Articles tagged "Kidney"

2022 American Transplant Congress
Impact of African American Race on Lcp-Tac Dosing and Clinical Outcomes
T. Sprague, F. Bartlett, J. Newman, S. Patel, N. Rao, E. Andrande, V. Rohan, D. Dubay, M. Casey, D. Taber
Medical University of South Carolina, Charleston, SC
*Purpose: The goal of this study was to assess the impact of African American (AA) race on the conversion ratio from Tac-IR to LCP-Tac, while…
2022 American Transplant Congress
Functional Recellularized Patient Derived Endothelium; A Human Vascular Graft Approach
H. Tejeda Mora¹, J. Willemse², Y. den Hartog¹, I. Schurink², M. M. Verstegen², J. de Jonge², R. C. Minnee², M. W. van den Hoogen², C. C. Baan¹, L. J. van der Laan², M. J. Hoogduijn¹
¹Transplant Institute - Internal Medicine, Erasmus Medical Center, Rotterdam, Netherlands, ²Transplant Institute - Department of Surgery, Erasmus Medical Center, Rotterdam, Netherlands
*Purpose: In transplantation, the endothelial lining is the first barrier between the donor organ and recipient immune system. Damaged endothelium exposes extracellular matrix (ECM) molecules…
2022 American Transplant Congress
Covid19 in Pediatric Kidney Transplant Recipients: Incidence, Outcomes, and Response to Vaccine
A. Moudgil, K. Sgambat, Y. Shi, M. Meyers, C. Petyak, L. Midgley
Nephrology, Children's National Med. Ctr., Washington, DC
*Purpose: At the onset of pandemic, no information was available on response of pediatric kidney transplant (PKTX) recipients to COVID19. When COVID19 vaccines became available,…
2022 American Transplant Congress
Transplant Rates Increased with Broader Distribution of Deceased Donor Kidneys
A. Robinson¹, K. Gauntt¹, A. Wilk¹, J. Kim², V. Casingal³, N. Turgeon⁴, M. Pavlakis⁵
¹UNOS, Richmond, VA, ²Surgery, Keck Medicine of USC, Los Angeles, CA, ³Carolinas Medical Center, Charlotte, NC, ⁴Dell Seton Medical Center at The University of Texas, Austin, TX, ⁵Beth Israel Deaconess Med Ctr, Boston, MA
*Purpose: The OPTN Kidney Transplantation Committee implemented a policy removing donation service area (DSA) and OPTN region from kidney allocation on 3/15/2021. In addition to…
2022 American Transplant Congress
RNA-Sequencing Analysis of Kidney Allografts Reveal Heightened NK Cell Activity in Chronic Active Antibody-Mediated Rejection
Y. Shah, E. Varma, S. Rahim, C. Li, C. Snopkowski, C. Hughes, D. M. Dadhania, S. Salvatore, S. V. Seshan, O. Elemento, M. Suthanthiran, T. Muthukumar
Weill Cornell Medicine, New York, NY
*Purpose: The role of NK cells is increasingly recognized in chronic active antibody mediated rejection (caABMR) of the kidney allograft. Treatment of caABMR is challenging…
2022 American Transplant Congress
Reasons for Kidney Transplant Patients to Have Outpatient Urine Cultures in the First Year Post-Transplant: An Analysis of the USRDS
V. Hemmige¹, E. Akalin², M. Kinkhabwala³
¹Montefiore Medical Center, Bronx, NY, ²Albert Einstein College of Medicine, Montefiore Medical Ctr, Bronx, NY, ³Albert Einstein College of Medicine, Bronx, NY
*Purpose: Urine cultures are frequently sent in the first year after kidney transplant, but the reasons that testing is done post-transplant is not well understood.…
2022 American Transplant Congress
Antibody Response to Sars-CoV-2 Vaccine Among Kidney Transplant Recipients: A Retrospective Cohort Study
H. Ishida¹, K. Unagami², K. Ishii³, T. Kanzawa², T. Yagisawa⁴, K. Tanabe², M. Furusawa²
¹Tokyo Women's, Tokyo, Japan, ²Tokyo Women's Medical University, Tokyo, Japan, ³Tokyo Wimen's Medical University, Tokyo, Japan, ⁴Department of Urology, Tokyo Women's Medical University, Tokyo, Japan
*Purpose: We examined a positivity of corona virus antibody in kidney transplant recipients who received two-doses BNT162B2 (mRNA) vaccination during the beginning 6 months in…
2022 American Transplant Congress
Abdominal Incision Technique Tailored to Patient’s Age May Reduce the Rate of Surgical Wound Complication After Unilateral Kidney Transplantation- A Preliminary Report
Y. AlSalmay, P. Bachul, B. Juengel, J. Kumar, A. Perez-Guttierez, R. Barth, J. Fung, P. Witkowski
University of Chicago, Chicago, IL
*Purpose: Previously, we compared the risk of abdominal wound complications after lateral rectus incision sheath (LRS) versus traditional Gibson incision in a retrospective analysis of…
2022 American Transplant Congress
Long Term Follow-Up of a Phase 2 Clinical Trial to Induce Tolerance in Living Donor Kidney Transplant Recipients
J. Leventhal¹, J. Galvin², J. Mathew³, L. Gallon³, D. Belshe⁴, M. Gibson⁴, K. Ravindra⁵, M. Horwitz⁶, S. Ildstad⁷
¹Feinberg School of Medicine, Northwestern University, Chicago, IL, ²University of Illinois Chicago, Chicago, IL, ³Northwestern University, Chicago, IL, ⁴Comprehensive Transplant Center, Northwestern University, Chicago, IL, ⁵Department of Surgery, Duke University Medical Center, Durham, NC, ⁶Adult Blood and Marrow Transplant Program, Duke University Medical Center, Durham, NC, ⁷Talaris Therapeutics Inc, Louisville, KY
*Purpose: 37 subjects were transplanted in a phase 2 protocol based upon tolerogenic CD8+/TCR-facilitating cells (FCR001) to induce tolerance in recipients of living donor kidney…
2022 American Transplant Congress
Donor-Derived Cell-Free DNA Across the Spectrum of Solid Organ Transplantation
S. R. Potter¹, J. Miles², K. Qu², R. Woodward², S. Dholakia²
¹Baylor Scott & White Health, Temple, TX, ²CareDx, Inc, Brisbane, CA
*Purpose: Donor-derived cell-free DNA (dd-cfDNA) is a robust and clinically useful analyte initially validated for kidney allograft surveillance. Emerging data support the utility of dd-cfDNA…