Articles tagged "Kidney transplantation"

2022 American Transplant Congress
Center Variation is the Major Driver of Geographic Disparities in Access to Kidney Transplants Among Waitlisted Candidates
D. Stewart, A. Robinson, A. Wilk, D. Klassen
United Network for Organ Sharing, Richmond, VA
*Purpose: The OPTN’s monitoring of equity in access to deceased donor kidney (KI) transplants (tx) among waitlisted candidates has consistently found service area (DSA) of…
2022 American Transplant Congress
LGALS1 is Expressed in Glomerular Endothelial Cells and Induced Upon Stimulation with Anti-HLA Antibody
A. Boshart¹, S. Farkona¹, S. Clotet-Freixas¹, C. McEvoy¹, J. Murphy¹, S. Crome², A. Konvalinka³
¹Toronto General Hospital Research Institute, Ajmera Transplant Centre, University Health Network, Toronto, ON, Canada, ²Immunology, Toronto General Hospital Research Institute, Ajmera Transplant Centre, University of Toronto, University Health Network, Toronto, ON, Canada, ³Nephrology, Toronto General Hospital Research Institute, Ajmera Transplant Centre, University Health Network, Toronto, ON, Canada
*Purpose: Antibody-mediated rejection (AMR) accounts for >50% of premature kidney graft loss. AMR is caused by donor specific antibodies (DSA) against human leukocyte antigens (HLA)…
2022 American Transplant Congress
Use of Belatacept in Non-Compliant Adolescent Patients
C. McAdams¹, C. Gluck¹, E. Hilmas²
¹Nemours Children's Health, Wilmington, DE, ²Nationwide Children's Hospital, Columbus, OH
*Purpose: Adolescents are at high risk for kidney transplant rejection due to non-compliance. While intravenous (IV) maintenance medications are FDA approved for adults, there is…
2022 American Transplant Congress
Survival Benefit of Early Kidney Transplantation in Infants and Toddlers
S. J. Kizilbash¹, M. Evans², D. Vock², B. Chavers³
¹University of MInnesota, Minneapolis, MN, ²University of Minnesota, Minneapolis, MN, ³Division of Nephrology, Minneapolis, MN
*Purpose: The 1-year mortality in children with end-stage kidney disease (ESKD) has been the highest among infants and toddlers. The objective of this study was…
2022 American Transplant Congress
Impact of Total Parenteral Nutrition on Donor Kidneys During Oxygenated Preservation at 22ºC Ex Vivo
P. Luke¹, A. Jackson², A. Ruthirakanthan², S. Juriasingani², M. Levine¹, L. Jiang², R. Patel², M. Richard-Mohamed¹, S. Forrest¹, A. Sener¹, R. N. Bhattacharjee¹
¹London Health Sciences Centre, London, ON, Canada, ²Western University, London, ON, Canada
*Purpose: Recent studies have shown that ex vivo preservation at 37 º C can reduce kidney injury compared to current clinical practice. However, to mitigate…
2022 American Transplant Congress
Implications of Accumulated Cold Time for US Kidney Transplantation Offer Acceptance
M. Barah¹, V. Kilambi², J. Friedewald¹, S. Mehrotra¹
¹Industrial Engineering and Management Sciences, Northwestern University, Evanston, IL, ²Department of Engineering and Applied Sciences, RAND Corporation, Arlington, VA
*Purpose: Reducing discard is a current focus in US transplantation of deceased donor kidneys. One cause for the discards is the avoidance of protracted cold…
2022 American Transplant Congress
Cardiovascular Assessment After Kidney Transplantation in Children and Adolescents
J. Liu, L. Zhang, X. Li, L. Zhu, Y. Lin, X. He, L. Liu, J. Li, C. Wang, S. Li
The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
*Purpose: End-stage renal disease is often accompanied by cardiovascular events, and cardiovascular events still exist after kidney transplantation. Cardiovascular disease is the main cause of…
2022 American Transplant Congress
Living Donor Kidney Transplant in Recipients with Glomerulonephritis: Donor Recipient Biologic Relationship and Allograft Outcomes
R. El-Rifai¹, R. Spong¹, A. Bregman¹, K. Swanson¹, S. Jackson², S. Riad¹
¹Nephrology, University of Minnesota, Minneapolis, MN, ²MHealth, Minneapolis, MN
*Purpose: Controversies exist over the impact of donor-recipient biologic relationship on the outcomes of living donor kidney transplant in recipients with glomerulonephritis (GN). The improved…
2022 American Transplant Congress
Impact of a Pharmacy-Led Post-Transplant Diabetes Mellitus Clinic in Solid Organ Transplant Recipients
H. Sweiss¹, R. Hall¹, M. Flores², S. Bhayana¹, R. Patel¹, C. Long²
¹University Health - University Hospital, San Antonio, TX, ²College of Pharmacy, University of Incarnate Word, San Antonio, TX
*Purpose: To evaluate the impact of a pharmacy-led post-transplant diabetes mellitus (DM) clinic.*Methods: This retrospective chart review from 08/01/20 to 6/30/21 evaluated adult kidney transplant…
2022 American Transplant Congress
Sirolimus Use Is Associated With An Improved Immune Response To Covid-19 Vaccination In Kidney Transplant Recipients
G. B. Perkins¹, M. Tunbridge², T. Salehi², C. Chai¹, C. M. Hope¹, P. Garcia-Valtanen¹, J. J. Singer³, P. R. Hurtado², S. C. Barry¹, B. Grubor-Bauk¹, P. Hissaria², S. J. Chadban³, P. Coates¹
¹University of Adelaide, Adelaide, Australia, ²Royal Adelaide Hospital, Adelaide, Australia, ³Royal Prince Alfred Hospital, Sydney, Australia
*Purpose: Kidney transplant recipients (KTRs) are highly vulnerable to severe COVID-19, however are poorly protected by vaccination. Additional vaccine doses have achieved limited improvements in…