Articles tagged "Kidney transplantation"

2021 American Transplant Congress
Sharing Under KAS – What is the Impact According to KDPI?
M. Jacobs, R. Stratta, C. Jay
Wake Forest Baptist Health, Winston Salem, NC
*Purpose: The new Kidney Allocation System (KAS) implemented in 2014 was designed to facilitate sharing of kidneys due to changes in prioritization of highly sensitized…
2021 American Transplant Congress
Transplant Center Volume in High-risk Donors are Associated with Graft and Patient Survival
M. A. Merzkani, H. Murad, M. Mattu, M. Wang, V. Hu, S. Chang, T. Alhamad
Transplant, Washington University, Saint Louis, MO
*Purpose: Evaluation of high-risk kidney donors in transplant centers involves an intensive assessment of the individual risks and selection of appropriate recipients. Understandably, this requires…
2021 American Transplant Congress
Association of Kidney Function with Patient Reported Outcomes After Kidney Transplantation
G. S. Kochar, S. A. Rega, I. D. Feurer, A. Dreher, H. Schaefer, D. Shaffer, R. C. Forbes, C. W. Pinson, B. P. Concepcion
Nephrology, Vanderbilt University Medical Center, Nashville, TN
*Purpose: Our study aimed to determine the association of posttransplant eGFR with patient reported outcomes (PROs) and, specifically, the risk of reduced health-related quality of…
2021 American Transplant Congress
The Seattle Heart Failure Model is a Predictor of Mortality After Kidney Transplant in Patients with End Stage Renal Disease and Heart Impairment
A. Perez-Gutierrez¹, P. J. Bachul², D. N. Danz³, B. Juengel², M. Josephson², J. Fung², P. Witkowski², B. Chung⁴, Y. Becker²
¹Surgery, University of Chicago, Chicago, IL, IL, ²Surgery, University of Chicago, Chicago, IL, ³Economics, University of Pittsburgh, Pittsburgh, IL, ⁴Cardiology, University of Chicago, Chicago, IL
*Purpose: Cardiovascular disease is the main cause of mortality after kidney transplantation. Many patients with ESRD have heart failure that is attributed to fluid overload.…
2021 American Transplant Congress
Avoiding Tacrolimus Under- and Overexposure with a Dosing Algorithm for Renal Transplant Recipients: A Single Arm Prospective Intervention Trial
M. I. Francke¹, L. M. Andrews², H. L. Le², J. van de Wetering¹, M. C. Clahsen-van Groningen³, T. van Gelder⁴, R. H. van Schaik⁵, B. van der Holt⁶, B. C. de Winter², D. A. Hesselink¹
¹Internal medicine, nephrology and transplantation, Erasmus MC, University Medical Center, Rotterdam, Netherlands, ²Hospital Pharmacy, Erasmus MC, University Medical Center, Rotterdam, Netherlands, ³Pathology, Erasmus MC, University Medical Center, Rotterdam, Netherlands, ⁴Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, Netherlands, ⁵Clinical Chemistry, Erasmus MC, University Medical Center, Rotterdam, Netherlands, ⁶Hematology, Erasmus MC, University Medical Center, Rotterdam, Netherlands
*Purpose: Bodyweight-based tacrolimus dosing followed by therapeutic drug monitoring is standard clinical care after renal transplantation. However, after transplantation, a meagre 38% of patients is…
2021 American Transplant Congress
Awareness of Teratogenic Potential of Mycophenolic Acid Products and Pregnancy Outcomes in Kidney Transplant Recipients
S. Rao¹, L. Coscia², A. Yusuf², S. Constantinescu³, M. J. Moritz⁴
¹Nephrology, University of Virginia Heath System, Charlottesville, VA, ²Transplant Pregnancy Registry International, Philadelphia, PA, ³Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, ⁴Surgery, Lehigh Valley Health Network, Allentown, PA
*Purpose: In 2006, Transplant Pregnancy Registry International (TPRI) reported teratogenic effects of mycophenolic acid products (MPA) in pregnancies in transplant recipients. This resulted in black…
2021 American Transplant Congress
Initial Experience with Single-port Robotic-assisted Kidney Transplantation
M. Eltemamy, A. Aminsharifi, Y. Lin, Z. Schwen, M. Abou Zeinab, V. Krishnamurthi, D. Goldfarb, A. Wee, J. Kaouk
Cleveland Clinic, Cleveland, OH
*Purpose: Early experiences with multi-port robotic kidney transplantation have demonstrated a potential reduction in complications and improved convalescence while maintaining equivalent functional outcomes relative to…
2021 American Transplant Congress
Maternal Perinatal Condition and Neonatal Growth and Development After Renal Transplantation
X. Feng, T. Song, Q. Zhong, J. Zeng, X. Wang, Y. Fan, Z. Huang, T. Lin
Department of Urology, Institute of Urology, Organ Transplantation Center, West China Hospital, Sichuan University, Chengdu, China
*Purpose: Although pregnancy and delivery after kidney transplantation have been reported in many studies , it is still little known about growth and development of…
2021 American Transplant Congress
Detection of Rejection in Kidney Transplant Patients Using an Algorithm That Combines Donor Fraction and Absolute Donor-derived Cell-free DNA
S. Bunnapradist¹, E. Ahmed², M. Maninder², Z. P. Demko², P. R. Billings², H. Tabriziani², P. Gauthier³
¹David Geffen Sch of Med @ UCLA, Los Angeles, CA, ²Natera, Inc., San Carlos, CA, ³Natera, Inc., Los Angeles, CA
*Purpose: Donor-derived cell-free DNA (dd-cfDNA) in the plasma of renal allograft patients is a clinically validated biomarker for allograft injury and rejection. Several dd-cfDNA assays…
2021 American Transplant Congress
Characterization of Chronic Renal Allograft Dysfunction at Single Cell Resolution
C. Kuscu¹, C. Kuscu², A. Shetty³, M. Talwar⁴, J. Eason², D. G. Maluf⁵, V. Mas⁶
¹Surgery, James D Eason Transplant Institute, UTHSC, Memphis, TN, ²Surgery, James D Eason Transplant Institute, Memphis, TN, ³Institute for Genome Sciences, School of Medicine, University of Maryland, Baltimore, MD, ⁴Nephrology, James D Eason Transplant Institute, Memphis, TN, ⁵Surgery, Program in Transplantation - University of Maryland, Baltimore, MD, ⁶Surgery, Division of Surgical Science - University of Maryland, Baltimore, MD
*Purpose: Chronic allograft dysfunction (CAD) is one of the major complications after kidney transplantation. Hereby, we aim to assess the molecular and cellular mechanism of…