2021 American Transplant Congress
Outcomes of Hepatitis C Nucleic Acid Testing Positive Donors in Aviremic Recipients With Delayed Direct-Acting Antiviral Initiation
Pharmacy, Tampa General Hospital, Tampa, FL
*Purpose: The purpose of this study was to assess the clinical impact of utilizing hepatitis C virus (HCV) nucleic acid testing (NAT)+ donors in HCV…2021 American Transplant Congress
Chances of Renal Recovery in Liver Only Transplant Recipients Who Were Eligible for Simultaneous Liver-Kidney Transplant
*Purpose: Progressive decline in renal function is common among patients with end-stage liver disease. Liver transplant (LT) candidates can often develop severely impaired renal function…2021 American Transplant Congress
Donor Service Area Characteristics Impacting Liver and Kidney Deceased Donor Population
Surgery, -University of Florida, Gaiinesville, FL
*Purpose: While there is ample evidence of racial and ethnic disparities in access to the waitlist, being transplanted, and post-transplant outcomes in liver and kidney…2021 American Transplant Congress
Highly Sensitized Simultaneous Liver-kidney Transplant Recipients Show a Reduction in Panel Reactive Antibodies and No Kidney Rejection 1-year Post-transplant
Houston Methodist Hospital, Houston, TX
*Purpose: The liver is unique in that it is considered an immunologically tolerant organ against graft destruction by antibodies. Simultaneous liver-kidney transplantation (SLKT) are often…2021 American Transplant Congress
Src Kinase Inhibitor Pp1 Blunts Tgf-β1 Dependent Endothelial‐to‐Mesenchymal Transition to Alleviate Allograft Kidney Fibrosis Through Orchestrating β-catenin Signaling
Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
*Purpose: Allograft fibrosis is an important contributor to graft loss in chronic renal allograft injury. Endothelial‐to‐mesenchymal transition (EndMT), dysfunction of endothelial cells, played a vital…2021 American Transplant Congress
A Comparison Between Combined Liver Kidney Transplants to Liver Transplants Alone: A Systematic Review and Meta-analysis
*Purpose: Since the introduction of the Model for End-stage Liver disease (MELD) criteria in 2002, more combined liver kidney transplants are performed. Until 2017, no…2021 American Transplant Congress
Regulatory Macrophage Induced by Il-33 Promoted Immune Tolerance of Kidney Transplantation Through Siglec-10
Urology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China
*Purpose: Acute and chronic rejection are key problems in renal transplantation. It is ideal to induce immune tolerance to suppress rejection while regulatory macrophages (Mregs)…2021 American Transplant Congress
Use of Immune Checkpoint Inhibitors in Solid Organ Transplant Recipients: A Scoping Review
University of Missouri, Columbia, MO
*Purpose: Immune checkpoint inhibitors (ICI) are an emerging treatment for numerous advanced diseases, but their safety and efficacy in immunosuppressed transplant patients is not known.…2021 American Transplant Congress
Effect of Defibrotide on Kidney Ischemia Reperfusion Injury in a Preclinical Renal Transplant Model
*Purpose: Ischemia reperfusion injury (IRI) is a major contributor to graft failure. During organ removal and preservation, ischemia results in anaerobic respiration and cellular damage.…2021 American Transplant Congress
SARS-CoV-2 Infection in Solid Organ Transplant Recipients: A Retrospective Cohort Study
Infectious Diseases, University of Massachusetts, Worcester, MA
*Purpose: Initial studies of COVID-19 in solid organ transplant (SOT) recipients demonstrated high mortality rates, but more recent comparative data shows contradictory results.*Methods: We evaluated…
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