Articles tagged "Liver cirrhosis"

2020 American Transplant Congress
Risk Prediction in the Meld-NA Era: The Tremendous Impact of Liver Related Complications
N. R. Mazumder¹, K. Atiemo², K. Jackson³, A. Daud⁴, A. Kho³, J. Levitsky¹, D. P. Ladner⁴
¹Gastroenterology and Hepatology, Northwestern University, Chicago, IL, ²Transplant Surgery, Tulane, New Orleans, LA, ³Center for Health Information Partnerships, Institute for Public Health and Medicine, Northwestern University, Chicago, IL, ⁴Transplant Surgery, Northwestern University, Chicago, IL
*Purpose: The MELD-Na score widely used for medical decision making but is not a good predictor of patient outcomes at low scores. Although portal hypertensive…
2020 American Transplant Congress
Live Donor Liver Transplant Offers Higher Survival, Improved Quality of Liver and Lower Morbidity for Recipients with Low MELD Score
M. Black, J. Bayer, H. Fernandez, E. Martinez, G. McKenna, N. Onaca, R. Ruiz, G. Testa, A. Wall, T. Ma, G. Saracino, S. Asrani, A. Gupta
Baylor University Medical Center, Dallas, TX
*Purpose: The shortage of cadaveric liver grafts contributes to significant waitlist mortality. Patients with low MELD-Na score (
2020 American Transplant Congress
Introducing the Smartphone App, EL-FIT (Exercise & Liver FITness), to Help Monitor and Prehabilitate Liver Transplant Candidates
A. Duarte-Rojo¹, P. M. Bloomer¹, R. J. Rogers², M. A. Dunn¹, E. B. Tapper³, R. Bataller¹, C. B. Hughes¹, A. A. Ferrando¹, W. R. Kim⁴, J. M. Jakicic²
¹University of Pittsburgh Medical Center, Pittsburgh, PA, ²University of Pittsburgh, Pittsburgh, PA, ³University of Michigan, Ann Arbor, MI, ⁴Stanford University, Palo Alto, CA
*Purpose: Physical activity is key to liver transplant (LT) prehabilitation, and leveraging technologies to monitor physical performance and to generalize training may be advantageous. EL-FIT…
2020 American Transplant Congress
The Relationship Between Frailty and Performance Status in Patients with Cirrhosis Awaiting Liver Transplantation
C. Q. Xu¹, F. Yao², Y. Mohamad², R. Wong², D. Kent², S. Seetharaman², Y. Srisengfa², J. C. Lai²
¹Department of Medicine, UCSF, San Francisco, CA, ²Division of Gastroenterology and Hepatology, Department of Medicine, UCSF, San Francisco, CA
*Purpose: Frailty—a multi-dimensional construct that encapsulates physical function, performance status, and nutritional status—has emerged as a critical determinant of mortality in patients with cirrhosis. Currently,…
2020 American Transplant Congress
2019 Refined Criteria for Cirrhotic Cardiomyopathy Predict Post Liver Transplant Cardiac Events
M. J. Izzy¹, A. Soldatova², X. Sun², M. Angirekula³, K. Mara⁴, G. Lin², K. Watt³
¹Gastroenterology and Hepatology, Vanderbilt University Medical Center, Nashville, TN, ²Cardiovascular Medicine, Mayo Clinic, Rochester, MN, ³Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, ⁴Health Sciences Research, Mayo Clinic, Rochester, MN
*Purpose: Cirrhotic cardiomyopathy (CCM) encompasses systolic ± diastolic dysfunction (DD) in patients with end stage liver disease in the absence of known cardiac disease. The…
2020 American Transplant Congress
Evolving Trends in Simultaneous Liver Kidney Transplant (SLKT) – Results from the US SLKT Consortium
G. Cullaro¹, J. Jo², J. Rassiwala², L. Van Wagner², R. Wong³, J. C. Lai³, J. Magee⁴, A. Schluger¹, P. Barman⁵, Y. Patel⁵, K. Walters⁶, S. Biggins⁶, P. Sharma⁴, E. C. Verna¹
¹New York Presbyterian, New York, NY, ²Northwestern University, Chicago, IL, ³UCSF, San Francisco, CA, ⁴University of Michigan, Ann Arbor, MI, ⁵Duke University, Durham, NC, ⁶University of Washington, Seattle, WA
*Purpose: The utilization of SLKT in the United States is rising in the MELD era. We aimed to understand the contemporary changes in characteristics and…
2019 American Transplant Congress
The Liver Frailty Index is Associated with Current and Subsequent Disability in Liver Transplant Candidates
J. C. Lai, J. L. Dodge, C. E. McCulloch, K. E. Covinsky, J. P. Singer
University of California, San Francisco, San Francisco, CA
*Purpose: The Liver Frailty Index (LFI) was developed to capture the effects of malnutrition and muscle wasting in patients with cirrhosis awaiting liver transplantation (LT).…
2019 American Transplant Congress
A Randomized Pilot Trial of Home-Based Physical Activity Plus Dietary Intervention to Improve Physical Function in Patients with Advanced Liver Disease
H. Chen¹, A. A. Ferrando², M. G. White², M. Pauly², T. Bartter², M. A. Dunn¹, W. R. Kim³, A. Duarte-Rojo¹
¹T.E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, ²University of Arkansas for Medical Sciences, Little Rock, AR, ³Stanford University, Palo Alto, CA
*Purpose: Deconditioning and frailty are prevalent among liver transplant (LTx) candidates and prehabilitation programs have been proposed in order to improve clinical outcomes. However, few…
2019 American Transplant Congress
Contribution of CD38 to Methionine Choline Deficient (MCD) Diet-Induced Liver Injury in Rats
J. Kim, Y. Lee, B. F. Reader, C. Akateh, K. R. Maynard, K. W. Washburn, J. L. Zweier, B. A. Whitson, S. M. Black
Department of Cardiac Surgery, The Ohio State Univ. Medical Center, Columbus, OH
*Purpose: Nonalcoholic fatty liver disease (NAFLD) and associated non-alcoholic steatohepatitis (NASH) is a rising cause of end stage liver disease, increasing the need for liver…
2019 American Transplant Congress
Personality Traits of Liver Transplant Candidates – Unappreciated Challenges
D. Ladner¹, J. Lai², A. N. Hall¹, E. D. Bastarache¹, A. Daud¹, T. Bogg³, A. Lebsack¹, T. Kalume¹, D. Mroczek¹
¹Northwestern University, Chicago, IL, ²UCSF, San Francisco, CA, ³Wayne State University, Chicago, IL
*Purpose: Liver transplant candidates are chronically ill, requiring complex medical care prior to and after transplant to optimize outcomes. Conscientiousness is one of the Big…

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