ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney"

  • 2020 American Transplant Congress

    Utility of Bimonthly Viral Monitoring for Late-Onset Cytomegalovirus Infections in Kidney Transplant Recipients

    I. Melgarejo1, D. Jorgensen2, S. Hariharan2, C. Puttarajappa2

    1Department of Medicine, Renal-Electrolyte Division, University of Pittsburgh, Pittsburgh, PA, 2Department of Surgery, Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA

    *Purpose: Kidney transplant recipients with high-risk cytomegalovirus (CMV) serostatus are at risk for late onset CMV after cessation of antiviral prophylaxis.1-2 Evidence for post-prophylactic viral…
  • 2020 American Transplant Congress

    Cyclo(His-Pro) Prevents Against Renal Injury Through Activating Nrf2-Mediated Pathway

    J. Moon1, Y. Kim1, H. Jung2, J. Kim1, W. Ju3, H. Lee1, J. Lee4, C. Lee5, D. Kim1, Y. Kim1, S. Yang6

    1Seoul National University Hospital, Seoul, Korea, Republic of, 2R&D Center, NovMetaPharma Co., Ltd, Pohang, Gyeongbuk, Korea, Republic of, 3Seoul National University Biomedical Research Institute, Seoul, Korea, Republic of, 4Nephrology Clinic, National Cancer Center, Goyang, Korea, Republic of, 5Cheju Halla General Hospital, Jeju-do, Korea, Republic of, 6Kidney Research Institute, Seoul National University College of Medicine, Seoul, Korea, Republic of

    *Purpose: Cyclic(His-Pro) (CHP) is an endogenous cyclic dipeptide that has antioxidative, anti-inflammatory effect via Nuclear factor erythroid 2-related factor (Nrf2) pathway. Endogenous CHP is distributed…
  • 2020 American Transplant Congress

    Four Years of KAS: A Pediatric Specific Report

    J. Foutz1, J. Smith2, A. Wilk1, K. Vakili3, G. Mazariegos4, S. Bartosh5

    1United Network for Organ Sharing, Richmond, VA, 2Seattle Children's Hospital, Seattle, WA, 3Boston Children's Hospital, Boston, MA, 4Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, 5University of Wisconsin Hospital and Clinics, Madison, WI

    *Purpose: On 12/4/14, the Organ Procurement and Transplantation Network (OPTN) implemented a new Kidney Allocation System (KAS). To maintain pediatric priority, KAS gave pediatric candidates…
  • 2020 American Transplant Congress

    Severity of Donor Acute Kidney Injury Does Not Impact Long-Term Outcomes in Deceased Donor Renal Transplant Recipients

    A. Brar1, A. Gruessner2, D. Adey1, M. Salifu2

    1University of California, San Francisco, San Francisco, CA, 2SUNY Downstate Medical Center, Brooklyn, NY

    *Purpose: Kidneys with increased donor terminal creatinine are frequently discarded. This study used national data to assess renal allograft and patient outcomes in deceased donor…
  • 2020 American Transplant Congress

    Intraoperative Oxygen Delivery and Acute Kidney Injury after Liver Transplantation

    W. Kim, H. Lee, H. Yoon, K. Suh

    Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Korea, Republic of

    *Purpose: Although intraoperative hemodynamic variables were reported to be associated with acute kidney injury (AKI) after liver transplantation, the time-dependent association between intraoperative oxygen delivery…
  • 2020 American Transplant Congress

    Introduction of Preemptive Pharmacogenomic Testing in Kidney Transplant Recipients: Early Evaluation of the Clinical Impact of Genomic Guided Tacrolimus Dosing

    G. Girone1, V. Do1, K. Belfield1, R. Pulk1, E. Cohen1, E. Marin2

    1Department of Pharmacy, Yale New Haven Hospital, New Haven, CT, 2Department of Nephrology, Yale School of Medicine, New Haven, CT

    *Purpose: Tacrolimus is widely accepted as the mainstay of immunosuppression in solid organ transplant. Inherited differences in CYP3A activity are known to contribute to dosing…
  • 2020 American Transplant Congress

    Associations of Chronic Kidney Disease with Temperature, Ancestry and Employment

    A. A. Connor, B. I. Shaw, K. V. Ravindra

    Surgery, Duke University, Durham, NC

    *Purpose: We sought to assess the suggested associations of chronic kidney disease (CKD) of unknown origin, also known as Mesoamerican Nephropathy, with temperature, ancestry and…
  • 2020 American Transplant Congress

    Hemodialysis (HD) Treatment Associates with Increased Risk of Delayed Graft Function (DGF) after Renal Transplantation (RT) and Augmented Cd4 and Cd8 T Cell Proliferation Compared to Peritoneal Dialysis (PD)

    A. Angeletti1, C. Donadei1, G. Donati1, G. Di Certo1, D. Conte1, L. Gasperoni1, E. Pelizzaro1, C. Guglielmo1, G. Comai1, P. Cravedi2, G. La Manna1

    1DIMES, S.Orsola-Malpighi Hospital, Bologna University, Bologna, Italy, 2DIMES, Icahn School of Medicine at Mount Sinai, New York, NY, US, New York, NY

    *Purpose: Delayed graft function (DGF) is a common event after RT that increases the risk of acute rejection and early graft loss. The impact of…
  • 2019 American Transplant Congress

    Did COIIN Cohort A Maintain Graft Survival Performance While Increasing Moderate to High KDPI Transplants?

    J. Foutz, R. J. Carrico, K. Sisaithong, H. Tosoc-Haskell, D. Klassen

    Research, United Network for Organ Sharing, Richmond, VA

    *Purpose: The Collaborative Innovation and Improvement Network (COIIN) was a 3-year OPTN project aimed at increasing the utilization of kidneys with a kidney donor profile…
  • 2019 American Transplant Congress

    The Role of CD47/SIRPα and CD47/TSP-1 Pathways in Pig-to-Baboon Kidney Transplantation Using hCD47 Transgenic Kidneys

    K. Takeuchi1, Y. Ariyoshi1, T. Pomposelli1, L. Boyd1, D. Ekanayake-Alper1, S. Arn1, R. Hawley1, D. Ayares2, M. Lorber3, M. Sykes1, D. Sachs1, R. Johnson4, K. Yamada1

    1CCTI/Surgery, Columbia University Medical Center, New York, NY, 2Revivicor Inc., Blacksburg, VA, 3Lung BioTechnology PBC, Silver Spring, MD, 4Division of Renal Diseases and Hypertension, University of Colorado, Aurora, CO

    *Purpose: We have recently reported that both CD80 upregulation and the degradation of SMPDL-3b on glomerular podocytes are involved in the development of post kidney…
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