2022 American Transplant Congress
Long Term Follow-Up of a Phase 2 Clinical Trial to Induce Tolerance in Living Donor Kidney Transplant Recipients
*Purpose: 37 subjects were transplanted in a phase 2 protocol based upon tolerogenic CD8+/TCR-facilitating cells (FCR001) to induce tolerance in recipients of living donor kidney…2022 American Transplant Congress
Donor-Derived Cell-Free DNA Across the Spectrum of Solid Organ Transplantation
1Baylor Scott & White Health, Temple, TX, 2CareDx, Inc, Brisbane, CA
*Purpose: Donor-derived cell-free DNA (dd-cfDNA) is a robust and clinically useful analyte initially validated for kidney allograft surveillance. Emerging data support the utility of dd-cfDNA…2022 American Transplant Congress
Duration of Brain Death Does Not Impact Short Term Outcomes in Kidney Transplantation
*Purpose: In animal models, brain death has been shown to induce renal injury, primarily due to ischemia, inflammation, and alterations in hemodynamics. However, donor management…2022 American Transplant Congress
Successful Implementation of a Rural Appalachian Kidney Transplant Program; One Year Outcomes
*Purpose: Kidney transplantation has become the optimal treatment for end stage renal disease (ESRD), allowing dialysis free survival. Despite widespread availability of transplant programs; rural…2022 American Transplant Congress
Single Nuclei RNA-Sequencing Identifies Distinct Immune Cell Profile in Kidney Allograft Fibrosis
*Purpose: A major obstacle after kidney transplantation (KT) is chronic allograft dysfunction characterized by interstitial fibrosis and tubular atrophy (IFTA). Despite extensive research, the cellular…2022 American Transplant Congress
A Novel Non-Invasive Urine Method for Assessment of Kidney Dysfunction
1Nephrosant, Brisbane, CA, 2NephroSant, San Francisco, CA
*Purpose: A recent cohort study of 10 869 living kidney donors from ImmPort highlighted that 14.7% have postdonation events unto 40 yrs later, relating to increased…2022 American Transplant Congress
Hold the Opioids Please: Long-Term Outcomes Following an Opioid Minimization Protocol in Kidney Transplantation
Medical University of South Carolina, Charleston, SC
*Purpose: Opioid use following kidney transplantation (KTX) is associated with an increased risk of graft loss and mortality. Opioid minimization strategies and protocols have demonstrated…2022 American Transplant Congress
Successful Transplantation of CPRA 95-100% HLA Incompatible (HLA I) KPD Candidates: A New Combined KPD Matching Strategy at a Single Centre
*Purpose: The six components of the new strategy are Universal flexible assignments of unacceptable antigens (UA); individualized deletion of carefully selected UA; inclusion of compatible…2022 American Transplant Congress
Four-Year Patient Survival After Simultaneous Pancreas-Kidney Transplantation According to Graft Status Using Kaplan-Meier Survival Method and Competing Risk Model
*Purpose: Aim of this study is to compare the patient survival submitted to SPKT according to the status of graft losses, kidney, pancreas, or both…2022 American Transplant Congress
The Effect of Including Race Adjustment in EGFR for Black Living Kidney Donors
UNOS United Network For Organ Sharing, Richmond, VA
*Purpose: Current discussions about the calculation of estimated glomerular filtration rate (eGFR) have spurred studies on Black patients’ access to kidney transplantation, but less research…
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