplantation: Where Do We Stand?

    R. Shahbazov,1 F. Azari,3 J. Alejo,2 M. Talanian,2 M. Fox,2 K. Kennedy,2 S. Kessel,2 A. Nickkholgh,1 D. Maluf,1 S. Pelletier.1

    1Surgery, University of Virginia Health System, Charlottesville, VA; 2School of Medicine, University of Virginia Health System, Charlottesville, VA; 3Surgery, University of Pennsylvania Medical Center, Philadelphia, PA.

    Introduction: While initial portal vein reperfusion (PVRP) of a liver allograft is nearly standardized, limited data suggests initial hepatic arterial reperfusion (HARP) may improve hemodynamics…
  • 2018 American Transplant Congress

    Small-for-Size Grafts Increase Recurrence of Hepatocellular Carcinoma in Liver Transplantation beyond Milan Criteria

    E. Lee, S. Kim, J. Shim, J. Park, B. Na, S-.J. Park.

    Center for Liver Cancer, National Cancer Center, Goyang, Korea.

    BACKGROUND: Living donor liver transplantation (LDLT) has been reported to have high rates of hepatocellular carcinoma (HCC) recurrence compared to deceased donor liver transplant (DDLT).…
  • 2018 American Transplant Congress

    Hepatic Artery Resistive Indices on Doppler Ultrasound at Long Term Follow Up in Liver Transplant Recipients: Importance and Implications

    P. Serrano Rodriguez, L. Cramer, K. Jones, E. Lemmon, T. Masakadza, A. Milukas, R. Watkins, D. Gerber, C. Desai.

    Abdominal Transplant Surgery, The University of North Carolina, Chapel Hill, NC.

    Ultrasound Doppler has a proven value in early post transplant period, however the importance at the long term follow up is not proven. Doppler results…
  • 2018 American Transplant Congress

    Treatment and Outcomes of Orthotopic Liver Transplant Patients Secondary to Hepatitis C Virus: A Single Center Experience

    T. Chen,1 M. Moaddab,1 B. Pierce,1 R. Ghobrial.2

    1Department of Pharmacy, Houston Methodist Hospital, Houston, TX; 2Department of Surgery, Houston Methodist Hospital, Houston, TX.

    Background: Treatment of acute cellular rejection (ACR) in patients with orthotopic liver transplantation (OLT) secondary to hepatitis C virus (HCV) remains a major challenge due…
  • 2018 American Transplant Congress

    Isolated Right Hepatic Vein (RHV) Obstruction after Piggyback Liver Transplantation, an Infrahepatic Terminolateral Cavo-Cavostomy as a Rescue Technique to Save the Graft

    K. Pineda-Solis, C. Florez-Zorrilla, A. Sanchez-Cedillo, L. Ladrón de Guevara-Cetrina.

    Transplant Unit, National Medical Center "20 de Noviembre", Mexico City, Mexico.

    Background: The “piggyback” technique for liver transplantation (LT) has gained acceptance around the world. However, outflow problems are more common than the classic technique.Material and…
  • 2018 American Transplant Congress

    The Grade of Pre-Transplant Portal Vein Thrombosis in Liver Transplant Recipients Impacts Graft and Patient Survival

    M. Safwan, M. Sobolic, S. Nagai, R. Schilke, K. Collins, A. Yoshida, M. Abouljoud, M. Rizzari.

    Henry Ford Transplant Institute, Henry Ford Health System, Detroit, MI.

    Background: Portal vein thrombosis (PVT) in the pre-transplant (pretx) setting makes liver transplantation technically challenging and is also known to affect post transplant outcomes. Few…
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