2019 American Transplant Congress
Eculizumab Deposition in Renal Transplants
*Purpose: Eculizumab is a recombinant humanized IgG monoclonal antibody that inhibits C5, thereby preventing the activation of C5a and formation of membrane attack complex C5b-C9.…2019 American Transplant Congress
Extremes of Body Mass Index is Associated with Inferior Renal Allograft Outcomes in Type 2 Diabetic Deceased Donor Renal Transplant Recipients
SUNY Downstate Medical Center, Brooklyn, NY
*Purpose: We evaluated the trends and renal allograft outcomes in type 2 diabetic renal transplant recipients stratified by body mass index (BMI).*Methods: All adult type…2019 American Transplant Congress
Transplant Nephrologist
*Purpose: Matching rates of very highly sensitized patients with cPRA of 91 - 100% (VHSP) and blood type O recipients of ABO incompatible donors (ABO…2019 American Transplant Congress
Multiplexed Droplet Single-Cell RNA-Sequencing for Cellular Profiling of Transplant Rejection
Department of Surgery, UCSF, San Francisco, CA
*Purpose: Multiplexed droplet single-cell RNA-sequencing (mdscRNA-seq) has been utilized across many tissue types for fast and paralleled transcriptomic profiling. However, maintaining sample identity for differential…2019 American Transplant Congress
Donor-Recipient Matching in Kidney Transplant: The Whole is Greater Than the Sum of the Parts
Dalhousie University, Halifax, NS, Canada
*Purpose: In deceased donor kidney transplantation, strategic organ allocation is expected to prolong patient and graft survival after transplant. The aim of this study was…2019 American Transplant Congress
Can National Data Predict Which Older Kidney Donors Are More Likely to Yield Higher eGFR 1-Year Post-Transplant?
1United Network for Organ Sharing, Richmond, VA, 2University of Minnesota, Minneapolis, MN
*Purpose: Older donors (65+) have been utilized at low rates despite accounting for the majority of deaths in the U.S. (73%, CDC). Kasiske et al.…2019 American Transplant Congress
Variation in Living Donor Kidney Transplantation and the Impact of Medicaid Expansion
*Purpose: Living donor kidney transplant (LDKTx) is the preferred treatment for end-stage renal disease (ESRD). Medicaid Expansion increased insurance coverage and this influx of insured…2019 American Transplant Congress
Clinical Outcomes and Risk Factors for Delayed or Slow Graft Function in an Adult, Urban Renal Transplant Population
University of Illinois at Chicago, Chicago, IL
*Purpose: Delayed graft function (DGF) and slow graft function (SGF) are shown to be associated with higher risk of rejection and suboptimal allograft function over…2019 American Transplant Congress
Sex Specific Regulation of Podocyte-Specific Genes and Proteins Determines Glomerular Response to mTOR Inhibition
*Purpose: mTOR inhibitors are increasingly used in transplantation with high interindividual variation in proteinuric responses. Although males have higher prevalence and faster progression of glomerular…2019 American Transplant Congress
Evaluation Of BK Polyomavirus Monitoring And Management In Kidney Transplant Recipients
Henry Ford Hospital, Detroit, MI
*Purpose: BK polyomavirus (BKV) is an opportunistic infection that can lead to BKV nephropathy and premature graft loss within the first year post-transplant. The mainstay…
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