2017 American Transplant Congress
Molecular Adsorbent Recirculating System (MARS) Effectively Replaces Hepatic Function in Severe Acute Liver Failure.
Introduction:Patients with severe ALF have extreme physiologic dysfunction and often die if transplantation is not immediately available. Patients may be supported with MARS (R, Gambro)…2017 American Transplant Congress
Inflammation, Impaired Energy Metabolism and Synthetic Failure Characterize the Liver Transcriptome of End-Stage Idiopathic Pediatric Acute Liver Failure (PALF).
Background: PALF requiring liver transplantation (LTx) often has no known etiology, and could result from undiagnosed metabolic disorders. Mitochondrial dysfunction is common in PALF, but…2017 American Transplant Congress
Development and Validation of an FLF-Transplant Score to Predict Mortality of Patients with Fulminant Liver Failure.
The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
BACKGROUND & AIMS: We aimed to develop a simple prognostic model in predicting fulminant liver failure (FLF) patient mortality within 14 days after being listed…2017 American Transplant Congress
Liver Transplantation Beyond MELD 40.
Surgery, University of Maryland, Baltimore, MD
OBJECTIVE(S): Liver allocation is prioritized for the sickest patients; however, poorer liver transplant (LTx) outcomes are associated with increasing MELD scores. While MELD is capped…2017 American Transplant Congress
Simultaneous or Sequential Heart-Liver Transplantation Confer Superior Survival in Patients with Listed for Heart-Liver Transplantation: A National Analysis.
1Duke School of Medicine, Durham, NC; 2Dept of Surgery, Duke University Medical Center, Durham, NC
Background: Simultaneous heart-liver transplantation (TXP), for patients with combined heart and liver failure, confers survival benefit over remaining on the waitlist. Whether heart TXP followed…2017 American Transplant Congress
Substance Abuse in Acute Liver Failure: Time to Talk About Opiates.
Transplant Institute, Henry Ford Health System, Detroit
Purpose: Prescription opiate utilization is on the rise. Research on acute liver failure (ALF) has focused on acetaminophen (APAP) overdose or other medical etiologies but…2017 American Transplant Congress
Liver Retransplantation: The Largest Post MELD Single Center Experience.
Surgery, University of California Los Angeles, Los Angeles, CA
OBJECTIVE: Analyze post MELD liver retransplantation (Re-OLT) and identify recipient and donor preoperative risk factors associated with poor patient outcomes.BACKGROUND: Re-OLT is a high risk…2017 American Transplant Congress
Enhanced Liver Regeneration After Partial Hepatectomy in Mice Treated with a Prolyl Hydroxylase Inhibitor.
Purpose: Resection of more than 70% of liver mass increases incidence of post-operative hepatic failure due to an inability of the liver remnant to adequately…2017 American Transplant Congress
Liver Regeneration in Porcine Hepatectomy Model.
Department of Transplantation Surgery, Mayo Clinic, Rochester, MN
Background: Acute Liver Failure (ALF) is a serious condition. A substantial number of donor livers (10%) are used to save ALF patients. Supportive therapies such…2016 American Transplant Congress
High Efficacy of Ledipasvir/Sofosbuvir with Ribavirin in HCV Genotype-1 Infected Patients with Decompensated Liver Disease: Analysis by MELD Score from the SOLAR-1 and SOLAR-2 Trials.
Introduction: HCV infected patients with decompensated liver disease have significant morbidity & mortality. The efficacy & safety of LDV/SOF + RBV was evaluated in a…
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