Articles tagged "Kidney"

2016 American Transplant Congress
Kidney Retransplantation Is Associated with Higher Mortality Risk Among HIV+ vs. HIV- Recipients.
B. Shelton,¹ S. Mehta,¹ D. Sawinski,² R. Reed,¹ P. MacLennan,¹ S. Gustafson,³ C. Durand,⁴ D. Segev,⁴ J. Locke.¹
¹School of Medicine, University of Alabama at Birmingham, Birmingham, AL; ²School of Medicine, University of Pennsylvania, Philadelphia, PA; ³Scientific Registry of Transplant Recipients, Minneapolis, MN; ⁴School of Medicine, Johns Hopkins University, Baltimore, MD.
Background: Excellent outcomes have been demonstrated in HIV+ kidney transplant (KT) recipients, yet no study has explored outcomes among HIV+ reKT recipients.Methods: 4,683 adult reKT…
2016 American Transplant Congress
Randomized Controlled Study Evaluating Adherence Monitoring with Electronic Feedback on Reducing Renal Allograft Rejection.
A. Bodzin, Y. Becker, M. Josephson, P. Witkowski, M. Lockwood, L. Potter, B. Kane, L. Lourenco, J. Millis.
Transplant Center, University of Chicago, Chicago, IL.
Purpose: The negative impact of non-adherence to the immunosuppressant medication (IM) regimen on transplant outcomes is well recognized. In an attempt to improve outcomes, the…
2016 American Transplant Congress
Outcomes of Donor Nephrectomy (DN) in the Obese.
O. Serrano,¹ A. Bangdiwala,² D. Vock,³ E. Minja,¹ W. Payne,¹ T. Dunn,¹ S. Chinnakotla,¹ E. Finger,¹ T. Pruett,¹ A. Matas,¹ R. Kandaswamy.¹
¹Surgery, Univ. of Minnesota, Minneapolis, MN; ²Biostatistics and Bioinformatics Core, Masonic Cancer Center, Minneapolis, MN; ³Biostatistics, Univ. of Minnesota, Minneapolis, MN.
PURPOSE: In an effort to address the critical organ shortage and rising obesity rates, the criteria for live kidney donation (LKD) have been expanded to…
2016 American Transplant Congress
A Randomized-Controlled Trial Comparing the Efficacy of CYP3A5 Genotype-Based with Bodyweight-Based Tacrolimus Dosing After Living Donor Kidney Transplantation.
N. Shuker,^1,2 R. Bouamar,² R. van Schaik,³ M. Clahsen -van Groningen,⁴ J. Damman,⁵ C. Baan,¹ J. van de Wetering,¹ A. Rowshani,¹ W. Weimar,¹ T. van Gelder,^1,2 D. Hesselink.¹
¹Internal Medicine, Erasmus Medical Centre, Rotterdam, Netherlands; ²Hospital Pharmacy, Erasmus Medical Centre, Rotterdam, Netherlands; ³Clinical Chemistry, Erasmus Medical Centre, Rotterdam, Netherlands; ⁴Pathology, Erasmus Medical Centre, Rotterdam, Netherlands; ⁵Pathology, Academic Medical Centre, Amsterdam, Amsterdam, Netherlands.
Patients expressing the cytochrome P450 (CYP) 3A5 gene require a higher tacrolimus dose to achieve therapeutic exposure compared with non-expressers. This randomized-controlled study investigated if…
2016 American Transplant Congress
Bioinformatic Analysis of Pathways Mediating Clusterin Functions in Kidney Cells Under Normoxia and Hypoxia.
G. Dairi, Q. Guan, C. Collins, C. Ong, M. Gleave, C. Nguan, C. Du.
Department of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada.
Background: Clusterin (CLU) is a chaperone-like protein and contributes to the resistance of the kidney to ischemia-reperfusion injury (IRI), however its pathways are not fully…
2016 American Transplant Congress
Pre-Transplant Anti-A Titers in Waitlisted A2 to B Kidney Transplant Candidates.
D. Moore, I. Feurer, R. Forbes, A. DeMers, D. Shaffer.
Vanderbilt University, Nashville, TN.
Introduction:The KAS allocates A2 and A2B donor kidneys to blood type B candidates. Research is limited and variability exists among centers regarding the significance, relevance,…
2016 American Transplant Congress
Distinct Phenotype and Function of Plasmacytoid Dendritic Cells from Kidney Allografts in Tolerant Recipients.
N. Oh,^1,2 C. Yang,^1,2,3 M. Tonsho,^1,2 D. Ndishabandi,^1,2,3 P. Russell,^1,2 R. Colvin,^1,3 J. Madsen,^1,2 A. Alessandrini.^1,2
¹Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA; ²Department of Surgery, Massachusetts General Hospital, Boston, MA; ³Department of Pathology, Massachusetts General Hospital, Boston, MA.
BACKGROUND: Cellular infiltrates in kidney allografts may be relevant to the induction or maintenance of regulatory tolerance. Here we examined the phenotype, anatomical distribution and…
2016 American Transplant Congress
Potential Kidney Donors with Asymptomatic Micorsocpic Hematuria: Histopathological Findings & Outcomes.
E. Hassan,^1,2 H. Aleid,¹ T. Zulfiquar,¹ I. Ibrahim,^1,3 H. Almana.⁴
¹Department of Kidney & Pancreas Transplantation, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia; ²Department of Nephrology, Fayoum University, Fayoum, Egypt; ³Department of Nephrology, Cairo University, Cairo, Egypt; ⁴Department of Anatomic Pathology, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.
Background: Microscopic hematuria is not uncommon in potential kidney donors. After excluding urological causes, most of these donors require kidney biopsy to exclude glomerular lesions.…
2016 American Transplant Congress
Establishing a Learning Curve for Laparoscopic Living Donor Nephrectomy.
Z. Ahmed, R. Tamburrini, R. Uwechue, P. Chandak, F. Calder, N. Kessaris, N. Mamode.
Abdominal Transplant Unit, Guy's Hospital, London, United Kingdom.
Despite thousands of hand assisted laparoscopic donor nephrectomies (HALDNs) having been performed a paucity of data still exists in establishing how many procedures are required…
2016 American Transplant Congress
Quantitative Hepatitis C Virus (HCV) RNA in Plasma and Kidney Tissue in HCV Antibody Positive Donors.
H. Shike,¹ Z. Kadry,² R. Shah,² Y. Imamura,¹ W. Greene,¹ J. Gaspari,¹ T. Riely,¹ H. Nathan,³ R. Hasz,³ A. Jain.¹
¹Surgery, Transplant, Hershey Medical Center, Hershey, PA; ²Pathology, Hershey Medical Center, Hershey, PA; ³OPO, Gift of Life Donor Program, Philadelphia, PA.
Background: Currently HCV antibody positive deceased donors renal allografts are not considered for transplantation in HCV negative recipients. With recent development of anti-HCV therapy, utilization…