Articles tagged "Kidney"

2016 American Transplant Congress
Positive Impact of a Pilot Pharmacist-Run Diabetes Pharmacotherapy Clinic in Solid Organ Transplant Recipients.
D. Newland, A. Edwards, R. Hall, P. Maxwell.
University Transplant Center, University Health System and The University of Texas Health Science Center at San Antonio, San Antonio, TX.
Background: Post-transplant diabetes mellitus (PTDM) can lead to significant morbidity and cardiovascular death with a functioning graft. A paucity of literature exists regarding glycemic control…
2016 American Transplant Congress
Signs of a Dying Organ: Beyond Resistance in Subnormothermic Kidney Perfusion.
M. Blum, D. Urcuyo, Q. Liu, B. Soliman, T. Okamoto, D. Goldfarb, C. Quintini.
Cleveland Clinic, Cleveland, OH.
Purpose: In hypothermic machine preservation of the kidney, resistance is often used to assess organ quality. Since no prognostic standard yet exists for subnormothermic ex-vivo…
2016 American Transplant Congress
Hydrogen Sulphide Is an Important Regulator of Erythropoietin Synthesis in Patients with Anemia of Chronic Kidney Disease.
J. Leigh,¹ P. Shao,¹ M. Saha,¹ I. Lobb,¹ A. Pasch,⁵ H. van Goor,⁴ M. Feelisch,² R. Wang,³ A. Sener.¹
¹Western University, London, Canada; ²University of Southhampton, Southhampton, United Kingdom; ³Lakehead University, Thunder Bay, Canada; ⁴University of Gronigen, Groningen, Netherlands; ⁵University Hospital Bern, Bern, Switzerland.
Anemia affects 90% of hemodialysis patients and is a tremendous concern for patients and health care providers. CKD leads to chronic interstitial fibrosis which leads…
2016 American Transplant Congress
ER Stress and Loss of GRP78 Expression Provides a Link Between Renal Ischemia/Reperfusion Injury and the Urinary Metabolome.
C. van Kooten,¹ T. Pacchiarotta,² P. van der Pol,¹ J. de Fijter,¹ N. Schlagwein,¹ D. van Gijlswijk,¹ O. Mayboroda.²
¹Nephrology, Leiden University Medical Center, Leiden, Netherlands; ²Centre for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, Netherlands.
Ischemia/reperfusion injury (IRI) profoundly impacts graft survival following kidney transplantation. Epithelial injury is one of the earliest histological alterations of IRI and is especially observed…
2016 American Transplant Congress
Acute Allograft Glomerulopathy: A Distinct Form of Cellular Rejection.
O. AL-Badri, M. Alexander, F. Cosio, L. Cornell.
Mayo Clinic, Rochester, MN.
Background: Acute allograft glomerulopathy (AAG) is an unusual glomerular lesion of allografts with endocapillary hypercellularity, markedly enlarged endothelial cells occluding the capillary lumen, and absence…
2016 American Transplant Congress
The First 48 Months of an Australian Renal and Liver Organ Transplant Dermatology Database.
L. Ge,^1,2 P. Lowe.^1,2
¹Department of Dermatology, Royal Prince Alfred Hospital, Sydney, NSW, Australia; ²Faculty of Medicine, University of Sydney, Sydney, NSW, Australia.
PurposeThere have been few studies of non-melanoma skin cancers in the Australian cohort, a population unique for its high ambient UV radiation and sun-long lifestyle.…
2016 American Transplant Congress
Health Insurance Trends in United States Living Kidney Donors.
J. Rodrigue,^1,2 A. Fleishman.¹
¹Surgery, Beth Israel Deaconess Medical Center, Boston, MA; ²Surgery, Harvard Medical School, Boston, MA.
The aim of this study was to examine health insurance trends in living kidney donors (LKDs) in the United States and their association with donor…
2016 American Transplant Congress
Analysis of a Large Single-Center Cohort of Renal Transplant Recipients with Histoplasmosis.
M. Mashayekhi, A. Langone.
Internal Medicine, Vanderbilt University Medical Center, Nashville, TN.
The dimorphic fungus Histoplasma capsulatum is endemic along the Ohio and Mississippi River Valleys and can cause clinically significant disease in those with impaired cellular…
2016 American Transplant Congress
Molecular Diagnosis of Antibody-Mediated Rejection in Routine Formalin-Fixed Paraffin-Embedded Nonhuman Primate Renal Allograft Biopsies.
B. Adam,¹ I. Rosales,² T. Oura,² R. Smith,² A. Cosimi,² T. Kawai,² R. Colvin,² M. Mengel.¹
¹University of Alberta, Edmonton, Canada; ²Harvard Medical School and Massachusetts General Hospital, Boston.
Background: In 2013, the Banff classification proposed molecular testing as an adjunct for the diagnosis of antibody-mediated rejection (ABMR) in renal allografts. We analyzed whether…
2016 American Transplant Congress
A Quantitative CD45 Assay May Improve Diagnostic Accuracy of the Diagnosis of Acute Cellular Rejection in Transplant Kidney Biopsies.
L. Laszik, S. Bowman, V. Walavalkar, F. Vincenti, Z. Laszik.
UCSF, San Francisco.
Purpose: We have previously shown that the total inflammatory load in transplant kidney biopsies (TxBx) can be determined with a high degree of accuracy using…