Articles tagged "Kidney transplantation"

2022 American Transplant Congress
Does the New Kidney Transplant Allocation System Impact Delayed Graft Function Rates After Kidney Transplantation?
P. N. Chotai¹, F. Siddiqui², A. Logan³, K. Washburn⁴, A. Schenk⁵, A. Limkemann³
¹Division of Transplantation, Department of General Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, ²Ohio State University, Bloomfield, NJ, ³The Ohio State University Wexner Medical Center, Columbus, OH, ⁴The Ohio State University, Columbus, OH, ⁵Ohio State University Wexner Medical Center, Bexley, OH
*Purpose: The Organ Procurement and Transplantation Network (OPTN) implemented a new, distance based, kidney transplant allocation system (nKAS) for recipients of deceased donor kidney transplant…
2022 American Transplant Congress
Renal Allograft Outcomes of Very High KDPI vs High KDPI Donor Kidneys
R. Rattanavich, R. Villicana
Transplant Nephrology, Transplant Institute Loma Linda University, Loma Linda, CA
*Purpose: Since KDPI > 85 donor kidneys have been commonly used among older recipients, renal allograft outcomes of very high KDPI (≥95) donors have been…
2022 American Transplant Congress
Defects in Kim-1 Do Not Result In Delayed Graft Function After Kidney Transplantation
R. S. Suri¹, J. Lee², M. Ban³, B. Shrum², O. Z. Ismail⁴, S. Leckie⁵, A. McIntyre³, Q. Xu⁶, S. H. Lee², S. de Chickera², R. A. Hegele², L. Gunaratnam²
¹Research Institute of the McGill University Health Center, Montreal, QC, Canada, ²Schulich School of Medicine and Dentistry, Western University, Lodnon, ON, Canada, ³Robarts Research Institute, Lodnon, ON, Canada, ⁴University of Alberta, Edmonton, AB, Canada, ⁵London Health Sciences Centre, Lodnon, ON, Canada, ⁶University of Pittsburg Medical Center, Pittsburg, PA
*Purpose: Tissue repair is critical to restore organ function after ischemia-reperfusion injury (IRI) during transplantation. During renal injury, upregulation of kidney injury molecule-1 (KIM-1) transforms…
2022 American Transplant Congress
Glucose Variability in Kidney Transplantation: Pre-Transplant and Post-Transplant Continuous Glucose Monitoring
E. Jo¹, A. Han², S. Min², J. Ha³, H. Lee⁴, A. Cho⁵
¹Surgery, Seoul National University Hospital, Seoul, Korea, Republic of, ²Seoul National University College of Medicine, Seoul, Korea, Republic of, ³Seoul Nat'l Univ. College of Medicine, Seoul, Korea, Republic of, ⁴Seoul National University Hospital, Seoul, Korea, Republic of, ⁵Surgery, Seoul National University College of Medicine, Seoul, Korea, Republic of
*Purpose: Continuous glucose monitoring (CGM) provides a 24-hour view of glucose values and information on glycemic variability and additional indices such as the glucose management…
2022 American Transplant Congress
Associated Factors to Physical Inactivity of Kidney Transplant Patients: Subproject of ADHERE Brazil Multicenter Study
E. S. Sertorio¹, F. A. Colugnati¹, K. Denhaerynck², S. De Smet³, J. O. Medina⁴, M. M. Reboredo⁵, S. De Geest², H. Sanders-Pinheiro¹, T. ADHERE BRAZIL Study team¹
¹Nephrology, Federal University of Juiz de Fora, Juiz de Fora, Brazil, ²Department of Public Health, Institute of Nursing Science, University of Basel, Basel, Switzerland, ³Transplant Research Group, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, ⁴Nephrology, Hsopital do Rim, Federal University of São Paulo, São Paulo, Brazil, ⁵Pneumology, Federal University of Juiz de Fora, Juiz de Fora, Brazil
*Purpose: Even though regular physical activity is a current recommendation for kidney transplant recipients (KTR), results from ADHERE Brazil study revealed a high prevalence of…
