Articles tagged "LFA-1 antigen"

2018 American Transplant Congress
Ten Year Follow-Up of Islet Recipients on Anti-LFA1 Therapy: Over-Immunosuppression Leads to Operational Tolerance?
J. Gardner,¹ A. Posselt,¹ S. Wisel,¹ U. Mashirani,² G. Szot,¹ V. Nguyen,¹ K. Johnson,¹ J. McElroy,¹ Q. Tang,¹ P. Stock.¹
¹Surgery, University of California, San Francisco, San Francisco, CA; ²Endocrinology, University of California, San Francisco, San Francisco, CA.
Introduction: Ten-year outcomes from a cohort of five pre-uremic islet transplant (txp) recipients treated with anti-leukocyte functional antigen-1 (LFA-1) antibody Efalizumab (EFA) revealed two patients…
2015 American Transplant Congress
LFA-1 Is Crucial for Germinal Center Reconstruction After T cell Depletion and IL-21 Biased Antibody-Mediated Rejection
J. Kwun,¹ B. Oh,¹ H. Song,¹ A. Farris,¹ A. Kirk,² W. Mahle,¹ S. Knechtle.¹
¹Surgery, Emory Transplant Center, Atlanta, GA; ²Surgery, Duke University, Durham, NC.
[Background] Lymphocyte depletion prior to transplantation is beneficial in reducing initial maintenance immunosuppression in transplantation. However, despite its excellent efficacy in controlling T cell mediated…