Articles tagged "Kidney/liver transplantation"

2019 American Transplant Congress
CMV-Specific Cell-Mediated Immunity Early after Transplantation Discriminates R+ Transplant Patients at Risk of CMV Infection among Different Solid Organ Transplants
M. Jarque¹, A. Cachero², E. Garcia-Romero³, L. Lladó², C. Baliellas², C. Diez³, E. Melilli⁴, J. Fabregat², J. Gonzalez-Costello³, O. Bestard⁴
¹Experimentall Nephrology laboratory, IDIBELL, L'Hospitalet de Llobregat. Barcelona, Spain, ²Liver Transplant Department, Bellvitge University Hospital, L'Hospitalet de Llobregat. Barcelona, Spain, ³Heart Transplant Unit, Cardiology Department, Bellvitge University Hospital, L'Hospitalet de Llobregat. Barcelona, Spain, ⁴Kidney Transplantation Unit, Bellvitge University Hospital- IDIBELL, L'Hospitalet de Llobregat. Barcelona, Spain
*Purpose: While monitoring CMV-specific cell-mediated immunity(CMI) has shown to be effective in predicting the risk of CMV infection, comparisons across different solid organ transplants(SOT) and…
2019 American Transplant Congress
Safety and Efficacy of Anti Xa Inhibitors Post-Transplant with Concomitant Calcineurin Inhibitors
K. A. McMurry¹, J. Shuster², K. Bain², T. Horwedel³, J. Hartupee²
¹Michigan Medicine, Ann Arbor, MI, ²Barnes-Jewish Hospital, St. Louis, MO, ³Veloxis Pharmaceuticals, Cary, NC
*Purpose: Despite demonstrated benefits of Anti-Xa Inhibitors (ATIs) in the general population, ATIs have not gained uniform acceptance in SOT due to lack of supportive…
2019 American Transplant Congress
Impact Of Delayed Kidney Transplantation On Positive Crossmatch Liver Kidney Transplantation
Z. Rokop, C. Kubal, B. Ekser, R. Mangus, J. Fridell, P. Mihaylov, W. Goggins
Department of Surgery, Indiana University Hospital, Indianapolis, IN
*Purpose: Kidney transplantation in sensitized patients is associated with an increased immunological risk. Significant decrease in circulating anti-HLA donor specific antibodies (DSA) has been observed…
2019 American Transplant Congress
CD19⁺Tim-1⁺ Regulatory B Cells Mediate the Balance of Th17 Treg to Decrease the Level of Donor-Specific Antibodies in Mice Secondary Skin Transplantation Model
Z. Wang, S. Fei, H. Chen, L. Sun, Z. Han, J. Tao, X. Ju, R. Tan, M. Gu
No.300 Guangzhou Road of Nanjing, Nanjing, China
*Purpose: In this study, we were aimed to explore the potential influence of CD19+Tim-1+ Regulatory B cells (Bregs) on the production of DSAs in a…
2019 American Transplant Congress
CNV Screening For End-stage Renal Disease
C. E. Fishman, B. Chang, A. Shaked, B. J. Keating
Surgery, University of Pennsylvania, Philadelphia, PA
*Purpose: The prevalence of ESRD in the United States was 2,160.7 cases per one million individuals in 2016, and a primary cause of ESRD was…
2019 American Transplant Congress
Correlation between Self-Reported Medication Adherence and Side Effects in Transplant Recipients
T. Harrison¹, K. Foster¹, N. Patel¹, H. Meadows¹, C. Perez¹, H. Corbo¹, J. Fleming¹, N. Pilch¹, D. DuBay², J. McGillicuddy², S. Nadig², V. Rohan², D. Taber¹
¹Pharmacy Services, Medical University of South Carolina, Charleston, SC, ²Transplant Surgery, Medical University of South Carolina, Charleston, SC
*Purpose: Medication non-adherence (MNA) is a major risk factor for acute rejection and graft loss amongst all organ groups. It is unclear how medication side…
2019 American Transplant Congress
Impact of Cytomegalovirus on the Immune System of Healthy Humans
W. Zhang, J. Robertson, G. Karadkhele, B. Johnson, C. Larsen
Emory Transplant Center, Emory University, Atlanta, GA
*Purpose: CMV is a frequent pathogen after transplantation. 2/3 of recipients harbor latent CMV and are at moderate risk. CMV- recipients divide into high or…
2019 American Transplant Congress
AMD3100 and Low-Dose FK506 Prevent De Novo Donor Specific Antibody Formation and Rejection in a Sensitized Kidney Transplantation Model
A. R. Ahmadi, L. Qi, R. N. Wesson, A. M. Cameron, Z. Sun
Johns Hopkins University School of Medicine, Baltimore, MD
*Purpose: De novo donor specific antibody (DSA) formation and antibody mediated rejection (AMR) are the main cause of allograft failure long-term. We have developed a…
2019 American Transplant Congress
HOPE Act Deceased Donors Referrals: Barriers to Donation
O. Kusemiju, C. Durand, B. Doby, M. Bowring, B. Barnaba, W. Werbel, D. Brown, A. Tobian, S. Seaman, D. Ostrander, D. Segev
Johns Hopkins University, Baltimore, MD
*Purpose: HIV+ deceased donors (D+) represent a unique resource for HIV+ recipients but HIV D+ may have medical contraindications to donation or lower authorization rates.…
2019 American Transplant Congress
Stakeholder Perspectives in Peer Mentoring Program for Pediatric Solid Organ Transplant Recipients
C. Strachan, M. Paton, J. Reason, S. Amaral
Nephrology, Children's Hospital of Philadelphia, Philadelphia, PA
*Purpose: This study analyzed feedback surveys from Peers4PATH, a peer mentoring program, aimed to improve medication adherence and health related quality of life (HRQOL) in…