Articles tagged "Kidney transplantation"

2021 American Transplant Congress
Initial Experience with Growth Hormone Receptor Knockout in Pig-to-Baboon Kidney Transplantation: Effect on Ureteric Viability and Kidney Growth
C. Hansen-Estruch¹, H. Iwase¹, A. Jagdale¹, T. Yamamoto¹, M. H. Bikhet¹, J. Foote², H. Hara¹, D. Anderson¹, P. Porrett¹, D. Eckhoff¹, D. Ayares³, W. Eyestone³, J. Locke¹, D. K. Cooper¹
¹Xenotransplantation Program, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL, ²Department of Microbiology and Animal Resources Program, University of Alabama at Birmingham, Birmingham, AL, ³Revivicor, Blacksburg, VA
*Purpose: The purpose of this study was to report outcomes of pig-to-baboon renal transplants using a novel growth hormone receptor knockout (GHRKO) organ-source pig created…
2021 American Transplant Congress
Dietary Intake and Mycophenolate Mofetil-related Diarrhea Following Kidney Transplantation
G. Onyeaghala¹, L. Teigen², B. Guo², Y. Doronin¹, M. Al-Kofahi², B. Wu², W. Guan², C. Staley², S. Riad², A. Matas², R. Remmel², W. Oetting², C. Dorr¹, P. Jacobson², A. Israni¹
¹Nephrology, Hennepin Healthcare Research Institute, Minneapolis, MN, ²University of Minnesota, Minneapolis, MN
*Purpose: The treatment of Mycophenolate mofetil (MMF) related diarrhea in kidney transplants recipients involves providing lower MMF doses more frequently to maintain the same daily…
2021 American Transplant Congress
Torque Teno Virus Load Predicts Allograft Rejection but Not Viral Infection After Kidney Transplantation; A Cohort Joint Modelling Study
A. L. van Rijn¹, H. F. Wunderink², I. A. Sidorov¹, C. S. de Brouwer¹, A. C. Kroes¹, H. Putter³, A. P. de Vries⁴, J. I. Rotmans⁴, M. C. Feltkamp¹
¹Medical Microbiology, Leiden University Medical Center, Leiden, Netherlands, ²Medical Microbiology, University Medical Center Utrecht, Utrecht, Netherlands, ³Medical Statistics, Leiden University Medical Center, Leiden, Netherlands, ⁴Internal Medicine, Leiden University Medical Center, Leiden, Netherlands
*Purpose: The main challenge of immunosuppressive therapy after solid organ transplantation is to find the optimal dose regimen, and prevent allograft rejection as well as…
2021 American Transplant Congress
Covid-19 in a Kidney Transplant Patient Associated with Collapsing Glomerulopathy
W. Hninn, M. Merzkani, H. Murad, A. Malone, A. Java, G. Rajashekar, R. Delos Santos, T. Alhamad
Washington University School of Medicine, St. Louis, MO
*Purpose: Coronavirus- 19 is a novel virus with various clinical presentations ranging from a cold to severe acute respiratory syndrome. However, little is known about…
2021 American Transplant Congress
Evaluation of Low Dose Famciclovir as Herpes Simplex Virus and Varicella Zoster Virus Prophylaxis in Cytomegalovirus Low Risk Solid Organ Transplant Recipients
M. Cote, A. Cubley, C. Rogers, S. Shao, C. N. Kotton
Massachusetts General Hospital, Boston, MA
*Purpose: Famciclovir is recommended for herpes simplex virus (HSV) and varicella-zoster virus (VZV) prophylaxis in cytomegalovirus (CMV) low risk (both donor and recipient CMV seronegative)…
2021 American Transplant Congress
Cytomegalovirus Infection Among Adult Kidney Transplant Recipients: Findings From the USRDS-medicare Linked Database Study
A. Raval¹, M. Ganz², S. Alam², Y. Tang¹, C. Santos³
¹Merck & Co., Inc., Rahway, NJ, ²Evidera-PPD, Waltham, MA, ³Rush University Medical Center, Chicago, IL
*Purpose: Cytomegalovirus infection (CMVi) is a frequent complication and significant cause of morbidity and mortality after kidney transplantation (KT). However, there are limited recent national…
2021 American Transplant Congress
Sharing Under KAS – What is the Impact According to KDPI?
M. Jacobs, R. Stratta, C. Jay
Wake Forest Baptist Health, Winston Salem, NC
*Purpose: The new Kidney Allocation System (KAS) implemented in 2014 was designed to facilitate sharing of kidneys due to changes in prioritization of highly sensitized…
2021 American Transplant Congress
Transplant Center Volume in High-risk Donors are Associated with Graft and Patient Survival
M. A. Merzkani, H. Murad, M. Mattu, M. Wang, V. Hu, S. Chang, T. Alhamad
Transplant, Washington University, Saint Louis, MO
*Purpose: Evaluation of high-risk kidney donors in transplant centers involves an intensive assessment of the individual risks and selection of appropriate recipients. Understandably, this requires…
2021 American Transplant Congress
Association of Kidney Function with Patient Reported Outcomes After Kidney Transplantation
G. S. Kochar, S. A. Rega, I. D. Feurer, A. Dreher, H. Schaefer, D. Shaffer, R. C. Forbes, C. W. Pinson, B. P. Concepcion
Nephrology, Vanderbilt University Medical Center, Nashville, TN
*Purpose: Our study aimed to determine the association of posttransplant eGFR with patient reported outcomes (PROs) and, specifically, the risk of reduced health-related quality of…
2021 American Transplant Congress
The Seattle Heart Failure Model is a Predictor of Mortality After Kidney Transplant in Patients with End Stage Renal Disease and Heart Impairment
A. Perez-Gutierrez¹, P. J. Bachul², D. N. Danz³, B. Juengel², M. Josephson², J. Fung², P. Witkowski², B. Chung⁴, Y. Becker²
¹Surgery, University of Chicago, Chicago, IL, IL, ²Surgery, University of Chicago, Chicago, IL, ³Economics, University of Pittsburgh, Pittsburgh, IL, ⁴Cardiology, University of Chicago, Chicago, IL
*Purpose: Cardiovascular disease is the main cause of mortality after kidney transplantation. Many patients with ESRD have heart failure that is attributed to fluid overload.…