2020 American Transplant Congress
Four Years of KAS: A Pediatric Specific Report
*Purpose: On 12/4/14, the Organ Procurement and Transplantation Network (OPTN) implemented a new Kidney Allocation System (KAS). To maintain pediatric priority, KAS gave pediatric candidates…2020 American Transplant Congress
Severity of Donor Acute Kidney Injury Does Not Impact Long-Term Outcomes in Deceased Donor Renal Transplant Recipients
*Purpose: Kidneys with increased donor terminal creatinine are frequently discarded. This study used national data to assess renal allograft and patient outcomes in deceased donor…2020 American Transplant Congress
Intraoperative Oxygen Delivery and Acute Kidney Injury after Liver Transplantation
Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Korea, Republic of
*Purpose: Although intraoperative hemodynamic variables were reported to be associated with acute kidney injury (AKI) after liver transplantation, the time-dependent association between intraoperative oxygen delivery…2020 American Transplant Congress
Introduction of Preemptive Pharmacogenomic Testing in Kidney Transplant Recipients: Early Evaluation of the Clinical Impact of Genomic Guided Tacrolimus Dosing
*Purpose: Tacrolimus is widely accepted as the mainstay of immunosuppression in solid organ transplant. Inherited differences in CYP3A activity are known to contribute to dosing…2020 American Transplant Congress
Associations of Chronic Kidney Disease with Temperature, Ancestry and Employment
Surgery, Duke University, Durham, NC
*Purpose: We sought to assess the suggested associations of chronic kidney disease (CKD) of unknown origin, also known as Mesoamerican Nephropathy, with temperature, ancestry and…2020 American Transplant Congress
Hemodialysis (HD) Treatment Associates with Increased Risk of Delayed Graft Function (DGF) after Renal Transplantation (RT) and Augmented Cd4 and Cd8 T Cell Proliferation Compared to Peritoneal Dialysis (PD)
*Purpose: Delayed graft function (DGF) is a common event after RT that increases the risk of acute rejection and early graft loss. The impact of…2020 American Transplant Congress
Activated CD27+CD21– Subset Dominate the Memory B Cell Response During Antibody-Mediated Rejection of Kidney Allografts
1Surgery, University of Pittsburgh, Pittsburgh, PA, 2Inserm UMR 976, Paris, France
*Purpose: The role of alloreactive memory B (mB) cells in the pathogenesis of antibody-mediated rejection (ABMR) is increasingly recognized. Yet, a comprehensive characterization of mB…2020 American Transplant Congress
Angiotensin II Type 1 Receptor Antibodies are Associated with Younger Age and Renal Dysfunction in Pediatric Kidney Transplantation
1UCLA, Los Angeles, CA, 2Duke, Durham, NC, 3Emory, Atlanta, GA, 4Stanford, Stanford, CA
*Purpose: The significance of non-HLA antibodies in renal transplantation remains unclear. In small single center retrospective studies, angiotensin II type 1 receptor antibody (AT1R-Ab) has…2020 American Transplant Congress
Single Cell Analysis of Living Donor Kidneys Characterizes Resident Parenchymal and Immune Populations in Male and Female Donors
*Purpose:Understanding the molecular profiles and individual contributions of kidney parenchymal and resident/infiltrating immune cells during homeostasis would facilitate development of treatments for kidney graft disease.…2020 American Transplant Congress
Incidence of Antibody Mediated Rejection in Living Kidney Transplant Recipients with Sensitizing History
*Purpose: A donor-reactive alloimmune memory response can arise from prior exposure to foreign human leukocyte antigen by sensitization history in transplant recipients. Assessing risk levels…
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