Articles tagged "Kidney transplantation"

2021 American Transplant Congress
Comparing Bortezomib Protocol versus IVIG/Rituximab in the Treatment of Antibody Mediated Rejection (AMR) in Kidney Transplantation
V. M. Lowery¹, A. Centeno¹, T. Harrison¹, P. Cabrera¹, A. Mattiazzi²
¹Pharmacy, Jackson Memorial Hospital/Miami Transplant Institute, Miami, FL, ²Nephrology & Hypertension, Miami Transplant Institute, Jackson Memorial Hospital/Miami Transplant Institute, Miami, FL
*Purpose: To compare outcomes of historical treatment of AMR [PLEX + IVIG + Rituximab] with addition of bortezomib, along with characterizing safety parameters aimed at…
2021 American Transplant Congress
Association of Donor-Derived Cell-Free DNA with Severity of Interstitial Fibrosis and Cortical Atrophy Lesions Following Kidney Transplantation
L. Bu¹, E. Stites², V. Bowers³, T. Alhamad⁴, J. S. Bromberg⁵, G. Gupta⁶, I. Moinuddin⁶, S. Ghosh⁷, W. Tian⁷, A. Pai⁸, S. Anand⁹
¹University of Minnesota, Minneapolis, MN, ²University of Colorado, Aurora, CO, ³Tampa General Hospital, Tampa, FL, ⁴Washington University in St. Louis, St. Louis, MO, ⁵University of Maryland School of Medicine, Baltimore, MD, ⁶Virginia Commonwealth University, Richmond, VA, ⁷CareDx, Brisbane, CA, ⁸University of Texas McGovern Medical School, Houston, TX, ⁹Intermountain Medical Center, Murray, UT
*Purpose: The most common cause of kidney transplant (KT) failure is the poorly characterized histopathologic entity “interstitial fibrosis and tubular atrophy” (IFTA). There are no…
2021 American Transplant Congress
Removal of Race Factor in Egfr Decreases Disparities in Preemptive Listing for Kidney Transplantation
Y. Al-Salmay, N. Jandovitz, M. Abate, A. Baez, E. Molmenti, A. Fahmy, N. Breslin, L. Teperman, V. Nair
Organ Transplantation, Northwell Health, Manhasset, NY
*Purpose: GFR < 20 is required for kidney transplant listing. The Chronic Kidney Disease-Epidemiology Collaboration (CKD-EPI) and the Modification of Diet in Renal Disease (MDRD)…
2021 American Transplant Congress
Offer Acceptance Models for Various Endpoints: Initial Response, Final Response, and Conversion from Provisional Yes to Yes
C. Martinez, M. Stuart, A. Placona
United Network for Organ Sharing, Richmond, VA
*Purpose: Offer acceptance models are routinely used for program evaluation and academic research, but the focus tends to be on modelling the final offer response.…
2021 American Transplant Congress
Covid-19 in Renal Transplant Recipients: Experience of Lithuania
M. Miglinas, M. M. Janušaitė, E. Ašakienė, L. Vareikienė
Nephrology, Vilnius University Santaros clinics, Vilnius, Lithuania
*Purpose: Renal transplant recipients are at increased susceptibility to many viral infections, including coronavirus disease 2019 (COVID-19). The purpose of this review is to define…
2021 American Transplant Congress
Renal Transplant Outcomes of Kidney-only vs. Multi-organ Deceased Donors
J. Espinales¹, Z. C. Giffen¹, D. Schneider², R. James³, N. Koizumi³, O. Ekwenna¹, J. Ortiz⁴
¹University of Toledo Medical Center, Toledo, OH, ²UC Irvine School of Medicine, Irvine, CA, ³George Mason University, Arlington, VA, ⁴Albany Medical Center, Albany, NY
*Purpose: We sought to determine the relative outcomes of kidneys from kidney-only or multi-organ deceased donors.*Methods: Scientific Registry of Transplant Recipients data from 2010-2019 were…
2021 American Transplant Congress
A Multimodal Interrogation of Human Renal Allografts
D. Dadhania¹, R. Ding¹, H. Xu², C. Lee¹, C. Snopkowski¹, T. Salinas¹, T. Muthukumar¹, J. Lee¹, R. Woodward², M. Grskovic², S. Dholakia², M. Suthanthiran¹
¹Weill Cornell Medicine - NYPH, New York, NY, ²CareDx, New York, NY
*Purpose: Development and validation of noninvasive biomarkers of kidney allograft rejection should improve transplant outcomes. CTOT-04 study validated urinary cell mRNA signature (CTOT04-Sig) for T-cell…
2021 American Transplant Congress
Successful Outcomes from Selected Akin3 Donors Requiring Renal Replacement: Avenue for Increase in Organ Utilization
P. Budhiraja¹, R. L. Heilman¹, M. L. Smith², H. A. Khamash¹, L. Kodali¹, A. A. Moss³, A. K. Mathur³, C. Jadlowiec³, K. S. Reddy³
¹Medicine, Mayo Clinic, Phoenix, AZ, ²Pathology, Mayo Clinic, Phoenix, AZ, ³Surgery, Mayo Clinic, Phoenix, AZ
*Purpose: Our aim was to determine outcomes with transplanting kidneys from deceased donors with severe acute kidney injury requiring acute renal replacement therapy.*Methods: We included…
2021 American Transplant Congress
Right Kidneys and Kidneys with Complex Anatomy are More Likely to be Transplanted to the Waiting List in a National Kidney Paired Donation Program
N. Osbun¹, A. Thomas², A. Waterman³, J. Veale¹, D. Segev², D. Leeser⁴
¹Urology, University of California Los Angeles, Los Angeles, CA, ²Johns Hopkins University, Baltimore, MD, ³University of California Los Angeles, Los Angeles, CA, ⁴East Carolina University, Greenville, NC
*Purpose: In the era of laparoscopic donor nephrectomy, there is a preference for left kidneys with a single renal artery. In paired exchange, the receiving…
2021 American Transplant Congress
Low Immunogenic Donors Improve Kidney Transplant Survival in Sensitized Recipients
D. Bekbolsynov¹, R. Green², B. Mierzejewska¹, M. Rees¹, S. Stepkowski¹
¹University of Toledo, Toledo, OH, ²Bowling Green State University, Bowling Green, OH
*Purpose: Our previous results showed that low immunogenicity (IM) donors improved kidney allograft survival in non-sensitized recipients. Herein, we examined how the level of peak…