Articles tagged "Kidney transplantation"

2021 American Transplant Congress
Safety and Tolerability of Tacrolimus Extended-Release (astagraf Xl) in Hla Sensitized Kidney Transplant Recipients: A Single Center Experience
A. A. Vo, N. Ammerman, E. Huang, A. Peng, R. Najjar, S. Sethi, K. Lim, M. Gillespie, S. C. Jordan
Cedars Sinai Medical Ctr, Los Angeles, CA
*Purpose: Pill burden is a limitation in kidney transplant. Tacrolimus extended-release (Astagraf XL) is a once daily formulation approved for kidney transplantation. Increased compliance could…
2021 American Transplant Congress
Tolerability of Mycophenolate Mofetil in Elderly Kidney Transplant Recipients: A Retrospective Cohort Study
S. Witek¹, G. Malat², D. Sawinski², C. Sammons², C. LaFratte¹, A. Forte¹, R. Samudralwar¹, S. Lyle¹, J. Rashid¹, J. Trofe-Clark²
¹Dept of Pharmacy, Hospital of the Univ of Pennsylvania, Philadelphia, PA, ²Penn Transplant Institute, Hospital of the Univ of Pennsylvania, Philadelphia, PA
*Purpose: Optimal immunosuppression in elderly kidney transplant recipients (KTRs) is not well-defined, with MMF being poorly tolerated at standard doses. This study aims to compare…
2021 American Transplant Congress
Identifying Health-System Level Barriers and Facilitators to Living Donor Kidney Transplantation: A Comparative Case Study
A. Horton¹, M. Fortin², P. Nugus³, D. Landsberg⁴, M. Paquet², M. Cantarovich¹, S. Sandal¹
¹Nephrology, McGill University Health Centre, Montreal, QC, Canada, ²Nephrology, Centre Hospitalier de l’Université de Montréal, Montreal, QC, Canada, ³Family Medicine, McGill University, Montreal, QC, Canada, ⁴Nephrology, University of British Columbia, Vancouver, BC, Canada
*Purpose: Despite the well-known advantages of living donor kidney transplantation (LDKT), rates at many centers have stagnated or declined. In Canada, there are large interprovincial…
2021 American Transplant Congress
Early Experience with Broad Renal Genetic Testing in an Academic Transplant Center
E. Tantisattamo¹, K. Brossart², N. Ioannou², S. McCormick², P. R. Billings², H. Tabriziani²
¹Division of Nephrology, Hypertension and Kidney Transplantation, Division of Nephrology, Hypertension and Kidney Transplantation, Department of Medicine, University of California Irvine School of Medicine, Orange, CA, ²Natera, Inc., San Carlos, CA
*Purpose: Genetic testing is an emerging tool in kidney transplantation (KT), particularly to assess risk of recurrent disease in patients with KT and for selection…
2021 American Transplant Congress
Plasma Donor-Derived Cell-Free DNA Levels Risk-Stratify Kidney Allograft Injury with Isolated Transplant Glomerulitis
L. Bu¹, S. Anand², A. Pai³, J. S. Bromberg⁴, G. Gupta⁵, I. Moinuddin⁵, T. Alhamad⁶, V. Bowers⁷, S. Ghosh⁸, W. Tian⁸, E. Stites⁹
¹University of Minnesota, Minneapolis, MN, ²Intermountain Medical Center, Murray, UT, ³University of Texas McGovern Medical School, Houston, TX, ⁴University of Maryland School of Medicine, Baltimore, MD, ⁵Virginia Commonwealth University, Richmond, VA, ⁶Washington University in St. Louis, St. Louis, MO, ⁷Tampa General Hospital, Tampa, FL, ⁸CareDx, Brisbane, CA, ⁹University of Colorado, Aurora, CO
*Purpose: The Banff lesion Glomerulitis (g) characterizes the degree of microvascular glomerular inflammation. Some studies have demonstrated glomerulitis in the absence of C4d in association…
2021 American Transplant Congress
Outcomes of Kidney Transplantation in Patients with Congenital Anomalies of the Kidney and Urinary Tract
