ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2015 American Transplant Congress

    Clusterin-Regulated Transcriptome in the Kidney During Ischemia-Reperfusion

    G. Dairi, Q. Guan, A. Haegert, C. Collins, M. Gleave, C. Nguan, C. Du.

    Department of Urological Sciences, Vancouver, Canada; The University of British Columbia, Vancouver, Canada; Immunity and Infection Research Centre, Vancouver, Canada; Vancouver Coastal Health Research Institute, Vancouver, Canada.

    BACKGROUND: Ischemia-reperfusion injury (IRI) has a significate impact on both short and long-term transplant outcomes, and is a major cause of delayed graft function in…
  • 2015 American Transplant Congress

    Treatment With Everolimus and Reduced-Exposure Cyclosporine Is Efficacious in De Novo Renal Transplant Recipients at Increased Risk for Efficacy Failure: Post-Hoc Analysis from the A2309 Study

    M. Carmellini,1 V. Garcia,1 Z. Wong,2 M. Vergara,2 C. Escrig,2 G. Russ.1

    1For the A2309 Study Group, Italy; 2Novartis, Basel, Switzerland.

    Purpose: Data is limited on the effect of everolimus (EVR) based regimens in renal transplant recipients (RTxR) who are at increased risk for rejection and…
  • 2015 American Transplant Congress

    Calcineurin Inhibitor-Free Immunossupresion After Kidney Transplantation, Using Everolimus De Novo – Single Center Experience

    M. Stronka, Z. Adamska, L. Cichanska, J. Kubiak, M. Gamrat, M. Karczewski.

    Department of Transplantology, General, Vascular and Plastic Surgery, Clinical Hospital of Poznan University of Medical Sciences, Poznan, Poland.

    The aim of the study was to analyse the clinical outcome in kidney transplant recipients treated with CNI (calcineurin inhibitors)-free protocol versus kidney transplant recipients…
  • 2015 American Transplant Congress

    Long-Term Follow-Up After Conversion from Twice-Daily Tacrolimus Formulation to Once-Daily Tacrolimus Formulation in Pediatric Kidney Transplantation

    C. Choi, A. Han, S. Min, S.-K. Min, T. Lee, I.-M. Jung, S. Kim, J. Ha.

    Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea.

    PurposeTacrolimus is one of the most frequently used immunosuppressants in pediatric kidney transplantation (KT) as in adult. In Pediatric kidney recipients, it is more important…
  • 2015 American Transplant Congress

    Program-Effect Attenuation With Time Posttransplant

    N. Salkowski,1 L. Hunsicker,1,2 J. Snyder,1 B. Kasiske.1,3

    1Scientific Registry of Transplant Recipients, Minneapolis Medical Research Foundation, Minneapolis, MN; 2Department of Medicine, University of Iowa, College of Medicine, Iowa City, IA; 3Department of Medicine, University of Minnesota, Minneapolis, MN.

    The program-specific reports produced by SRTR include 1-month, 1-year, and 3-year posttransplant graft and patient survival measures. The 1-month and 1-year measures use the same…
  • 2015 American Transplant Congress

    Clinical Subclassifiation of ABMR Phenotypes: Recognizing Variation in Presentation

    P. Halloran, M. Lopez, I. Salazar, J. Chang.

    Alberta Transplant Applied Genomics Centre, Edmonton, Canada.

    The diagnosis of ABMR in kidney transplants is based on ptc-, g- and cg-lesions in biopsies and donor-specific antibody (DSA). To recognize the actual phenotypes…
  • 2015 American Transplant Congress

    The Economic Impact of Nonimmune Complications in Contemporary Kidney Transplantation

    K. Lentine,1 M. Schnitzler,1 D. Axelrod,2 D. Segev,3 D. Brennan,4 J. Tuttle-Newhall,1 H. Xiao,1 L. Kucirka,3 V. Dharnidharka.4

    1Saint Louis Univ, St Louis; 2Dartmouth, Lebanon; 3Johns Hopkins, Baltimore; 4Washington Univ, St. Louis.

    The clinical burden and economic impacts of nonimmune complications after kidney transplant (KT) are incompletely defined.We examined United States Renal System Registry Data for Medicare-insured…
  • 2015 American Transplant Congress

    Assessment of IgG Subclass Significance for Early Graft Rejection and Long-Term Survival in HLA-Antibody Incompatible Renal Transplantation: Multivariate Approach

    N. Khovanova,1 D. Lowe,2 S. Daga,1,3 T. Shaikhina,1 N. Krishnan,3 D. Mitchell,1 D. Zehnder,1 D. Briggs,2 R. Higgins.3

    1University of Warwick, Coventry, United Kingdom; 2NHS Blood and Transplant, Birmingham, United Kingdom; 3University Hospitals Coventry and Warwickshire, Coventry, United Kingdom.

    Donor HLA specific antibodies (DSA) can cause acute rejection and graft lost after renal transplantation. However neither the damaging antibody types, nor their acceptable levels…
  • 2015 American Transplant Congress

    Loss of RIPK3 and Caspase-8 Enhance Intrinsic Apoptosis in Tubular Epithelial Cell (TEC) Death and Contributes to Kidney Ischemia Reperfusion Injury (IRI)

    B. Sung,1 Y. Su,3 A. Lau,3 J. Jiang,3 A. Haig,2 D. Green,4 Z. Zhang,2 A. Jevnikar.1

    1Microbiology and Immunology, Western University, London, ON, Canada; 2Pathology, Western University, London, ON, Canada; 3Matthew Mailing Centre for Translational Transplant Studies, London Health Sciences Centre, London, ON, Canada; 4St. Jude Children's Research Hospital, Memphis, TN.

    [Background] Ischemia-reperfusion injury (IRI), a complex limiting factor in organ transplant survival, is related to multiple death pathways. Eliminating the key necroptotic molecule (RIPK3) improves…
  • 2015 American Transplant Congress

    Reduced Incidence of Cytomegalovirus Infection in Kidney Transplant Recipients Receiving Everolimus

    H. Tedesco-Silva,1 C. Felipe,1 A. Ferreira,1 M. Cristelli,1 T. Sandes- Freitas,1 N. Oliveira,1 W. Aguiar,2 G. Bassos,1 M. Franco,3 M. Gerbase- Lima,4 E. Campos,4 J. Medina-Pestana.1

    1Nephrology, Hospital do Rim UNIFESP, Sao Paulo, Brazil; 2Urology, Hospital do Rim UNIFESP, Sao Paulo, Brazil; 3Pathology, UNIFESP, Sao Paulo, Brazil; 4Immunogenetic, AFIP, Sao Paulo, Brazil.

    BACKGROUND: CMV infection is associated with inferior long-term kidney transplant outcomes. This study compared the incidence of CMV infection/disease in de novo kidney transplant recipients…
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