Articles tagged "Kidney transplantation"

2022 American Transplant Congress
Impact of Cold Ischemia Times on 1 Year Kidney Transplant Outcomes
T. Fletchinger, L. Burdine
Department of Surgery, University of Arkansas for Medical Sciences, Little Rock, AR
*Purpose: Recent organ allocation changes have increased travel and subsequent cold ischemia times (CIT) of kidney allografts. We sought to investigate the impact of prolonged…
2022 American Transplant Congress
Clusterin Protects Kidney Transplants from Ischemia-Reperfusion Injury by Modulating Neutrophil Infiltration
Y. Shim¹, R. Fan², N. Dvorina², K. McCrae¹, B. William²
¹Cardiovascular and Metabolic Sciences, Cleveland Clinic Lerner Research Institute, Cleveland, OH, ²Inflammation and Immunity, Cleveland Clinic Lerner Research Institute, Cleveland, OH
*Purpose: Ischemia-reperfusion injury (IRI) is inevitable during organ transplantation. Clusterin (CLU) has shown to be protective in IRI. Supplementation of storage solution with recombinant CLU…
2022 American Transplant Congress
QSant, a Novel Urine Test Monitors Recovery of Allograft Injury After DGF
S. Ghosh¹, H. Tedesco², R. Sarwal¹, N. Titzler¹, W. Yazar¹, M. Nakamura², J. Pestana², M. Sarwal¹
¹Nephrosant, Brisbane, CA, ²Hospital do Rim, Sao Paolo, Brazil
*Purpose: We evaluate urine QSant assay to non-invasively monitor recovery of allograft injury, post delayed graft function(DGF).*Methods: 65 HLA-DR matched, renal allograft recipients, on TAC/MMF/prednisone…
2022 American Transplant Congress
Implementation of Modified Multi-Point Screening in Selection Criteria for Kidney Transplant Candidates
M. E. Welborn, S. Thuppal, K. Delfino, R. Bounds, M. Hazelrigg, M. R. Garfinkel
Division of General Surgery, Department of Surgery, Southern Illinois University, Springfield, IL
*Purpose: In 2016, the Springfield Memorial Hospital (SMH) Transplant Program implemented a modified assessment for all renal transplant candidates undergoing evaluation in an effort to…
2022 American Transplant Congress
Does the New Kidney Transplant Allocation System Impact Delayed Graft Function Rates After Kidney Transplantation?
P. N. Chotai¹, F. Siddiqui², A. Logan³, K. Washburn⁴, A. Schenk⁵, A. Limkemann³
¹Division of Transplantation, Department of General Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, ²Ohio State University, Bloomfield, NJ, ³The Ohio State University Wexner Medical Center, Columbus, OH, ⁴The Ohio State University, Columbus, OH, ⁵Ohio State University Wexner Medical Center, Bexley, OH
*Purpose: The Organ Procurement and Transplantation Network (OPTN) implemented a new, distance based, kidney transplant allocation system (nKAS) for recipients of deceased donor kidney transplant…
2022 American Transplant Congress
Renal Allograft Outcomes of Very High KDPI vs High KDPI Donor Kidneys
R. Rattanavich, R. Villicana
Transplant Nephrology, Transplant Institute Loma Linda University, Loma Linda, CA
*Purpose: Since KDPI > 85 donor kidneys have been commonly used among older recipients, renal allograft outcomes of very high KDPI (≥95) donors have been…
2022 American Transplant Congress
Defects in Kim-1 Do Not Result In Delayed Graft Function After Kidney Transplantation
R. S. Suri¹, J. Lee², M. Ban³, B. Shrum², O. Z. Ismail⁴, S. Leckie⁵, A. McIntyre³, Q. Xu⁶, S. H. Lee², S. de Chickera², R. A. Hegele², L. Gunaratnam²
¹Research Institute of the McGill University Health Center, Montreal, QC, Canada, ²Schulich School of Medicine and Dentistry, Western University, Lodnon, ON, Canada, ³Robarts Research Institute, Lodnon, ON, Canada, ⁴University of Alberta, Edmonton, AB, Canada, ⁵London Health Sciences Centre, Lodnon, ON, Canada, ⁶University of Pittsburg Medical Center, Pittsburg, PA
*Purpose: Tissue repair is critical to restore organ function after ischemia-reperfusion injury (IRI) during transplantation. During renal injury, upregulation of kidney injury molecule-1 (KIM-1) transforms…
2022 American Transplant Congress
Glucose Variability in Kidney Transplantation: Pre-Transplant and Post-Transplant Continuous Glucose Monitoring
E. Jo¹, A. Han², S. Min², J. Ha³, H. Lee⁴, A. Cho⁵
¹Surgery, Seoul National University Hospital, Seoul, Korea, Republic of, ²Seoul National University College of Medicine, Seoul, Korea, Republic of, ³Seoul Nat'l Univ. College of Medicine, Seoul, Korea, Republic of, ⁴Seoul National University Hospital, Seoul, Korea, Republic of, ⁵Surgery, Seoul National University College of Medicine, Seoul, Korea, Republic of
*Purpose: Continuous glucose monitoring (CGM) provides a 24-hour view of glucose values and information on glycemic variability and additional indices such as the glucose management…
2022 American Transplant Congress
Associated Factors to Physical Inactivity of Kidney Transplant Patients: Subproject of ADHERE Brazil Multicenter Study
E. S. Sertorio¹, F. A. Colugnati¹, K. Denhaerynck², S. De Smet³, J. O. Medina⁴, M. M. Reboredo⁵, S. De Geest², H. Sanders-Pinheiro¹, T. ADHERE BRAZIL Study team¹
¹Nephrology, Federal University of Juiz de Fora, Juiz de Fora, Brazil, ²Department of Public Health, Institute of Nursing Science, University of Basel, Basel, Switzerland, ³Transplant Research Group, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, ⁴Nephrology, Hsopital do Rim, Federal University of São Paulo, São Paulo, Brazil, ⁵Pneumology, Federal University of Juiz de Fora, Juiz de Fora, Brazil
*Purpose: Even though regular physical activity is a current recommendation for kidney transplant recipients (KTR), results from ADHERE Brazil study revealed a high prevalence of…
2022 American Transplant Congress
Long-Term (>1 Year) Rejection Free Graft Survival of Kidney Xenografts with Triple Xenoantigen Knockout and Multiple Human Transgenes in Cynomolgus Monkeys
T. Hirose¹, G. Lassiter¹, D. Ma¹, A. D'Attilio¹, I. Rosales¹, D. Cloonan¹, R. Matheson¹, R. Colvin¹, W. Qin², Y. Kan², J. Layer², R. Anand², V. Paragas², L. Queroz², X. Tan², I. Kohnle², K. Stiede², K. Hall², M. Youd², M. Curtis², J. Markmann¹, T. Kawai¹
¹Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, ²eGenesis Inc, Cambridge, MA
*Purpose: Pigs with deletion of 3 carbohydrate xenoantigens (triple knock-out, TKO) are expected to be optimal donors for human xenotransplantation. We have previously shown that…

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