ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2022 American Transplant Congress

    Efficacy and Safety of PCSK-9 Inhibitor, Evolocumab for Lipid Management in Kidney Transplant Recipients

    J. Pandav1, R. Saranu1, S. Muhsin1, N. Murakami1, S. Gabardi1, K. Safa2, A. Chandraker1

    1Renal division, Brigham and Women's Hospital, Boston, MA, 2Renal division, Massachusetts General Hospital, Boston, MA

    *Purpose: Dyslipidemia is common in kidney transplant recipients (KTRs). KDIGO guidelines suggest all KTRs should be treated with statins due to the high risk of…
  • 2022 American Transplant Congress

    Inferior Kidney Transplant Outcomes in Young Adults Transplanted as Children

    K. Deville, F. Rosenblum, D. R. Kelly, M. Seifert

    UAB School of Medicine, Birmingham, AL

    *Purpose: Adolescence (age 13-17 years) has been identified as a high-risk age interval for pediatric kidney transplant recipients, with accelerated rates of late acute rejection…
  • 2022 American Transplant Congress

    Long Term Analysis of Pediatric En-Bloc Kidney Transplantation: A Single Center Experience

    H. H. Patel1, P. Di Cocco2, J. Almario2, A. Fratti2, S. Akshelyan2, E. Benedetti2, I. Tzvetanov2, M. Spaggiari2

    1University of Missouri-Kansas City School of Medicine, Kansas City, MO, 2University of Illinois at Chicago, Chicago, IL

    *Purpose: Pediatric en-bloc kidney transplantations for adult recipients are uncommonly performed due to unique donor characteristics, the technical challenge of the operation, and potential surgical…
  • 2022 American Transplant Congress

    BiomarkeR Initiative to Advance Transplantation OutcomEs in Children (BRITE-c) Analysis

    M. E. Seifert1, L. Sheward2, A. Kho2, N. Rodig2, V. Dharnidharka3, M. Diehl2, R. B. Mannon4, O. Bestard5, T. Blydt-Hansen6, D. M. Briscoe2

    1University of Alabama, Birmingham, AL, 2Boston Children's Hospital, Boston, MA, 3St Louis Children's Hospital, St Louis, MO, 4University of Nebraska, Omaha, NE, 5Bellvitge University Hospital, Barcelona, Spain, 6BC Childrens, Vancouver, BC, Canada

    *Purpose: Recent studies indicate that 25-36% of clinically stable pediatric renal transplant recipients will have subclinical rejection detected on surveillance biopsy. These findings highlight a…
  • 2022 American Transplant Congress

    Barriers and Facilitators to Care for Patients with Failed Kidney Transplants

    A. Huml1, K. Berg2, A. Perzynski2, C. Sullivan2, A. Sehgal2

    1Department of Kidney Medicine, Cleveland Clinic, Cleveland, OH, 2Population Health Research Institute, The MetroHealth System, Cleveland, OH

    *Purpose: To understand the barriers and facilitators to care for patients with failed kidney transplants from the perspective of providers.*Methods: Qualitative study employed focus groups…
  • 2022 American Transplant Congress

    First-in-Human Clinical-Grade Porcine Kidney Xenotransplant

    J. E. Locke1, B. Orandi1, V. Kumar1, J. Houp1, D. Anderson1, V. Hauptfeld1, D. Martin2, C. Killian1, S. Macedon1, N. Budd1, K. Stegner1, A. Dandro3, M. Kokkinaki3, K. Kuravi3, R. Reed4, H. Fatima1, G. Baker1, J. Perry1, E. Bryant1, M. Cheung1, E. Erman1, K. Kraebber1, T. Gamblin1, L. Guy1, D. Ayares3, P. Porrett1

    1University of Alabama at Birmingham, Birmingham, AL, 2Deakin University, Geelong, Australia, 3Revivicor, Incorporated, Blacksburg, VA, 4University of Alabama at Birmingham, Irondale, AL

    *Purpose: Proof-of-concept xenotransplant work has been performed in pig to non-human primates (NHP), but it is unclear if outcomes can be recapitulated in humans. While…
  • 2022 American Transplant Congress

    Which is More Important for Predicting De Novo DSA Production, B Cell Epitope (EPLET) or T Cell Epitope (PIRCHE) Analysis ?

    T. Kobayashi1, T. Tomosugi2, S. Sakamoto2, S. Ashimine1, K. Iwasaki1, M. Niemann3, E. Spierings4, Y. Miwa1, M. Okumura1, K. Ishiyama1, A. Takeda2, N. Goto2, S. Narumi2, Y. Watarai2

    1Aichi Medical University School of Medicine, Nagakute, Japan, 2Nagoya Daini Red Cross Hospital, Nagoya, Japan, 3PIRCHE AG, Berlin, Germany, 4UMC Utrecht, Utrecht, Netherlands

    *Purpose: De novo donor-specific antibodies (dnDSA) can cause chronic ABMR, resulting in poor prognosis. Recently, mismatch at B cell epitope level, i.e. EPLET mismatch, has…
  • 2022 American Transplant Congress

    Preoperative Antibiotics Administration is Important to Prevent Hand Port-Site Infection After Hand-Assisted Laparoscopic Donor Nephrectomy for Living-Donor Kidney Transplantation

    T. Hiramitsu, T. Tomosugi, K. Futamura, M. Okada, N. Goto, T. Ichimori, S. Narumi, Y. Watarai

    Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital, Nagoya, Japan

    *Purpose: Due to the profound organ shortage, the number of living donor kidney transplantation (LDKT) is increasing. Hand-assisted laparoscopic donor nephrectomy (HALDN) is widely performed…
  • 2022 American Transplant Congress

    Landscape of Attitudes Towards Living Kidney Donation During the SARS-CoV-2 Pandemic in the United States: Results of a Public Opinion Survey

    K. Kaplow1, J. Ruck1, A. Thomas1, D. Warren1, D. Segev1, C. Corlett2, J. Sinacore3, M. Levan1

    1Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, 2Brand Planning LLC, Williamsburg, VA, 3National Kidney Registry, Babylon, NY

    *Purpose: Solid organ transplantation decreased during the SARS-CoV-2 pandemic largely due to temporary shutdowns. The pandemic revealed significant gaps in medical knowledge among the public;…
  • 2022 American Transplant Congress

    HLA-DRB1 and DQB1 Amino Acid Mismatches as Determinants of Kidney Allograft Failure

    L. Gragert1, K. P. McCullough2, G. L. Wager3, R. Urbanowicz4, R. M. Merion2, M. Kamoun4

    1Tulane Cancer Center, Tulane University, New Orleans, LA, 2Arbor Research Collaborative for Health, Ann Arbor, MI, 3Tulane University, New Orleans, LA, 4University of Pennsylvania, Philadelphia, PA

    *Purpose: It was previously reported that HLA-DRB1 amino acid (AA) mismatches (MMs) at peptide-binding pockets of this molecule account for significant incremental risk of kidney…
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