Articles tagged "Kidney"

2019 American Transplant Congress
Developing a Patient Specific Search: Feedback from Kidney Transplant Candidates and Recipients
W. T. McKinney¹, M. J. Bruin², C. R. Schaffhausen¹, S. Chu², J. Snyder³, A. Matas⁴, B. Kasiske⁵, A. K. Israni¹
¹Nephrology, Hennepin Healthcare Research Institute, Minneapolis, MN, ²College of Design, University of Minnesota, St. Paul, MN, ³Scientific Registry of Transplant Recipients, Hennepin Healthcare Research Institute, Minneapolis, MN, ⁴Department of Surgery, University of Minnesota, Minneapolis, MN, ⁵Department of Medicine, Hennepin Healthcare, Minneapolis, MN
*Purpose: Patients in need of kidney transplantation face numerous obstacles when identifying a transplant center for treatment. Acceptance criteria, waiting time, and post-transplant allograft survival…
2019 American Transplant Congress
Costs of Kidney Recoveries Varies Dramatically across Organ Procurement Organizations
J. P. Roberts¹, J. Bragg-Gresham², P. J. Held³
¹Univ of California-San Francisco, San Francisco, CA, ²University of Michigan, Ann Arbor, MI, ³Stanford, Stanford, CA
*Purpose: Report on the wide variation across OPOs in the cost of kidney recovery from deceased donors.*Methods: Cost reports (CMS 216-94 Form) from 52 Independent…
2019 American Transplant Congress
Outcomes in Non-A1 and Non A1 B to B Deceased Donor Renal Transplantation Are Comparable to B Donor Renal Transplants
A. Brar, L. Kwon, A. Gruessner, F. Tedla, R. Gruessner, N. Sumrani, D. John, J. Renz, M. O. Salifu
SUNY Downstate Medical Center, Brooklyn, NY
*Purpose: Blood type B patients wait longer to get deceased donor (DD) renal transplants compared to other blood types. On December 2014, the US national…
2019 American Transplant Congress
Mitochondrial Dysfunction and Metabolic Reprogramming: Critical Features of Cyclosporine A Nephrotoxicity
A. A. Zmijewska, G. Benavides, V. Darley-Usmar, J. W. Zmijewski, R. B. Mannon
University of Alabama at Birmingham, Birmingham, AL
*Purpose: Calcineurin inhibitors (CNIs) are potent immunosuppressants but over time contribute to allograft fibrosis. Clinical efforts to minimize or avoid CNI have not been uniformly…
2019 American Transplant Congress
Sub-Optimal Renal Recovery and Progressive Chronic Kidney Disease after Living Kidney Donation
Y. Kim¹, C. Jeong², H. Kim², J. Ha³, C. Ahn¹, Y. Kim¹, H. Lee¹
¹Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of, ²Department of Urology, Seoul National University Hospital, Seoul, Korea, Republic of, ³Department of Surgery, Seoul National University Hospital, Seoul, Korea, Republic of
*Purpose: Post-operative renal recovery after nephrectomy is a substantial problem to be addressed in living kidney donors. Herein, we explored factors associated with renal recovery…
2019 American Transplant Congress
miR-20a Inhibits Autophagy by Targeting AKT and BIM in Renal Reperfusion Injury
T. Lin, T. Song, Y. Jiang, J. Liu, Z. Wang, L. Li, Z. Huang, Y. Fan, X. Wang
Organ Transplantation Center, Urology Department, Urology Research Institute, WestChina Hospital, Sichuan University, Chengdu, China
*Purpose: Previously, we found up-regulation of miR-20a after kidney ischemia reperfusion (I/R) injury and may serves as a protector; however, its specific mechanism remains unclear.Autophagy…
2019 American Transplant Congress
Assessment of the Relationship between Inflammation and Glomerular Filtration Rate
J. B. Ramirez-Gonzalez¹, L. E. Morales-BuenRostro², J. Furuzawa-Carballeda³, L. Garcia-Covarrubias⁴, R. L. Pacheco-Domínguez⁵, R. Durazo-Arvizu⁶, J. Alberu³, E. N. Cuevas-Medina⁷, M. López-Cervantes⁵, R. A. Osorio-Juárez⁵
¹Faculty of Medicine, Public Health Department, Universidad Nacional Autónoma de México, Mexico, Mexico, ²Department of Nephrology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico, Mexico, ³Department of Transplantation, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico, Mexico, ⁴Department of Transplantation, Hospital General de México Doctor Eduardo Liceaga, Mexico, Mexico, ⁵Faculty of Medicine, Department of Public Health, Universidad Nacional Autónoma de México, Mexico, Mexico, ⁶Department of Public Health Sciences, Loyola University Chicago, Chicago, IL, ⁷Department of Cardiology, Instituto Nacional de Cardiología Ignacio Chávez, Mexico, Mexico
*Purpose: Since the inflammatory phenomena that occur after transplantation are decisive factors for developing renal rejection, we decided to study how the elevation of some…
2019 American Transplant Congress
Transfer of Healthy Mitochondria in Established Ischemic Injury Reduces Progression to Interstitial Fibrosis and Tubular Atrophy
A. Bajwa¹, V. Bontha¹, D. Maluf¹, J. Eason², V. Mas³
¹UTHSC, Memphis, TN, ²Director of Transplant Institute, Memphis, TN, ³Director of Transplant Research Institute, Memphis, TN
*Purpose: Ischemia induces altered bioenergetics with increased mitochondrial swelling and reactive oxygen species (ROS) and ultimately degradation of cellular function. Therapeutic interventions that target to…
2019 American Transplant Congress
Incidence of Viral Infections in Kidney Transplant Recipients with Alemtuzumab or Rabbit Antithymocyte Globulin Induction
A. Brueckner¹, C. Truong¹, E. Yanqui¹, R. Baliga², L. Bowman¹
¹Tampa General Hospital, Tampa, FL, ²Florida Kidney Physicians, Tampa, FL
*Purpose: Monoclonal antibody therapy causes profound and sustained lymphocyte depletion thus increasing the risk of viral infections. While studies exist evaluating the outcomes of alemtuzumab…
2019 American Transplant Congress
Does Proton Pump Inhibitor Use Affect Renal Function in Kidney Transplant Recipients?
K. Schütte-Nütgen¹, D. J. Flothow¹, B. Suwelack¹, R. Schmidt², H. Pavenstädt¹, S. Reuter¹
¹Department of Internal Medicine D, University Hospital Münster, Münster, Germany, ²Institute of Biostatistics and Clinical Research, University Hospital Münster, Münster, Germany
*Purpose: Recently, proton pump inhibitor (PPI) intake has been linked to acute kidney injury and chronic kidney disease. In the setting of renal transplantation, it…