Articles tagged "Kidney/pancreas transplantation"

2017 American Transplant Congress
Elevated Serum Lipase Levels in Simultaneous Pancreas and Kidney Transplantation May Indicate Anti-HLA Donor Specific Antibody Response.
B. Javaid, T. Raza, P. Abrams, S. Ghasemian, J. Moore, A. Gilbert, M. Grafals, J. Verbesey, M. Cooper.
Kidney and Pancreas Transplant Program, MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Georgetown University School of Medicine, Washington, DC
Background: Development of anti-HLA donor specific antibodies (DSAs) has been associated with inferior pancreas transplant outcomes. We analyzed data for pancreas and kidney transplant recipients…
2016 American Transplant Congress
Impact of Simultaneous Pancreas-Kidney Transplantation versus Kidney Transplant Alone on Patient and Graft Survival in Type 2 Diabetics with Elevated BMI.
S. Singh,^1,2 S. Kim.^1,2,3,4
¹Division of Nephrology, Department of Medicine, University of Toronto, Toronto, Canada; ²Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada; ³Division of Nephrology and the Multi-Organ Transplant Program, University Health Network, Toronto General Hospital, Toronto, Canada; ⁴Division of Nephrology and the Kidney Transplant Program, St. Michael's Hospital, Toronto, Canada.
Background: Simultaneous Pancreas-Kidney transplantation (SPKT) is becoming increasingly common in patients with Type 2 diabetes (T2DM). The BMI threshold for listing for SPKT in this…
2016 American Transplant Congress
How Did the New Kidney and Pancreas Allocation Systems Effect Pancreas Utilization in the First Six-Months?
R. Carrico,¹ J. Fridell,² J. Odorico,³ Z. Stewart.⁴
¹UNOS, Richmond, VA; ²Indiana Univ School of Medicine, Indianapolis, IN; ³Univ of Wisconsin Hospital and Clinics, Madison, WI; ⁴Univ of Iowa Hospital and Clinics, Iowa City, IA.
Background: In 2010 a new pancreas allocation system (PAS) was approved by the OPTN and implemented in October 2014, shortly preceding the new kidney allocation…
2016 American Transplant Congress
Influence of Pancreas Import and Cold Ischemia on Outcomes Following Pancreas Transplantation.
M. Khan,¹ H. El-Hennawy,¹ J. Rogers,¹ A. Farney,¹ G. Orlando,¹ A. Reeves-Daniel,² A. Palanisamy,² R. Stratta.¹
¹Surgery, Wake Forest, Winston-Salem, NC; ²Internal Medicine, Wake Forest, Winston-Salem, NC.
Proposed changes in pancreas transplant (PT) allocation may improve organ sharing but increase cold ischemia time (CIT). Methods: We performed a single center, retrospective study…
2016 American Transplant Congress
Simultaneous Pancreas and Kidney Transplantation for Type 2 Diabetes.
K. Wong, W. Bry, H. Mahanty, P. Patel.
Transplantation, California Pacific Medical Center, San Francisco, CA.
Introduction: Type 2 diabetes (T2DM) is characterized initially by insulin resistance and later by beta cell failure. Historically, T2DM has been a relative contraindication for…
2016 American Transplant Congress
Is Delayed Graft Function in Simultaneous Kidney-Pancreas Transplant Recipients Associated with an Increased Risk of Pancreas Graft Failure?
S. Singh,^1,2 S. Kim.^1,2,3,4
¹Division of Nephrology, Department of Medicine, University of Toronto, Toronto, Canada; ²Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada; ³Division of Nephrology and the Multi-Organ Transplant Program, University Health Network, Toronto General Hospital, Toronto, Canada; ⁴Division of Nephrology and the Kidney Transplant Program, St. Michael's Hospital, Toronto, Canada.
Background: Delayed graft function (DGF) in kidney transplant recipients is associated with adverse short and long-term outcomes. However, the impact of DGF of the kidney…
2016 American Transplant Congress
Everolimus in Combination with Reduced Dose Tacrolimus Is Effective as a Prophylaxis of Acute Rejection in Low-to-Moderate Immunologic Risk De Novo Kidney Transplantation Patients.
Y. Qazi, F. Shihab, S. Mulgaonkar, K. MaCague, D. Patel.
University of Southern California, Los Angeles; University of Utah, Salt Lake City; Barnabas Health, West Orange; Novartis Pharmaceuticals Corporation, East Hanover.
The US92 study determined whether, in de novo renal transplant patients (pts), concentration-controlled everolimus (EVR) with reduced dose tacrolimus (RTAC) is non-inferior compared to CellCept®…
2016 American Transplant Congress
Concordance Between Pancreatic Rejection and Kidney Rejection and Kidney Survival in Simultaneous Pancreas Kidney Transplantation.
I. Moinuddin, T. Taber, M. Yaqub, D. Mishler, O. Adebiyi, J. Chen, M. Goble, J. Powelson, J. Fridell, A. Sharfuddin.
Transplant Nephrology, Indiana University, Indianapolis, IN.
Purpose: It is not known whether pancreas rejection is associated with increased kidney rejection. Also, it is not known whether pancreas survival affects kidney and…
2016 American Transplant Congress
Plasma Alemtuzumab Levels Show Great Interpatient Variability, but Are Not Associated with Late Acute Rejection in Simultaneous Pancreas-Kidney Recipients.
J. Bank,¹ M. Mallat,¹ C. Jol-van der Zijde,² R. Bredius,² P. van der Boog,¹ A. Braat,³ J. Ringers,³ M. Reinders,¹ J. de Fijter.¹
¹Nephrology, LUMC, Leiden, Netherlands; ²Pediatrics, LUMC, Leiden, Netherlands; ³Surgery, LUMC, Leiden, Netherlands.
Introduction: Alemtuzumab induction followed by a steroid-free, tacrolimus (Tac) and mycophenolate mofetil (MMF) based regimen effectively prevented acute rejection after simultaneous pancreas-kidney transplantation (SPKT). Acute…
2016 American Transplant Congress
Duodenal Graft Complications After Pancreas Transplant: Evolving Management.
D. Al-Adra,¹ J. Laurence,² A. Norgate,¹ N. Goldaracena,¹ M. Marquez,¹ A. Barbas,¹ M. Dib,¹ M. Selzner,¹ M. Cattral.¹
¹Department of Surgery, Toronto General Hospital, University of Toronto, Toronto, ON, Canada; ²Royal Prince Alfred Institute of Academic Surgery, University of Sydney, Sydney, New South Wales, Australia.
Introduction Pancreas transplantation is an established treatment for insulin-dependent-diabetes-mellitus with renal failure. However, complications relating to the transplant duodenum remain a significant cause of morbidity…