Articles tagged "Kidney"

2021 American Transplant Congress
Long-Term Outcomes in Older Kidney Transplant Recipients from Older Donors
E. Cuadrado-Payán, E. Montagud-Marrahi, J. Casals-Urquiza, J. del Risco-Zevallos, D. Cucchiari, P. Ventura-Aguiar, I. Revuelta, G. Piñeiro, N. Esforzado, F. Cofan, J. Ugalde, J. Campistol, F. Oppenheimer, J. Torregrosa, F. Diekmann
Nephrology and Kidney Transplantation, Hospital Clínic de Barcelona, Barcelona, Spain
*Purpose: The age of patients referred for kidney transplantation has increased progressively. However, the precise influence of age on hard outcomes after transplantation is controversial*Methods:…
2021 American Transplant Congress
Pill Burden in Belatacept versus Tacrolimus-Based Immunosuppression
S. Gattis, L. Lakhani, A. Basu
Emory Healthcare, Atlanta, GA
*Purpose: Medication non-adherence is a major barrier amongst renal transplant recipients, and improvement can be seen after reduction in pill burden. Belatacept versus tacrolimus-based immunosuppression…
2021 American Transplant Congress
Bortezomib for Antibody-Mediated Rejection of Renal Transplant in Youth
L. Galea, J. Hewlett, J. Savant, S. Lopez, S. Amaral, B. Viteri
The Children’s Hospital of Philadelphia, Philadelphia, PA
*Purpose: The purpose of the study was to examine preliminary efficacy and tolerability of bortezomib, a protease inhibitor, in treatment-refractory antibody mediated rejection (AMR) in…
2021 American Transplant Congress
Prostate Cancer Mortality is Not Worse Among Kidney Transplant Recipients Compared to Dialysis Patients
N. Sarabu¹, W. Dong², S. M. Koroukian²
¹University Hospital Cleveland Medical Center, Cleveland, OH, ²Case Western Reserve University, Cleveland, OH
*Purpose: Recent recommendations from expert panel of American Society of Transplantation (AST) state that most patients with prostate cancer (PCa) do not need to wait…
2021 American Transplant Congress
COVID-19 in the Kidney Transplant Waitlist Population
A. C. Johnson¹, C. P. Larsen¹, H. Gebel², R. Bray²
¹Surgery, Emory University, Atlanta, GA, ²Pathology, Emory University, Atlanta, GA
*Purpose: Through banked serum samples from transplant candidates across Georgia, we characterize the prevalence, timing, and duration of SARS-CoV-2 seropositivity and investigate the impact on…
2021 American Transplant Congress
Contribution of T-bet Expressing CD27+ CD21- Activated Memory B Cells Poised for Plasma Cell Differentiation to Antibody-mediated Rejection of Kidney Transplants
K. Louis¹, E. Bailly¹, C. Macedo¹, B. Ramaswami¹, X. Gu¹, G. Chalasani¹, A. Zeevi¹, P. Randhawa¹, H. Singh², C. Lefaucheur³, D. Metes¹
¹Surgery, University of Pittsburgh, Pittsburgh, PA, ²Center for Systems immunology, Department of Immunology, University of Pittsburgh, Pittsburgh, PA, ³Human Immunology and Immunopathology, INSERM U976, Paris, France
*Purpose: Alloimmunity triggered by donor-specific antibodies (DSAs) and ensuing development of antibody-mediated rejection (ABMR) are detrimental to organ transplants. Yet, the cellular states underlying B…
2021 American Transplant Congress
The Australian and New Zealand Living Kidney Donor Profile Index
G. L. Irish¹, S. Chadban¹, N. Boudville², S. B. Campbell³, J. Kanellis⁴, P. A. Clayton¹
¹Australian and New Zealand Dialysis and Transplant Registry, South Australian Health and Medical Research Institute, Adelaide, Australia, ²Medical School, University of Western Australia, Perth, Australia, ³Department of Nephrology, Princess Alexandra Hospital, Brisbane, Australia, ⁴Department of Nephrology, Monash Health, Melbourne, Australia
*Purpose: Risk scores may aid risk quantification and decision-making in kidney transplantation. The Living Kidney Donor Profile Index (LKDPI) was developed to choose between living…
2021 American Transplant Congress
Nomogram of Quantity of Peripheral Cxcr5⁺Cd8⁺ T Cells, Aims to Predict Risk of De Novo Dsa in First-time Kidney Transplant Recipients
J. Zimmerer¹, M. Abdel-Rasoul², G. Bumgardner¹
¹OSU, Columbus, OH, ²Center for Biostatistics, OSU, Columbus, OH
*Purpose: We recently reported that peripheral CXCR5+CD8+ T cells are inversely associated with the risk of developing de novo DSA (dnDSA) in the first year…
2021 American Transplant Congress
Effect of Donor Glomerulosclerosis and Interstitial Fibrosis/Tubular Atrophy (IFTA) on Kidney Graft Survival: A Single Organ Procurement Organization (OPO) Data
P. Homkrailas¹, M. Hussain¹, G. M. Danovitch¹, K. Wheeler², S. Bunnapradist¹
¹Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, ²OneLegacy, Los Angeles, CA
*Purpose: The kidneys of deceased donors are often biopsied to evaluate transplant organ quality. A high percentage of GS is a leading cause of kidney…
2021 American Transplant Congress
Modifiable Barriers in Decision Making Around Living Donor Kidney Transplantation – A Rapid Scoping Review to Guide (DEAL-KD) Study
A. Ahmed¹, A. Winterbottom¹, S. Ahmed², J. Stoves³, S. Daga¹
¹Leeds Teaching Hospitals Trust, Leeds, United Kingdom, ²Division of Psychological and social Medicine, University of Leeds, Leeds, United Kingdom, ³Bradford Teaching Hospitals NHS Foundation Trust, Bradford, United Kingdom
*Purpose: Living donor kidney transplantation (LDKT) is the optimal modality of renal replacement therapy for patients with advanced renal disease; associated with superior recipient and…