Articles tagged "Kidney"

2017 American Transplant Congress
The Use of a Furosemide Stress Test (FST) for Assessment of Discarded Deceased Donor Kidneys in an Ex-Vivo Normothermic Perfusion Model.
I. Palma, Y. Smolin, S. Kabagambe, A. Perry, I. Palma, J. Sageshima, R. Perez.
Department of Surgery, UC Davis Medical Center, Sacramento, CA
Studies have shown that Ex-Vivo Normothermic Perfusion (EVNP) has the potential to assess viability and function of high-risk deceased donor kidneys. A diuretic response to…
2017 American Transplant Congress
Costimulatory Blockade in Delayed Graft Function.
J. Von Visger,¹ A. Diez,¹ U. Nori,¹ T. Pesavento,¹ R. Pelletier,² A. Rajab,² A. El Hinnawi,² H. Winters.³
¹Medicine, The Ohio State University, Columbus, OH; ²Surgery, The Ohio State University, Columbus, OH; ³Pharmacy, The Ohio State University, Columbus, OH
Background: Delayed graft function (DGF) contributes to higher risk of rejection, poorer graft survival, hospital length of stay (LOS), and other morbidities. Studies also suggest…
2017 American Transplant Congress
The IL6/Th17 Pathway May Play Different Roles in Cell-Mediated and Antibody-Mediated Alloimmune Injury in Renal Allografts.
D. Dobi,¹ Q. Tang,² S. Chandran,³ F. Vincenti,³ Z. Laszik.¹
¹Department of Pathology, University of California, San Francisco, San Francisco, CA; ²Department of Surgery, Division of Transplant Surgery, University of California, San Francisco, San Francisco, CA; ³Department of Medicine, Division of Nephrology, University of California, San Francisco, San Francisco, CA
Purpose. IL6 has been shown to contribute to shifting the balance between tolerogenic regulatory T cells and proinflammatory Th17 cells towards the latter. Our study…
2017 American Transplant Congress
Long-Term Liver and Kidney Survival Following Combined Liver-Kidney Transplantation, with or without Preformed Donor-Specific Antibodies.
A. Del Bello,¹ O. Bestard,² J. Visentin,³ N. Congy-Jolivet,¹ L. Couzi,³ M. Neau-Cransac,³ F. Jambon,³ N. Kamar.¹
¹Nephrology and Organ Transplant Department, CHU Toulouse, Toulouse, France; ²Nephrology and Kidney Transplant Department, Bellvitge University Hospital, Barcelona, Spain; ³Nephrology and Kidney Transplant Department, CHU Bordeaux, Bordeaux, France
Introduction: Successful kidney transplantation despite a positive crossmatch is well known after combined liver-kidney transplantation (CLKT). However, recently, concerns regarding the impact of preformed anti-HLA…
2017 American Transplant Congress
Post-Donation GFR Changes in Living Kidney Donors.
E. Poggio,¹ S. Arrigain,² J. Augustine,¹ S. Flechner,³ J. Schold.²
¹Nephrology and Hypertension, Cleveland Clinic, Cleveland, OH; ²Qualitative Health Sciences, Cleveland Clinic, Cleveland, OH; ³Urology, Cleveland Clinic, Cleveland, OH
Living kidney donor transplantation is the preferred treatment for ESRD because it confers excellent outcomes for recipients and poses reasonable risks to donors. Post-donation glomerular…
2017 American Transplant Congress
Induction Therapy in Low Risk Elderly Kidney Transplant Recipients: Donor Factors.
F. Al Ammary, M. DeMarco, Q. Huang, E. King, S. Bay, A. Muzaale, A. Wiseman, D. Segev.
Johns Hopkins, Baltimore; University of Colorado, Denver
It is not known whether depleting induction is needed in low-risk elderly kidney transplant (KT) recipients in whom concern for infectious and complications is higher…
2017 American Transplant Congress
Protective Effects of Bryostatin-1 on Neutrophil Migration in an In Vitro Model of Ischemia Reperfusion Injury: Impact for Therapy.
F. Becker,¹ L. Kebschull,¹ T. Castor,³ D. Palmes,² S. Alexander,² F. Gavins.²
¹Department for General and Visceral Surgery, University Hospital Münster, Münster, Germany; ²Department of Molecular and Cellular Physiology, Department of Molecular and Cellular Physiology, Shreveport, LA; ³Aphios Corporation, Woburn, MA
Background: Ischemia-reperfusion injury (IRI) is an inherent component of solid organ transplantation and axiomatically linked to graft damage. In the kidney, IRI results in a…
2017 American Transplant Congress
Impact of Induction Immunosuppression on the Recurrence of Primary IgA Nephropathy.
K. Lee, C. Cho, N. Lee, K. Kim, S. Kim, J. Lee, J. Lee, H. Park, J. Park, S. Kim.
Department of Surgery, Samsung Medical Center, Seoul, Korea
PurposeIgA nephropathy (IgAN) may recur after kidney transplantation (KT) and potentially jeopardize the survival of the graft. The object of this study was to analyze…
2017 American Transplant Congress
Importance of HLA-DR Expression in Pediatric Renal Transplant Biopsies.
O. Moussa, S. Self, K. Twombley.
Medical University of South Carolina, Charleston
ObjectiveTo determine which types of injuries in pediatric kidney transplant patients were associated with HLA-DR expression.Design/MethodsA retrospective chart review was conducted of children receiving a…
2017 American Transplant Congress
Long-Term Outcome of Antibody-Mediated Rejection Due to Pre-Existing vs. De Novo DSA in Kidney Allograft Recipients.
O. Aubert,¹ C. Lefaucheur,¹ S. Higgins,¹ L. Hidalgo,² J. Duong Van Huyen,¹ D. Viglietti,¹ X. Jouven,¹ D. Glotz,¹ P. Halloran,² A. Loupy.¹
¹Paris Translational Research Center for Organ Transplantation, Paris, France; ²ATAGC, Edmonton, Canada
BackgroundAntibody-mediated rejection (ABMR) can occur in patients with pre-existing anti-HLA donor-specific antibodies (DSA) or in patients who develop de novo DSA. However, how these processes…