ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Liver cirrhosis"

  • 2020 American Transplant Congress

    The Therapeutic Potential of Human Liver-Derived Stem Cells Transplantation in Carbon Tetrachloride-Induced Rat Liver Cirrhotic Model

    S. Lee1, J. Lee2, H. Park2, Y. Kim2, S. Lee1

    1Department of Surgery, Samsung Medical Center, Seoul, Korea, Republic of, 2Stem Cell and Regenerative Medicine Center, Research Institute for Future Medicine, Samsung Medical Center, Seoul, Korea, Republic of

    *Purpose: Cirrhosis is a long-term consequence of chronic hepatic injury and there are no effective treatment methods. Mesenchymal stem cells (MSCs) have been reported to…
  • 2020 American Transplant Congress

    Declining Inpatient Mortality for Patients with Human Immunodeficiency Virus (HIV) and Cirrhosis: A Temporal Analysis of the Nationwide Inpatient Sample

    A. Kaplan, C. Lucero, B. Fortune, A. Jesudian, R. S. Brown Jr, R. Rosenblatt

    Weill Cornell Medicine, New York, NY

    *Purpose: Despite the advent of highly effective anti-retroviral therapy, HIV remains a major health burden. Though life expectancy has improved, patients are now dying from…
  • 2020 American Transplant Congress

    Frailty Attenuates the Gender Gap in Waitlist Mortality in Liver Transplant Candidates: A Multi-Center Study with 1,240 Patients with Cirrhosis

    J. C. Lai1, D. R. Ganger2, M. L. Volk3, J. L. Dodge1, M. A. Dunn4, A. Duarte-Rojo5, M. R. Kappus6, R. S. Rahimi7, D. Ladner2, B. Boyarsky8, M. McAdams-DeMarco8, D. L. Segev8, C. E. McCulloch1, E. Verna9

    1UCSF, San Francisco, CA, 2NW, Chicago, IL, 3Loma Linda Univ, Loma Linda, CA, 4UPMC, Pittsburgh, CA, 5UPMC, Pittsburgh, PA, 6Duke, Durham, NC, 7Baylor, Dallas, TX, 8JHMI, Baltimore, MD, 9Columbia, New York, NY

    *Purpose: Women LT candidates experience higher rates of waitlist mortality than men. Frailty is a critical determinant of mortality in patients with cirrhosis but it…
  • 2020 American Transplant Congress

    The Association between Infection and Important Clinical Outcomes in Acute-On-Chronic Liver Patients Admitted to ICU: A Single Center Cohort Analysis

    M. Kim1, A. Pawlowski2, R. G. Wunderink3, D. P. Ladner4, C. J. Karvellas5

    1Neurology, Northwestern University, Chicago, IL, 2Northwestern University, Chicago, IL, 3Medicine, Northwestern University, Chicago, IL, 4Surgery, Northwestern University, Chicago, IL, 5Medicine, University of Alberta, Edmonton, AB, Canada

    *Purpose: One of the most common precipitants of acute on chronic liver failure (ACLF) in cirrhotic patients is sepsis. We aimed to evaluate the relationship…
  • 2020 American Transplant Congress

    Karnofsky Performance Status Significantly Increases Waitlist Mortality among Different Grades of Acute on Chronic Liver Failure

    A. Ashhab1, R. Wong2, V. Sundaram1

    1Cedars Sinai Medical Center, Los Angeles, CA, 2Alameida Health System, Oakland, CA

    *Purpose: Acute on chronic liver failure (ACLF) is a condition associated with high waitlist mortality and graded according to the number of organ system failures…
  • 2020 American Transplant Congress

    Pre-Transplant Overt Hepatic Encephalopathy is Associated with Greater Cognitive Improvement after Liver Transplant

    M. Kim1, J. Menzel-Smith1, J. D. Peipert2, K. J. Reid1, P. Zee1, D. P. Ladner3

    1Neurology, Northwestern University, Chicago, IL, 2Northwestern University, Chicago, IL, 3Surgery, Northwestern University, Chicago, IL

    *Purpose: Persistent or residual cognitive impairment following liver transplant is frequently reported yet not well-characterized.*Methods: Cognitive function was tested in a prospective cohort of patients…
  • 2019 American Transplant Congress

    Early Renal Allograft Failure after Simultaneous Liver-Kidney Transplantation: Evidence for Utilization of the Safety Net

    G. Cullaro1, E. C. Verna2, B. J. Orandi3, J. C. Lai1

    1UCSF, San Francisco, CA, 2Columbia University, New York, NY, 3University of Alabama at Birmingham, Birmingham, AL

    *Purpose: Utilization of simultaneous liver-kidney transplant (SLKT) has increased dramatically during the Model for End-Stage Liver Disease (MELD) era. Prior studies have demonstrated a modest…
  • 2019 American Transplant Congress

    ALcohol Relapse after Liver Transplantation

    B. Movahedi, p. Mahboub, P. Martings, A. Bozorgzadeh

    Surgery, UMass Memorial Medical Center, Worcester, MA

    *Purpose: Alcoholic liver disease is a very common diagnosis among the patient’s population referred for liver transplantation. There are a number of different evaluation criteria…
  • 2019 American Transplant Congress

    Extreme Hyponatremia as a Risk Factor for Early Mortality after Liver Transplantation in the Model for End-Stage Liver Disease-Sodium Period

    H. Mouzaihem, M. Safwan, L. C. Chau, D. Moonka, M. Abouljoud, S. Nagai

    Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI

    *Purpose: While we reported that implementation of MELD-Na based liver allocation improved waitlist outcomes in patients with hyponatremia, its impact on post-transplant outcomes in this…
  • 2019 American Transplant Congress

    Targeting Syk Signaling in Myeloid Cells Protects against Liver Fibrosis and Hepatocarcinogenesis

    A. Torres-Hernandez, W. Wang, G. Miller

    Surgery, NYU School of Medicine, New York, NY

    *Purpose: The purpose of our study was to evaluate the mechanistic role of Spleen Tyrosine Kinase (SYK) signaling on the fibrosis - hepatocarcinogenesis axis and…
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