Articles tagged "Kidney transplantation"

2021 American Transplant Congress
Recurrence and Outcome of Anti-GBM Glomerulonephritis After Kidney Transplantation: A Belgian Multicenter Study
S. Coche
Nephrology, Cliniques Universitaires Saint-Luc, Brussels, Belgium
*Purpose: Recurrence of anti-glomerular basement membrane (anti-GBM) glomerulonephritis (GN) in the kidney graft is a rare event, described in limited case reports and registry analysis.…
2021 American Transplant Congress
Impact of Bacterial Infection on HLA Allosensitization Among Kidney Recipients on the Waitlist
D. P. Cina¹, K. R. Sherwood², S. Dobrer², J. Wong³, F. Fenninger², M. Kadatz⁴, P. Keown⁴, J. Lan⁴
¹Department of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada, ²University of British Columbia, Vancouver, BC, Canada, ³Department of Laboratory Medicine, Vancouver General Hospital, Vancouver, BC, Canada, ⁴Department of Nephrology, University of British Columbia, Vancouver, BC, Canada
*Purpose: The clinical relevance of HLA allosensitization associated with bacterial infection remains poorly defined. The primary objective of this study is to determine the incidence,…
2021 American Transplant Congress
Needs of People with Kidney Transplantation During the Covid 19 Pandemic and Its Confinement, and the Role of Communication Technologies Through the “Patient Experience”
I. Revuelta¹, E. Palou², R. Scandurra³, F. Oppenheimer¹, F. Diekmann¹, J. Escarrabill², B. Bayés¹
¹Department of Nephrology and Kidney Transplant, Hospital Clinic, Barcelona, Spain, ²Chronic care program and patient experience, Hospital Clinic, Barcelona, Spain, ³Department of Statistics, Universidad Autónoma de Barcelona, Barcelona, Spain
*Purpose: During the COVID-19 pandemic, healthcare services have focused on the care of acute processes and there is a risk of not meeting the needs…
2021 American Transplant Congress
Bamlanivimab for Covid-19 in Kidney Transplant Patients
M. Y. Jan, S. El-Sayegh, M. S. Yaqub, D. P. Mishler, O. Adebiyi, M. D. Anderson, T. E. Taber, A. Sharfuddin
Nephrology, Indiana University School of Medicine, Indianapolis, IN
*Purpose: Treatment options for patients with COVID 19 have limited efficacy in reducing severity and duration of viral symptoms as well as progression to severe…
2021 American Transplant Congress
Construction of a Waiting Time Predictive Model for Kidney Transplant with Deceased Donor in the State of São Paulo
J. Silva¹, M. Contti¹, M. Valiatti¹, H. Nga¹, G. Santos¹, M. Perosa², G. Ferreira³, L. Modelli de Andrade¹
¹UNESP, Botucatu, Brazil, ²Hospital Leforte, São Paulo, Brazil, ³Santa Casa de Juiz de Fora, Juiz de Fora, Brazil
*Purpose: Chronic kidney disease is an important public health problem and kidney transplant is the therapy of choice when possible. The transplant system in the…
2021 American Transplant Congress
Peripheral Blood Inflammatory Chemokines Uncover Rejection in the Absence of Histological Lesions
E. Van Loon¹, T. Barba², B. Lamarthée¹, A. Senev¹, O. Thaunat², D. Schols³, M. Naesens¹
¹Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, ²Department of Transplantation, Nephrology and Clinical Immunology, Edouard Herriot Hospital Lyon, Lyon, France, ³Laboratory of Virology and Chemotherapy, KU Leuven, Leuven, Belgium
*Purpose: Cytokines and chemokines play a critical role in the pathophysiology of allograft rejection, but the relation of peripheral blood cytokine expression profiles to clinical…
2021 American Transplant Congress
Outcomes of Kidney Transplant Recipients (KTRs) Comparing Brain Dead Donors’ vs Donation After Cardiac Death Stratified by KDPI, Focus on Marginal Kidneys: A UNOS Database Analysis
B. Chopra¹, K. K. Sureshkumar¹, D. Rajasundaram², E. C. Rodrigo³
¹Allegheny Health Network, Pittsburgh, PA, ²UPMC, Pittsburgh, PA, ³University Hospital Marqués de Valdecilla, Santander, Spain
*Purpose: In deceased donor kidney transplantation (DDKT), donation after cardiac death (DCD) is associated with increased cytokine release and renal tubular injury with consequent increase…
2021 American Transplant Congress
The Benefits of Sharing Non-Directed Donors Nationally Through Paired Exchange
J. Verbesey¹, A. G. Thomas², A. D. Waterman³, J. Vucci¹, G. Vranic¹, A. Gilbert¹, S. Ghasemian¹, M. Cooper¹
¹Georgetown University Hospital, Washington, DC, ²Johns Hopkins University School of Medicine, Baltimore, MD, ³UCLA, Los Angeles, CA
*Purpose: Non-directed donors (NDDs) are a valuable resource that can “unlock” incompatible transplants. Recent advances in paired kidney exchange (PKE) suggest that NDDs may facilitate…
2021 American Transplant Congress
Risk Stratification of Kidney Transplant Patients According to the Different Level of HLA-DQ Disparities
A. Senev¹, A. R. Tambur², M. Naesens¹
¹Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, ²Northwestern University, Chicago, IL
*Purpose: It is becoming clear that de novo donor-specific antibodies (dnDSA) against HLA-DQ are the most prevalent and the leading cause of chronic antibody-mediated rejection…
2021 American Transplant Congress
Donor-Derived Cell-Free DNA Levels Risk-Stratify Polyoma BK Viremia and Associated Clinical Events After Kidney Transplantation – Preliminary Results from ADMIRAL Study
A. Pai¹, L. Bu², J. S. Bromberg³, G. Gupta⁴, I. Moinuddin⁴, T. Alhamad⁵, V. Bowers⁶, S. Ghosh⁷, W. Tian⁷, E. Stites⁸, S. Anand⁹
¹University of Texas McGovern Medical School, Houston, TX, ²University of Minnesota, Minneapolis, MN, ³University of Maryland School of Medicine, Baltimore, MD, ⁴Virginia Commonwealth University, Richmond, VA, ⁵Washington University in St. Louis, St. Louis, MO, ⁶Tampa General Hospital, Tampa, FL, ⁷CareDx, Brisbane, CA, ⁸University of Colorado, Aurora, CO, ⁹Intermountain Medical Center, Murray, UT
*Purpose: The threshold of 10,000 copies for blood Quant BK PCR has been used as a surrogate for BK nephropathy (BKN) in kidney transplant recipients…