ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney"

  • 2018 American Transplant Congress

    Greater Access to Kidney Transplantation in Competitive DSAs: Due to Improved Referral?

    J. Adler,1 D. Chang,2 H. Yeh.2

    1Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI; 2Surgery, Massachusetts General Hospital, Boston, MA.

    INTRODUCTION: For patients with chronic kidney disease (CKD), access to kidney transplantation (ATT) varies across the 58 Donor Service Areas (DSAs) of the United States,…
  • 2018 American Transplant Congress

    De Novo Donor Specific Antibodies in Pediatric Kidney Transplant Recipients Are Highly Responsive to Therapy

    V. Sigurjonsdottir, P. Grimm.

    Pediatric Nephrology, Lucile Packard Children´s Hospital, Palo Alto, CA.

    Background: Pediatric Kidney transplant recipients who develop dnDSAs are at increased risk of allograft loss and rapid decline in GFR. C1q+ DSA, in particular, is…
  • 2018 American Transplant Congress

    Early Utilization of Telehealth in Kidney Transplantation

    T. Young, D. Hricik, E. Sanchez, N. Sarabu.

    Transplant Institute, University Hospitals of Cleveland, Cleveland, OH.

    Introduction: Telehealth is an emerging strategy to improve outcomes and decrease emergency department visits and readmissions. Utility of telehealth in kidney transplantation hasn't been much…
  • 2018 American Transplant Congress

    GDF15 Preventing Renal Ischemia Reperfusion Injury

    C. Zhu,1,2 A. Patel,1 Y. Su,1,2 J. Jiang,1 D. Lian,1 A. Sener,1 W. Min,1 P. Luke,1 D. Quan,1 K. Liu,2 X. Zheng.1

    1University of Western Ontario, London, ON, Canada; 2Jilin University, ChangChun, China.

    Rationale: Ischemia reperfusion (I/R) injury still remains one of main causes of early renal dysfunction in kidney transplantation. There are no effective treatments for preventing…
  • 2018 American Transplant Congress

    Risk of ESRD in Prior Living Kidney Donors

    J. Wainright, A. Robinson, A. Wilk, D. Klassen, W. Cherikh, D. Stewart.

    UNOS, Richmond, VA.

    We studied development of End Stage Renal Disease (ESRD) in living kidney donors (LKDs) who donated in the US between 1994 and 2016 (n=123,523), using…
  • 2018 American Transplant Congress

    Comparison of Microvascular Inflammation in Renal Allograft Tissue between ABO Incompatible and ABO Compatible Kidney Transplantation

    E. Ko,1,2 B. Choi,1,2 C. Park,1,2 Y. Kim,1,2 C. Yang,1,2 B. Chung.1,2

    1Transplant Research Center, College of Medicine, Seoul St.Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea; 2Division of Nephrology, Department of Internal Medicine, College of Medicine, Seoul St.Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea.

    Background: Microvascular inflammation (MVI) is considered as a pathological marker for antibody-mediated rejection (AMR) in the presence of donor-specific antibody (DSA). We aimed to investigate…
  • 2018 American Transplant Congress

    Mortality of Live Kidney Donors in the UK: 15 Year Comparative Cohort Study

    N. Krishnan,1 L. Mumford,3 G. Lipkin,4 S. Fletcher,1 I. Gupta,5 P. Gill,6 R. Ryan,7 N. Raymond.8

    1Renal Unit, University Hospitals Coventry & Warwickshire NHS Trust, Coventry, United Kingdom; 2Faculty of Health and Life Sciences, Coventry University, Coventry, United Kingdom; 3Statistics and Clinical Studies, Organ Donation and Transplant, National Health Services Blood and Transplant, Bristol, United Kingdom; 4Renal Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom; 5Renal Unit, Heartlands Hospital, Birmingham, United Kingdom; 6Unit of Academic Primary Care, University of Warwick, Coventry, United Kingdom; 7Primary Care, Primary Care, West Midlands, Birmingham, United Kingdom; 8Statistics, University Hospitals Coventry & Warwickshire NHS Trust, Coventry, United Kingdom.

    To investigate the all-cause mortality o LDs in comparison with healthy controls.Ethics approval was in place to accrue data from database. Protocol reviewed and passed…
  • 2018 American Transplant Congress

    Hard-To-Place Kidney Offers: Granular Examination of Donor Risk Factors for Discard

    R. Narvaez, J. Nie, K. Noyes, M. Leeman, L. Kayler.

    Dept of Surgery, University at Buffalo, Buffalo, NY; Dept of Epidemiology and Environmental Sciences, University at Buffalo, Buffalo, NY; Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY.

    Background: Deceased-donor kidney discard rates remain high. Understanding risk factors for discard is difficult since most analyses lack granularity and sufficient sample of high disease…
  • 2018 American Transplant Congress

    Histogenomics: Molecular Profiling of Kidney Biopsies Predict Delayed Graft Function

    P. Rao,1 D. Deo,1 B. Fyfe-Kirschner,2 R. Siderits.2

    1NJ Sharing Network, New Providence, NJ; 2Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ.

    IntroductionHistologic assessments of donor renal biopsies for percentage global glomerulosclerosis, interstitial fibrosis and arterial sclerosis can predict renal graft failure post-transplant.The morphologic evaluation of renal…
  • 2018 American Transplant Congress

    mTORC2 Deficiency in CD11c+ dendritic Cells Promotes Acute Kidney Injury

    H. Dai,1,2 A. Watson,1 D. Fantus,1 L. Peng,2 A. Thomson,1 N. Rogers.1

    1Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh; 2Department of Urological Organ Transplantation, The Second Xiangya Hospital of Central South University, Changsha, China.

    Introduction: The role of the mammalian/mechanistic target of rapamycin (mTOR) in the pathophysiology of renal ischemia-reperfusion injury (IRI) is poorly characterized; furthermore, the influence of…
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