2022 American Transplant Congress
Long-Term (>1 Year) Rejection Free Graft Survival of Kidney Xenografts with Triple Xenoantigen Knockout and Multiple Human Transgenes in Cynomolgus Monkeys
T. Hirose¹, G. Lassiter¹, D. Ma¹, A. D'Attilio¹, I. Rosales¹, D. Cloonan¹, R. Matheson¹, R. Colvin¹, W. Qin², Y. Kan², J. Layer², R. Anand², V. Paragas², L. Queroz², X. Tan², I. Kohnle², K. Stiede², K. Hall², M. Youd², M. Curtis², J. Markmann¹, T. Kawai¹
¹Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, ²eGenesis Inc, Cambridge, MA
*Purpose: Pigs with deletion of 3 carbohydrate xenoantigens (triple knock-out, TKO) are expected to be optimal donors for human xenotransplantation. We have previously shown that…
2022 American Transplant Congress
Clinical Evolution of Patients with De Novo DSA After Kidney Transplantation
C. López del Moral¹, N. Lachmann², S. Hergovits², D. Stauch², A. Akifova³, M. Naik³, B. Osmanodja³, D. Schmidt³, K. Budde³
¹Nephrology department-IDIVAL, Hospital Universitario Marqués de Valdecilla, Santander, Spain, ²Institute for Transfusion Medicine, HLA-Laboratory, Charité - Universitätsmedizin, Berlin, Germany, ³Department of Nephrology and Medical Intensive Care, Charité - Universitätsmedizin, Berlin, Germany
*Purpose: De novo donor-specific antibodies(dnDSA) are related to antibody-mediated rejection(ABMR), but the evolution of patients after dnDSA is variable and not always ABMR and graft…
2022 American Transplant Congress
Donor Kidney-Resident Passenger Macrophages Promote CCL8-CCR8 Mediated Early Allograft Inflammation
A. Dangi¹, I. Husain², N. Natesh³, X. Shen³, J. Kwun⁴, X. Luo⁵
¹Medicine, Duke University Medical Center, Durham, NC, ²Duke University Medical Center, Durham, NC, ³Biomedical Engineering, Duke University, Durham, NC, ⁴Duke Transplant Center, Durham, NC, ⁵Duke University School of Medicine, Durham, NC
*Purpose: Early intragraft infiltration of monocytes and macrophages has been associated with acute and chronic allograft rejections. Nevertheless, underlying mechanism remained poorly understood. In the…
2022 American Transplant Congress
The Cost And Logistical Challenges To Kidney Paired Donation
S. G. Yi¹, V. E. Whittaker², T. B. Dunn³, N. Goldaracena⁴, V. Humphreville⁵, C. Kubal⁶, C. Kuhr⁷, D. Leeser⁸, J. Pomposelli⁹, E. Thomas¹⁰, N. Turgeon¹¹, C. Varma¹², M. Rees¹³, A. K. Mathur¹⁴
¹Houston Methodist Hospital, Houston, TX, ²New York Medical College, Scarsdale, NY, ³University of Pennsylvania, Philadelphia, PA, ⁴Transplant Surgery, University of Virginia Health System, Charlottesville, VA, ⁵University of Minnesota Medical Center, Minneapolis, MN, ⁶Indiana University Hospital, Indianapolis, IN, ⁷Virgina Mason Medical Center, Seattle, WA, ⁸East Carolina Univ Sch of Med, Greenville, NC, ⁹University of Colorado, Aurora, CO, ¹⁰University of Texas Health Science Center at San Antonio, San Antonio, TX, ¹¹Dell Seton Medical Center at The University of Texas, Austin, TX, ¹²St Louis University Hospital, St Louis, MO, ¹³University of Toledo Medical Center, Toledo, OH, ¹⁴Mayo Clinic in Arizona, Phoenix, AZ
*Purpose: Kidney paired donation (KPD) is a strategy for finding compatible pairing for living kidney transplantation (LDKT); however, only a small portion of LDKT continues…
2022 American Transplant Congress
Outcomes in Kidney Transplant Recipients 70 Years and Older
J. Mehta, N. F. Okonkwo, A. Paramesh, K. Atiemo, M. Killackey, H. Jeon, A. Vijay
Tulane University School of Medicine, New Orleans, LA
*Purpose: Patients older than 70 years are the fastest-growing age group of patients requiring renal replacement therapy. This has resulted in a corresponding increase in…