Articles tagged "Kidney"

2019 American Transplant Congress
Aquaporins May Be Involved in Renal Ischemia-Reperfusion Injury by Affecting the Pyroptosis of Renal Tubular Epithelial Cells
T. Lin, Y. Fan, Y. Jiang, J. Liu, Z. Wang, L. Li, T. Song, Z. Huang, X. Wang
Organ Transplantation Center, Urology Department, Urology Research Institute, WestChina Hospital, Sichuan University, Chengdu, China
*Purpose: To determine whether aquaporins (AQPs) are involved in renal ischemia-reperfusion injury (IRI) by affecting the pyroptosis of renal tubular epithelial cells.*Methods: Hypoxia reoxygenation (H/R)…
2019 American Transplant Congress
Urinary Biomarkers of Kidney Injury in Liver Transplant Recipients with Calcineurin Inhibitors Based Immunosuppression
D. Maluf¹, V. Bontha¹, A. Bajwa², A. Abdelaal¹, C. Koo¹, J. D. Eason², V. Mas²
¹UTHSC, Memphis, TN, ²Transplant Institute, Memphis, TN
*Purpose: Renal dysfunction post solid organ transplantation is common and associated with several risk factors. Messenger RNA encoding for genes expressed along the nephron and…
2019 American Transplant Congress
Can Financial Incentives Improve Patient Compliance with Optn Live Kidney Donor Follow-Up Policy? Results of a Randomized Controlled Trial
M. Henderson, M. Waldram, S. DiBrito, A. Thomas, F. Al Ammary, S. Ottman, A. Massie, J. Garonzik Wang, D. Segev
Johns Hopkins, Baltimore, MD
*Purpose: The Organ Procurement and Transplantation Network (OPTN) requires transplant hospitals to monitor live kidney donors (LKDs) for 2 years post-donation. However, the majority (57%)…
2019 American Transplant Congress
Surgical Outcome and Analysis of Risk of Complications in Kidney Donors Receiving Laparoscopic Live Donor Nephrectomy
C. Yang, C. Yeh, C. Lee, C. Chen, I. Lai, P. Lee, M. Tsai
Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan
*Purpose: Laparoscopic live donor nephrectomy has adopted for more than 20 years. But the operative procedure is still technically demanding, and allows almost no margin…
2019 American Transplant Congress
Regeneration of Kidney with a Novel Biomimetic Vascular Scaffold
S. Min¹, H. Mo¹, A. Han¹, J. Ha¹, J. Yoo²
¹Seoul National University Hospital, Seoul 110-744, Korea, Republic of, ²Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC
*Purpose: Appropriate vascularization is one of the most important issues to be addressed in the clinical application of 3D bioengineered organ.*Methods: We have fabricated biomimetic…
2019 American Transplant Congress
When to Hold: Apixaban in Renal Transplant Recipients
V. H. Do¹, D. Haakinson², K. D. Belfield¹
¹Yale New Haven Hospital, New Haven, CT, ²Yale School of Medicine, New Haven, CT
*Purpose: Renal transplant recipients (RTRs) may develop deep venous thrombosis (DVT), pulmonary embolism (PE), or atrial fibrillation requiring treatment with oral anticoagulation. There is limited…
2019 American Transplant Congress
Performance Improvement Initiative: Ambulatory Tool to Improve Tacrolimus Intrapatient Variability (IPV) Monitoring in Kidney & Liver Transplant Recipients
T. E. Kaiser¹, N. S. Ejaz¹, S. Tremblay¹, N. J. Parrish², S. Schinasi², J. Harris², A. Govil¹, N. Anwar¹, R. R. Alloway¹
¹University of Cincinnati, Cincinnati, OH, ²UC Health, Cincinnati, OH
*Purpose: High tacrolimus (TAC) intrapatient variability (IPV) is associated with poorer outcomes. Manual monitoring of TAC IPV is labor intensive and not always feasible. As…
2019 American Transplant Congress
Utilization of Hepatitis C Donors is Safe and Cost Effective
J. Shaw, D. Reino, N. Kapila, K. Al Khalloufi, S. Ebaid, S. Rhazouani, X. Zervos, J. Vanatta, N. Agrawal
Cleveland Clinic, Weston, FL
*Purpose: The use of hepatitis C (hep C) positive donors has become increasingly attractive with the advent of improved curative pharmacologic treatments. As a result…
2019 American Transplant Congress
Discovery and Validation of an Early Post-Transplant Biomarker Model Predictive of Chronic Kidney Disease in Liver Transplant Recipients
J. Levitsky¹, S. Asrani², G. Klintmalm², T. Schiano², A. Moss³, K. Chavin⁴, C. Miller⁵, L. Zhao⁶, K. Guo⁶, N. Bridges⁷, J. Odim⁷, M. Brown⁷, D. Ikle⁸, B. Armstrong⁸, M. Abecassis⁹
¹Gastroenterology and Hepatology, Northwestern University, Chicago, IL, ²Baylor, Dallas, TX, ³Mayo Arizona, Phoenix, AZ, ⁴Case Western, Cleveland, OH, ⁵Cleveland Clinic, Cleveland, OH, ⁶Northwestern University, Chicago, IL, ⁷NIAID, Bethesda, MD, ⁸Rho, Chapel Hill, NC, ⁹Comprehensive Transplant Center, Northwestern University, Chicago, IL
*Purpose: A significant proportion of patients develop chronic kidney disease after liver transplantation (LT). We aimed to develop clinical/protein models to predict future GFR deterioration…
2019 American Transplant Congress
The Immigrant Bonus: Non US Deceased Donor Kidney Transplant Recipients Have Superior Outcomes versus US Citizen Recipients. A Retrospective Study of 30,092 Subjects Using the Organ Procurement and Transplant Network (OPTN) from 1992-2015
T. Butler¹, A. Rana², S. Fink¹
¹Transplant Surgery, Crozer Prospect Medical Center-Drexel University, Upland, PA, ²Transplant Surgery, Baylor College of Medicine, Houston, TX
*Purpose: In 2017, there were 19,849 kidney transplant recipients, and most of these patients were US Citizens1. There has been however, a significant amount non-US…