Articles tagged "Kidney"

2019 American Transplant Congress
Incidence of De Novo Donor Specific Antibodies and Treatment Response for AMR in Pediatric Kidney Transplant Recipients
S. Gattis¹, R. Liverman¹, A. Serluco¹, J. Yin¹, H. C. Sullivan², R. A. Bray³, H. M. Gebel³, S. Jernigan⁴, R. George⁴, P. D. Winterberg⁴, R. Garro⁴
¹Children's Healthcare of Atlanta, Atlanta, GA, ²Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, ³Emory University Hospital, Atlanta, GA, ⁴Department of Pediatrics, Emory University School of Medicine, Atlanta, GA
*Purpose: Antibody-mediated rejection (AMR) is a significant complication in renal transplant patients. The aim of this study was to evaluate the incidence of de novo…
2019 American Transplant Congress
Vimentin Inhibition Improves Post-Transplant Survival in a Mouse Renal Transplant Model
R. Lopez-Soler¹, Z. Zhang², H. Chin³, J. Wang⁴, K. Ridge⁵
¹Albany Medical College, Albany, NY, ²Microsurgery Core, Comprehensive Transplant Center, Northwestern University, Feinberg School of Medicine, Chicago, IL, ³Molecular and Cellular Physiology, Albany Medical College, Albany, NY, ⁴Microsurgery Core, Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁵Northwestern Univesity, Feinberg School of Medicine, Chicago, IL
*Purpose: Most renal transplants ultimately fail secondary to chronic allograft nephropathy (CAN). The development of Epithelial to Mesenchymal Transition (EMT) in renal tubular epithelial cells…
2019 American Transplant Congress
Room for Optimism; Improvement in Long-Term Patient and Graft Survival of Kidney Transplants in the United States over the past Three Decades
C. Wu, A. Rana, N. Galvan, C. O'Mahony, J. Goss, B. Murthy
Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX
*Purpose: Previous studies indicated that the short-term (1 year) allograft survival of kidney transplants has improved significantly over the years. However, less is known about…
2019 American Transplant Congress
Dialysis Facility Profit Status and Referral for Kidney Transplantation
E. R. Walker¹, L. J. McPherson¹, J. C. Gander², S. Pastan¹, R. E. Patzer¹
¹Emory University School of Medicine, Atlanta, GA, ²Kaiser Permanente Georgia, Atlanta, GA
*Purpose: Patients receiving dialysis treatment in for-profit dialysis facilities have historically lower rates of kidney transplantation (KT) compared to non-profit facilities, but the impact of…
2019 American Transplant Congress
Earlier Transplant Education as CKD Progresses? CKD 3-5 Patients and Providers Weigh In
A. D. Waterman¹, O. N. Ranasinghe¹, A. F. Lipsey², C. S. Anderson¹, A. Alem³, C. Bozzolo⁴, B. Dub³, S. L. Henry³, B. Mittman³
¹Division of Nephrology, UCLA School of Medicine, Los Angeles, CA, ²Terasaki Research Institute, Los Angeles, CA, ³Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, CA, ⁴Insight Policy Research, Arlington, VA
*Purpose: To increase preemptive and early transplant rates, transplant education must be delivered along the entire chronic kidney disease (CKD) spectrum. To understand patients’ education…
2019 American Transplant Congress
Hepatitis C Positive Donor to Negative Recipient Kidney Transplantation: A Single Center Real World Experience
N. Jandovitz, V. Nair, E. Grodstein, E. Molmenti, A. Fahmy, M. Bhaskaran, L. Teperman
North Shore University Hospital, Manhasset, NY
*Purpose: Several small studies have shown that transplanting a hepatitis C virus (HCV) negative recipient with a HCV positive donor is feasible in a research…
2019 American Transplant Congress
Recombinant Apoptosis Inhibitor of Macrophage Protein Ameliorates Transplant Ischemia-Reperfusion Injury
J. Y. Lee¹, X. Zhang², D. Lian³, A. R. Haig⁴, T. Miyazaki⁵, L. Gunaratnam⁶
¹Department of Microbiology and Immunology, Western University, London, ON, Canada, ²Matthew Mailing Centre for Translational Transplant Studies, London Health Sciences Centre, London, ON, Canada, ³Matthew Mailing Centre for Translational Transplant Studies, London Health Sciences Centre, Lodnon, ON, Canada, ⁴Department of Pathology, Western University, London, ON, Canada, ⁵Center for Disease Biology and Integrative Medicine, University of Tokyo, Tokyo, Japan, ⁶Department of Medicine, Western University, London, ON, Canada
*Purpose: Ischemia-reperfusion injury (IRI) during kidney transplantation is associated with acute rejection and long-term graft loss. During IRI, pro-inflammatory mediators (e.g. HMGB1) released from necrotic…
2019 American Transplant Congress
Evaluation of Pneumocystis jirovecii Pneumonia Prophylaxis among Kidney and Liver Transplant Recipients; Trimethoprim/Sulfamethoxazole vs Alternative Therapies
E. Aldag, C. Pagels, R. Pedersen, I. Nadeem, V. Gunabushanam, A. Sahajpal, T. J. Dilworth
Aurora St Luke's Medical Center, Milwaukee, WI
*Purpose: To describe Pneumocystis Jirovecii Pneumonia (PJP) prophylaxis (ppx) practices in our transplant recipients and to determine its safety and efficacy.*Methods: Retrospective review of kidney…
2019 American Transplant Congress
Alemtuzumab versus Anti-Thymocyte Globulin Induction in the Setting of Immediate Post-Renal Transplant Acute Tubular Necrosis in an Urban, Minority Patient Population
K. Tejani, E. Benedetti, A. Lichvar
University of Illinois at Chicago, Chicago, IL
*Purpose: Post-renal transplant (RTx) delayed graft function (DGF) or slow graft function (SGF) increase the risk of rejection and impair allograft function. Lymphocyte depleting induction…
2019 American Transplant Congress
How Challenging Will Be My Living Donor? CT Scan and Clinical Evaluation Can Predict Technical Difficulty of Laparoscopic Donor Nephrectomy
V. Bianchi¹, G. Spagnoletti¹, R. Iezzi², F. E. Rossini¹, A. Posa², A. E. Rossini¹, M. P. Salerno¹, F. Citterio¹, J. Romagnoli¹
¹Renal Transplant Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy, ²Radiology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy
*Purpose: There are no objective parameters for predicting the difficulty of laparoscopic donor nephrectomy (LDN). Our aim was to identify the correlation between demographic and…