O. A. Oto¹, Y. Caliskan², H. Yazici¹, S. Mirioglu³, A. Dirim¹, N. Garayeva¹, S. Safak¹, E. Demir¹, Y. Ozluk⁴, A. Artan¹, A. Turkmen¹, K. Lentine²
¹Nephrology, Istanbul University, Istanbul, Turkey, ²Nephrology, Saint Louis University School of Medicine, Saint Louis, WA, ³Nephrology, Bezmialem Vakif University School of Medicine, Istanbul, Turkey, ⁴Pathology, Istanbul University, Istanbul, Turkey
*Purpose: We aimed to compare the long-term outcomes after kidney transplantation (KTx) in patients with congenital anomalies of the kidney and urinary tract (CAKUT) versus…
2021 American Transplant Congress
Non-Alcoholic Fatty Liver Disease in Non-Liver Transplant Patients
R. Claudio¹, C. Conceicao², K. Robichaux², A. Kumar¹, J. Buggs³, N. Kemmer⁴
¹Morsani College of Medicine, University of South Florida, Tampa, FL, ²Honors College, University of South Florida, Tampa, FL, ³Transplant Surgery, Tampa General Hospital, Tampa, FL, ⁴Transplant Hepatology, Tampa General Hospital, Tampa, FL
*Purpose: The global prevalence of non-alcoholic fatty liver disease (NAFLD) is rising at an alarming rate, driven in large part by an increased incidence of…
2021 American Transplant Congress
Genetic versus Self-reported African Ancestry and Kidney Allograft Outcome: Analysis of Two Large Multiethnic Urban Transplant Cohorts
F. Zanoni¹, D. Neugut¹, S. Mohan¹, A. Gharavi¹, B. Keating², K. Kiryluk¹
¹Department of Medicine, Division of Nephrology, Columbia University, New York, NY, ²Department of Surgery, Division of Transplantation, University of Pennsylvania, Philadelphia, PA
*Purpose: African-American (AA) kidney transplant recipients (KTx) have higher risk of rejection and failure. However, it is unknown to what extent the inferior outcomes in…
2021 American Transplant Congress
Panic in the Pandemic: A Medical Decision Analysis Examining When Kidney Transplant Programs Should Close
A. J. Vinson¹, B. Kiberd², K. Tennankore¹
¹Nova Scotia Health Authority Division of Nephrology, Departm, Halifax, NS, Canada, ²Dalhousie University, Halifax, NS, Canada
*Purpose: Pandemics greatly interfere with overall health care delivery as resources are diverted to combat the crisis. Kidney transplantation programs were closed temporarily during the…
2021 American Transplant Congress
Systematic Screening of Kidney Transplant Patients Points Towards Deficits in Neutralizing Antibody Capacity Against Sars-cov-2
V. Wijtvliet¹, K. K. Ariën², J. Mariën², B. Peeters³, R. Hellemans⁴, A. Massart⁴, S. Van Hees¹, P. Moons⁵, H. Theeten⁶, P. Van Damme⁶, H. Goossens⁷, B. Y. De Winter¹, K. J. Ledeganck¹, D. Abramowicz⁴
¹Laboratory of Experimental Medicine and Pediatrics, University of Antwerp, Antwerp, Belgium, ²Department of Biomedical Sciences, Institute of Tropical Medicine and University of Antwerp, Antwerp, Belgium, ³Department of Laboratory Medicine, Antwerp University Hospital, Antwerp, Belgium, ⁴Department of Nephrology and Hypertension, Antwerp University Hospital, Antwerp, Belgium, ⁵Biobank, Antwerp University Hospital, Antwerp, Belgium, ⁶Centre for the Evaluation of Vaccination, Vaccine and Infectious Disease Institute, University of Antwerp, Antwerp, Belgium, ⁷Department of Medical Microbiology, Vaccine & Infectious Disease Institute, University of Antwerp, Antwerp, Belgium
*Purpose: The majority of kidney transplant recipients (KTR) is able to develop SARS-CoV-2 antibodies (Abs). Little is known about the virus neutralizing capacity of these…