2015 American Transplant Congress
Noninvasive Diagnostic and Predictive Value in Renal Transplant Recipients by Measurement of Urine BCA-1
ObjectiveTo investigate the relationship between early-stage renal acute rejection and the level of BCA-1 in urine, explore the diagnostic value and noninvasive monitoring in early…2015 American Transplant Congress
Enhanced Production of Macrophage Chemoattractant Protein-1 (MCP-1) Within the Kidney in Brain Death Donors Predicts Recipient Allograft Function
Medicine/Surgery, University of Alabama at Birmingham, Birmingham, AL.
Brain death (BD) induces an intense pro-inflammatory state, which may impact recipient immunity and graft function after kidney transplantation. The identification of biomarkers predictive of…2015 American Transplant Congress
The Effects of High-Risk Donors and Recipients on Scientific Registry of Transplant Recipients Program-Specific Outcomes
Public reporting of transplant program-specific outcomes may dissuade programs from accepting high-risk donors and recipients, and thereby restrict access to transplant. It has been proposed…2015 American Transplant Congress
Investigation of Myocardial Function in Pediatric Transplant Recipients
Children's National, Washington, DC.
Purpose: In light of the major impact of cardiovascular morbidity on long-term transplant outcomes, a prospective controlled study was conducted to investigate changes in myocardial…2015 American Transplant Congress
Urinary CXCL10 Independently Improves the Noninvasive Diagnosis of Antibody-Mediated Kidney Allograft Rejection
The urinary levels of CXCL9 and CXCL10 can noninvasively diagnose T cell-mediated rejection (TCMR) of renal allografts. Their performance as diagnostic/prognostic markers of antibody-mediated rejection…2015 American Transplant Congress
Patient and Process-Level Factors Associated With Kidney Transplant Readmissions
Readmissions following kidney transplantation (KTX) are common, with complex etiologies. There is a lack of research exploring the potential of optimizing post-transplant processes to reduce…2015 American Transplant Congress
The Effect of Rituximab Therapy on Regulatory B Cell and Prevention of Chronic Antibody Mediated Rejection in Kidney Transplantation Recipients
Urology, Tokyo Women's Medical University, Tokyo, Japan.
We previously reported that a single administration of low dose rituximab (RIT) before kidney transplant reduced the incidence rate of chronic antibody mediated rejection (CAMR)…2015 American Transplant Congress
Risk Associated With DCD Kidney Transplantation Varies by Donor Characteristics
Studies have shown that comparable kidney graft survival between donors after brain death (DBD) and donors after circulatory death (DCD) overall. However, the differential risk…2015 American Transplant Congress
Erythropoietin (EPO) Has Treg Sparing Immunosuppressive Effects On Human Alloreactive T Cells
Translational Transplant Research Center, Icahn School of Medicine at Mount Sinai, New York, NY.
Extending previous work showing that EPO inhibits alloreactive effector T cell proliferation by uncoupling IL2 receptor signaling (JASN 2014), we tested the effects of EPO…2015 American Transplant Congress
Morphometric Age as a Predictor of Survival Following Kidney Transplantation
1University of Michigan, Ann Arbor, MI; 2Case Western Reserve University, Cleveland, OH.
INTRODUCTION: Better measures of pre-operative risk stratification are needed in kidney transplantation. Analytic morphomics, which utilizes pre-operative imaging, has been shown to objectively assess mortality…
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