Articles tagged "Kidney/liver transplantation"

2019 American Transplant Congress
Allograft Quality Impacts Simultaneous Liver Kidney Transplant Survival Outcomes in Recipients That Undergo Liver Re-Transplantation
J. Reyes, M. Eerhart, C. Blanton, P. Chlebeck, E. Polyak, Y. Yankol, L. Fernandez
Department of Surgery, University of Wisconsin - Madison, Madison, WI
*Purpose: The only effective therapeutic strategy for irreversible liver graft failure is re-transplantation. The impact of liver and kidney quality in secondary SLK (sSLK) survival…
2019 American Transplant Congress
The Clinical & Economic Impact Of Allosensitization In Liver Alone And Simultaneous Liver Kidney Transplantation
M. Askar¹, G. Saracino¹, A. Elsabbagh², J. Fung³, T. Srinivas⁴, S. Flechner⁵, J. Trotter¹, G. Testa¹, B. Kaplan⁶, G. Klintmalm¹, J. Schold⁵, S. Asrani¹
¹Transplant Center, Baylor Scott & White, Dallas, TX, ²St. Vincent Health, Indianapolis, IN, ³University of Chicago Medicine, Chigao, IL, ⁴Intermountain Healthcare, Salt Lake City, UT, ⁵Cleveland Clinic, Cleveland, OH, ⁶Transplant Center, Baylor Scott & White, Temple, TX
*Purpose: Allosensitization is thought to have marginal impact among patients that undergo liver transplantation (LTA); further among simultaneous liver kidney transplantation (SLKT), livers may protect…
2019 American Transplant Congress
Staged Procedure In Simultaneous Liver And Kidney Transplant -the “Swedish” Experience
A. Gravetz
Transplant Surgery, Swedish Medical Center, Seattle, WA
*Purpose: As many as 30% of liver transplant candidates have renal insufficiency requiring a combined liver and kidney transplantation. The prolonged and complex simultaneous liver-kidney…
2019 American Transplant Congress
Intra-Operative Kinetics of Anti-HLA Antibodies in Simultaneous Liver-Kidney Transplantation
M. Kueht, P. Jindra, M. Cusick, N. Galvan, A. Rana, J. Goss
Baylor College of Medicine, Houston, TX
*Purpose: In simultaneous liver-kidney transplantation (SLKT) in highly-sensitized patients, donor specific anti-HLA antibodies (DSA) can be present prior to transplant leading to positive crossmatch, yet…
2019 American Transplant Congress
Donor-Derived Cell-Free DNA in Urine Identifies BKVN with Graft Injury in BK Viruria Kidney Transplant Recipients
G. Huang¹, X. Chen¹, S. Yang², W. Chen², P. Chen³, X. Hou⁴, T. Jiang⁵, H. Liu⁵, X. Li⁵, C. Wang¹
¹Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ²Department of Pathology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ³Department of clinical laboratory, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ⁴Guangzhou KingMed Center for Clinical Laboratory Co.,Ltd., Guangzhou, China, ⁵Research and Development, AlloDx Biotech Co.Ltd., Suzhou, China
*Purpose: BK Polyomavirus nephropathy (BKVN) is an important cause of dysfunction and failure of renal transplants. Elevated levels of donor-derived cell-free DNA (dd-cfDNA) in the…
2019 American Transplant Congress
Outcomes of En Bloc Simultaneous Liver-Kidney Transplantation Compared to the Traditional Technique
A. R. Cortez, T. C. Lee, A. Kassam, M. C. Morris, L. K. Winer, L. Sage Silski, M. C. Cuffy, T. S. Diwan, R. C. Quillin, S. A. Shah
University of Cincinnati, Cincinnati, OH
*Purpose: Simultaneous liver-kidney transplantation (SLKT) is indicated for patients with end-stage liver disease (ESLD) and concurrent renal insufficiency. En bloc SLKT has been reported as…
2019 American Transplant Congress
Bortezomib Attenuates the Progression of Epithelial to Mesenchymal Transition through Smurf1 Akt mTOR P70S6K Pathway in Rat Allograft Renal Interstitial Fibrosis Model
R. Tan, Z. Wang, S. Fei, Z. Han, J. Tao, X. Ju, M. Gu
No.300 Guangzhou Road of Nanjing, Nanjing, China
*Purpose: Our study was to detect the effects of Bortezomib and Smurf1 in the EMT and allograft renal interstitial fibrosis.*Methods: Biomarkers of EMT, as well…
2018 American Transplant Congress
A Medical Decision Analysis for the Use of Donation after Cardiac Death Donors for Simultaneous Liver-Kidney Transplant
A. Miller, K. Tennankore, B. Kiberd.
Division of Nephrology, Department of Medicine, Dalhousie University, Halifax, NS, Canada.
For patients on the simultaneous liver-kidney transplant (SLKT) waitlist, acceptance of donation after cardiac death (DCD) organs may facilitate earlier transplantation thereby reducing waitlist mortality,…
2018 American Transplant Congress
Association between Genetic Polymorphisms of Fc Gamma Receptor Genes (FcgR) and the Development of Donor Specific Antibodies (DSA) after Kidney Transplant
D. Min,¹ Y. Chang,² T. Shah.³
¹College of Pharmacy, Western University of Health Sciences, Pomona, CA; ²National Institute of Transplantation Foundation, Los Angeles, CA; ³Multi-Organ Transplant Center, St. Vincent Medical Center, Los Angeles, CA.
Background: Antibody mediated rejection (AMR) is one of the most important barriers to improve long-term kidney transplant outcomes. The presence of donor specific antibodies (DSA)…
2018 American Transplant Congress
Disparate Candidate Selection Practices and Substantial Use of Low KDPI Kidneys in Combined Heart-Kidney and Liver-Kidney Transplantation, 2012-2016
R. Steiner,¹ J. Halldorson.²
¹Transplant Nephrology, University of California at San Diego School of Medicine, San Diego, CA; ²Transplant Surgery, Sharp Memorial Hospital/Balboa Nephrology, San Diego, CA.
Transplant professionals have struggled to formulate defensible standards for combined heart-kidney and liver-kidney transplantation (HKTs and LKTs). In these recipients, recovery of native renal function…