Articles tagged "Kidney"

2019 American Transplant Congress
Sub-Optimal Renal Recovery and Progressive Chronic Kidney Disease after Living Kidney Donation
Y. Kim¹, C. Jeong², H. Kim², J. Ha³, C. Ahn¹, Y. Kim¹, H. Lee¹
¹Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of, ²Department of Urology, Seoul National University Hospital, Seoul, Korea, Republic of, ³Department of Surgery, Seoul National University Hospital, Seoul, Korea, Republic of
*Purpose: Post-operative renal recovery after nephrectomy is a substantial problem to be addressed in living kidney donors. Herein, we explored factors associated with renal recovery…
2019 American Transplant Congress
miR-20a Inhibits Autophagy by Targeting AKT and BIM in Renal Reperfusion Injury
T. Lin, T. Song, Y. Jiang, J. Liu, Z. Wang, L. Li, Z. Huang, Y. Fan, X. Wang
Organ Transplantation Center, Urology Department, Urology Research Institute, WestChina Hospital, Sichuan University, Chengdu, China
*Purpose: Previously, we found up-regulation of miR-20a after kidney ischemia reperfusion (I/R) injury and may serves as a protector; however, its specific mechanism remains unclear.Autophagy…
2019 American Transplant Congress
Assessment of the Relationship between Inflammation and Glomerular Filtration Rate
J. B. Ramirez-Gonzalez¹, L. E. Morales-BuenRostro², J. Furuzawa-Carballeda³, L. Garcia-Covarrubias⁴, R. L. Pacheco-Domínguez⁵, R. Durazo-Arvizu⁶, J. Alberu³, E. N. Cuevas-Medina⁷, M. López-Cervantes⁵, R. A. Osorio-Juárez⁵
¹Faculty of Medicine, Public Health Department, Universidad Nacional Autónoma de México, Mexico, Mexico, ²Department of Nephrology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico, Mexico, ³Department of Transplantation, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico, Mexico, ⁴Department of Transplantation, Hospital General de México Doctor Eduardo Liceaga, Mexico, Mexico, ⁵Faculty of Medicine, Department of Public Health, Universidad Nacional Autónoma de México, Mexico, Mexico, ⁶Department of Public Health Sciences, Loyola University Chicago, Chicago, IL, ⁷Department of Cardiology, Instituto Nacional de Cardiología Ignacio Chávez, Mexico, Mexico
*Purpose: Since the inflammatory phenomena that occur after transplantation are decisive factors for developing renal rejection, we decided to study how the elevation of some…
2019 American Transplant Congress
Transfer of Healthy Mitochondria in Established Ischemic Injury Reduces Progression to Interstitial Fibrosis and Tubular Atrophy
A. Bajwa¹, V. Bontha¹, D. Maluf¹, J. Eason², V. Mas³
¹UTHSC, Memphis, TN, ²Director of Transplant Institute, Memphis, TN, ³Director of Transplant Research Institute, Memphis, TN
*Purpose: Ischemia induces altered bioenergetics with increased mitochondrial swelling and reactive oxygen species (ROS) and ultimately degradation of cellular function. Therapeutic interventions that target to…
2019 American Transplant Congress
Incidence of Viral Infections in Kidney Transplant Recipients with Alemtuzumab or Rabbit Antithymocyte Globulin Induction
A. Brueckner¹, C. Truong¹, E. Yanqui¹, R. Baliga², L. Bowman¹
¹Tampa General Hospital, Tampa, FL, ²Florida Kidney Physicians, Tampa, FL
*Purpose: Monoclonal antibody therapy causes profound and sustained lymphocyte depletion thus increasing the risk of viral infections. While studies exist evaluating the outcomes of alemtuzumab…
2019 American Transplant Congress
Does Proton Pump Inhibitor Use Affect Renal Function in Kidney Transplant Recipients?
K. Schütte-Nütgen¹, D. J. Flothow¹, B. Suwelack¹, R. Schmidt², H. Pavenstädt¹, S. Reuter¹
¹Department of Internal Medicine D, University Hospital Münster, Münster, Germany, ²Institute of Biostatistics and Clinical Research, University Hospital Münster, Münster, Germany
*Purpose: Recently, proton pump inhibitor (PPI) intake has been linked to acute kidney injury and chronic kidney disease. In the setting of renal transplantation, it…
2019 American Transplant Congress
Is Narrative Storytelling Ethical to Use to Educate the Public about Living Donation? Transplant Professionals Weigh In
W. Balliet¹, L. Holland-Carter¹, S. N. Maurer¹, M. P. Salas¹, C. S. Anderson², O. N. Ranasinghe², A. D. Waterman²
¹Division of Bio-behavioral Medicine, Medical University of South Carolina, Charleston, SC, ²Division of Nephrology, UCLA School of Medicine, Los Angeles, CA
*Purpose: Recent studies suggest that integrating health information through narrative stories can improve understanding of complex health conditions in diverse populations, especially those with low…
2019 American Transplant Congress
Are Protocol Biopsies Necessary for Pediatric Renal Transplant Recipients?
E. Allred, E. Ingulli
Pediatrics, UCSD, San Diego, CA
*Purpose: Renal allograft survival indirectly correlates with acute rejection episodes. Subacute rejection is also associated with decreased graft survival. Protocol biopsies (bxs) have been implemented…
2019 American Transplant Congress
Variations in Recipient and Donor Clinical Characteristics between Kidney Transplant Centers
W. T. McKinney¹, M. Bruin², S. Chu², D. Schladt³, J. Snyder³, A. Matas⁴, B. Kasiske⁵, A. K. Israni³
¹Nephrology, Hennepin Healthcare Research Institute, Minneapolis, MN, ²College of Design, University of Minnesota, St. Paul, MN, ³Scientific Registry of Transplant Recipients, Hennepin Healthcare Research Institute, Minneapolis, MN, ⁴Department of Surgery, University of Minnesota, Minneapolis, MN, ⁵Department of Medicine, Hennepin Healthcare, Minneapolis, MN
*Purpose: When a patient can choose at which kidney transplant program to establish care, prior knowledge of program acceptance practices (of candidates and donors) can…
2019 American Transplant Congress
Differences in the Cost of Kidney Organ Recovery by Organ Procurement Organization Size
P. J. Held¹, J. Bragg-Gresham², J. P. Roberts³
¹Stanford University, Stanford, CA, ²Univ of Michigan, Michigan, MI, ³Univ of California-San Francisco, San Francisco, CA
*Purpose: Economic theory suggests that there should be an initial decrease in costs of products as production levels increase. Using data from independent OPOs we…