Articles tagged "Kidney transplantation"

2022 American Transplant Congress
Defects in Kim-1 Do Not Result In Delayed Graft Function After Kidney Transplantation
R. S. Suri¹, J. Lee², M. Ban³, B. Shrum², O. Z. Ismail⁴, S. Leckie⁵, A. McIntyre³, Q. Xu⁶, S. H. Lee², S. de Chickera², R. A. Hegele², L. Gunaratnam²
¹Research Institute of the McGill University Health Center, Montreal, QC, Canada, ²Schulich School of Medicine and Dentistry, Western University, Lodnon, ON, Canada, ³Robarts Research Institute, Lodnon, ON, Canada, ⁴University of Alberta, Edmonton, AB, Canada, ⁵London Health Sciences Centre, Lodnon, ON, Canada, ⁶University of Pittsburg Medical Center, Pittsburg, PA
*Purpose: Tissue repair is critical to restore organ function after ischemia-reperfusion injury (IRI) during transplantation. During renal injury, upregulation of kidney injury molecule-1 (KIM-1) transforms…
2022 American Transplant Congress
Glucose Variability in Kidney Transplantation: Pre-Transplant and Post-Transplant Continuous Glucose Monitoring
E. Jo¹, A. Han², S. Min², J. Ha³, H. Lee⁴, A. Cho⁵
¹Surgery, Seoul National University Hospital, Seoul, Korea, Republic of, ²Seoul National University College of Medicine, Seoul, Korea, Republic of, ³Seoul Nat'l Univ. College of Medicine, Seoul, Korea, Republic of, ⁴Seoul National University Hospital, Seoul, Korea, Republic of, ⁵Surgery, Seoul National University College of Medicine, Seoul, Korea, Republic of
*Purpose: Continuous glucose monitoring (CGM) provides a 24-hour view of glucose values and information on glycemic variability and additional indices such as the glucose management…
2022 American Transplant Congress
Associated Factors to Physical Inactivity of Kidney Transplant Patients: Subproject of ADHERE Brazil Multicenter Study
E. S. Sertorio¹, F. A. Colugnati¹, K. Denhaerynck², S. De Smet³, J. O. Medina⁴, M. M. Reboredo⁵, S. De Geest², H. Sanders-Pinheiro¹, T. ADHERE BRAZIL Study team¹
¹Nephrology, Federal University of Juiz de Fora, Juiz de Fora, Brazil, ²Department of Public Health, Institute of Nursing Science, University of Basel, Basel, Switzerland, ³Transplant Research Group, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, ⁴Nephrology, Hsopital do Rim, Federal University of São Paulo, São Paulo, Brazil, ⁵Pneumology, Federal University of Juiz de Fora, Juiz de Fora, Brazil
*Purpose: Even though regular physical activity is a current recommendation for kidney transplant recipients (KTR), results from ADHERE Brazil study revealed a high prevalence of…
2022 American Transplant Congress
Long-Term (>1 Year) Rejection Free Graft Survival of Kidney Xenografts with Triple Xenoantigen Knockout and Multiple Human Transgenes in Cynomolgus Monkeys
T. Hirose¹, G. Lassiter¹, D. Ma¹, A. D'Attilio¹, I. Rosales¹, D. Cloonan¹, R. Matheson¹, R. Colvin¹, W. Qin², Y. Kan², J. Layer², R. Anand², V. Paragas², L. Queroz², X. Tan², I. Kohnle², K. Stiede², K. Hall², M. Youd², M. Curtis², J. Markmann¹, T. Kawai¹
¹Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, ²eGenesis Inc, Cambridge, MA
*Purpose: Pigs with deletion of 3 carbohydrate xenoantigens (triple knock-out, TKO) are expected to be optimal donors for human xenotransplantation. We have previously shown that…
2022 American Transplant Congress
Clinical Evolution of Patients with De Novo DSA After Kidney Transplantation
C. López del Moral¹, N. Lachmann², S. Hergovits², D. Stauch², A. Akifova³, M. Naik³, B. Osmanodja³, D. Schmidt³, K. Budde³
¹Nephrology department-IDIVAL, Hospital Universitario Marqués de Valdecilla, Santander, Spain, ²Institute for Transfusion Medicine, HLA-Laboratory, Charité - Universitätsmedizin, Berlin, Germany, ³Department of Nephrology and Medical Intensive Care, Charité - Universitätsmedizin, Berlin, Germany
*Purpose: De novo donor-specific antibodies(dnDSA) are related to antibody-mediated rejection(ABMR), but the evolution of patients after dnDSA is variable and not always ABMR and graft…
2022 American Transplant Congress
Donor Kidney-Resident Passenger Macrophages Promote CCL8-CCR8 Mediated Early Allograft Inflammation
A. Dangi¹, I. Husain², N. Natesh³, X. Shen³, J. Kwun⁴, X. Luo⁵
¹Medicine, Duke University Medical Center, Durham, NC, ²Duke University Medical Center, Durham, NC, ³Biomedical Engineering, Duke University, Durham, NC, ⁴Duke Transplant Center, Durham, NC, ⁵Duke University School of Medicine, Durham, NC
*Purpose: Early intragraft infiltration of monocytes and macrophages has been associated with acute and chronic allograft rejections. Nevertheless, underlying mechanism remained poorly understood. In the…
2022 American Transplant Congress
Antibody Response to Sars- Cov -2 Mrna Vaccine in Kidney Transplant Recipients
R. Mohamed Abdul Rahman, M. Alkadi, E. Abuhelaiqa, M. Jarman, A. Nauman, O. Fituri, M. Asim, A. Hamad, H. Tohid, P. Coyle, L. Abu Raddad, H. Al-Malki
Nephrology, Hamad Medical Corporation, Doha, Qatar
*Purpose: Kidney transplant recipients are vulnerable to develop severe form of COVID19 Infection. Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccine has significantly…
2022 American Transplant Congress
Clinical Characteristics Of Serologic Non-responders To Covid-19 Booster Vaccination In A Cohort Of Solid Organ Transplant Recipients.
F. N. Zervou¹, K. Khalil¹, T. Lao¹, D. Wood², S. Jonche¹, A. Mattoo¹
¹Transplant Institute, NYU Langone Health, New York, NY, ²New York University Langone Health, Brooklyn, NY
*Purpose: The purpose of this study was to assess the clinical characteristics of serologic non-responders to COVID-19 booster vaccination in a cohort of solid organ…
2022 American Transplant Congress
Factors Contributing To SARS-CoV-2 Vaccine Hesitancy In Kidney Transplant Candidates
P. LaBella¹, E. Silverman², S. Mehta³, N. M. Ali⁴
¹Transplant Infectious Disease, New York University Langone Health, New York, NY, ²Transplant Infectious Disease, New York University Grossman School of Medicine, New York, NY, ³New York University Langone Transplant Institute, New York, NY, ⁴Transplant Institute, NYU Langone Health, New York, NY
*Purpose: SARS-CoV-2 infection in kidney transplant recipients is associated with an increased risk of severe disease and mortality relative to other patient populations, with mortality…
2022 American Transplant Congress
Sex- and Insurance- Based Disparities in Listing for and Benefit from Simultaneous Heart-Kidney Transplant
B. Wayda¹, X. S. Cheng¹, P. Garcia¹, S. Sanoff², L. M. McElroy², K. K. Khush¹
¹Stanford University School of Medicine, Stanford, CA, ²Duke University School of Medicine, Durham, NC
*Purpose: Rates of simultaneous heart-kidney (SHK) transplant vary widely in the United States (US). Absent uniform eligibility criteria, sex and insurance status could influence patient…