Articles tagged "Liver grafts"

2022 American Transplant Congress
Comparative Analysis of Liver Organ Offers Pre- and Post- Acuity Circle Policy Change in the US
V. Reddy¹, R. Ruiz², H. Fernandez³, J. Bayer³, E. Martinez³, A. Gupta³, G. McKenna⁴, N. Onaca³, S. Lee³, T. Ma³, G. Testa³, A. Wall³
¹Baylor Scott and White Research Institute, Allen, TX, ²Baylor University Medical Center, Fort Worth, TX, ³Baylor University Medical Center, Dallas, TX, ⁴Baylor Simmons Transplant Inst, Dallas, TX
*Purpose: With the intended goal of reducing geographic inequities, the United Network for Organ Sharing (UNOS) and Organ Procurement and Transplantation Network (OPTN) transitioned to…
2022 American Transplant Congress
Final Report of the Use of α-Lipoic Acid in Liver Transplantation to Prevent Ischemia Reperfusion Injury
P. C. Casciato¹, N. Ambrosi², F. Caro², L. Oliveira¹, F. Zalazar¹, A. Garmendia¹, M. Bonifacio¹, M. Padilla¹, J. Paladini¹, J. Di Menno¹, J. Pekjol¹, E. de Santibañes¹, M. de Santibañes¹, G. Adrian¹, C. Incardona¹, E. Chuluyan²
¹Hospital Italiano, Buenos Aires, Argentina, ²CEFYBO, Buenos Aires, Argentina
*Purpose: The ischemia and reperfusion injury contributs to grafts deterioration and adverse post-transplant outcomes. The aim of the present study was to evaluate the safety…
2022 American Transplant Congress
Real-Time Application of Deep Learning in Diagnosis of Graft Fibrosis After Liver Transplantation Using Longitudinal Data
A. Azhie¹, D. Sharma², P. Sheth¹, W. Xu³, M. Bhat¹
¹Ajmera Transplant Program, University Health Network, Toronto, ON, Canada, ²Department of Biostatistics, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada, ³Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada
*Purpose: Graft fibrosis develops insidiously in liver transplant recipients and is associated with worse survival. Early detection of fibrosis is essential to avoid further progression…
2022 American Transplant Congress
Development of a Portable Device to Quantify Hepatic Steatosis in Donated Livers Using an AI Algorithm
S. Klinkachorn¹, C. J. Tsoi-A-Sue², R. R. Narayan², M. L. Melcher²
¹Computer Science, Stanford, Stanford, CA, ²Surgery, Stanford, Stanford, CA
*Purpose: An accurate estimation of liver fat content is necessary to predict how a donor liver will function after transplantation. This can be challenging at…
2022 American Transplant Congress
Gene Profiling to Distinguish Mechanisms of Liver Allograft Rejection and Acceptance in Cynomolgus Monkey
H. Sakai¹, E. Berglund¹, S. Chaudhry¹, Y. Kato¹, E. Duggan¹, J. Weiner¹, P. Alonso-Guallart¹, N. Llore¹, K. Brustle¹, J. Stern¹, B. Piegari¹, D. Ekanayake-Alper¹, M. Martinez², G. Pierre¹, M. Danton¹, S. Kofman¹, D. Ordanes¹, D. Hajosi¹, J. Lefkowitch³, A. Iuga¹, T. Kato⁴, A. Griesemer¹
¹Columbia Center for Translational Immunology, Columbia University, New York, NY, ²Department of Pediatrics, Columbia University, New York, NY, ³Departments of Pathology and Cell Biology, Columbia University, New York, NY, ⁴Department of Surgery, Columbia University, New York, NY
*Purpose: Liver is an immune regulatory organ. Spontaneous resolutions from rejection have been seen in our orthotopic cynomolgus monkey liver transplant models for tolerance induction…
2022 American Transplant Congress
End-to-Side Splenic to Hepatic Artery Reconstruction in Liver Transplant: A Case Series
N. Baker, L. Aviles-Ovalle, T. Baker, J. Campsen, R. Kim, G. Rofaiel
Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT
*Purpose: Optimal hepatic artery (HA) blood flow post-liver transplantation (LT) is necessary for long-term allograft success. HA thrombosis (HAT) contributes to significant morbidity and mortality…
2022 American Transplant Congress
Utilizing Microsurgeon Expertise in the Salvage of Hepatic Artery Dissection
R. Sitta¹, N. Ascher², J. Roberts², M. Piper³
¹General Surgery, UCSF, San Francisco, CA, ²Abdominal Transplant Surgery, UCSF, San Francisco, CA, ³Plastic and Reconstructive Surgery, UCSF, San Francisco, CA
*Purpose: Living donor hepatic artery intimal dissection is a rare but devastating complication often resulting in inability to utilize the graft. We detail the salvage…
2022 American Transplant Congress
Pretransplant microRNAs in Liver Perfusate Associate with Early Allograft Dysfunction
E. Bardhi, E. Williams, J. McDaniels, T. Rousselle, V. Mas, D. Maluf
University of Maryland School of Medicine, Baltimore, MD
*Purpose: Early allograft dysfunction (EAD) in liver transplantation (LT) is associated with poor long-term graft and patient survival. Prior to LT, while organs are stored…
2022 American Transplant Congress
Reality Capture Using Light Detection and Ranging 3D Photography of Liver Grafts for Volumetric Assessment: A Proof-of-Concept Preliminary Study
K. E. Karakasi¹, G. Katsanos², I. Karolos³, V. Tsioukas³, G. Tsoulfas⁴
¹University Transplantation Surgical Clinic, Heppocrateion General Hospital, Thessaloniki, Greece, ²Transplantation, Aristitle University of Thessaloniki, Thessaloniki, Greece, ³School of Runal and Surveying Engineering, Aristotle University of Thessaloniki, Thessaloniki, Greece, ⁴University Transplantation Surgical Clinic, Hippocrateion’ General Hospital of Thessaloniki, Thessaloniki, Greece
*Purpose: Reality capture uses various technical means to capture a digital 3D model representation of a subject from the real world. Whole liver graft volume…
2022 American Transplant Congress
Single Cell Multiomics Reveals Immune Mediators in Acute Cellular Rejection Following Pediatric Liver Transplantation
B. Rocque¹, D. Sarode², A. Barbetta³, P. Singh⁴, C. Goldbeck⁴, C. Weaver⁵, O. Akbari⁴, R. Kohli⁵, J. Emamaullee⁶
¹University of Southern California Keck School of Medicine, Los Angeles, CA, ²Keck School of Medicine of University of Southern California, Pasadena, CA, ³Surgery, abdominal transplat, University of Southern California, Los Angeles, CA, ⁴Keck School of Medicine of USC, Los Angeles, CA, ⁵Childrens Hospital Los Angeles, Los Angeles, CA, ⁶University of Southern California, Los Angeles, CA
*Purpose: Acute cellular rejection (ACR) is a common complication following pediatric liver transplantation with potential negative effects on allograft longevity. Currently, diagnosis and management are…

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