Articles tagged "Kidney transplantation"

2015 American Transplant Congress
Histopathological Criteria for Elevated Risk of Delayed Graft Function in German Pretransplantation Kidney Biopsies from Deceased Donors
J. Becker,¹ B. Eggers,² P. Mertens,³ A. Schwarz,⁴ C. Chatzikyrkou.³
¹Institute of Pathology, University Hospital of Cologne, Cologne, North Rhine-Westfalia, Germany; ²Deutsche Stiftung Organtransplantation, Frankfurt, Hesse, Germany; ³Department of Nephrology and Hypertension, Diabetology and Endocrinology, University Hospital of Magdeburg, Magdeburg, Saxonia-Anhalt, Germany; ⁴Clinic for Nephrology and Hypertension, Hannover Medical School, Hannover, Lower Saxony, Germany.
Introduction:Delayed graft function (DGF) is more frequent with so called marginal kidney donors. Moreover, it is linked to increased recipient mortality and inferior transplant outcome.…
2015 American Transplant Congress
Kidney Transplant Outcomes in Marijuana Users
P. Shrivastava,¹ A. Naik,¹ A. Sakhuja,¹ Y. Lu,¹ Y. Huang,¹ F. Barrantes,² F. Luan,³ S. Kulshrestha,⁴ M. Samaniego.¹
¹Dept of Internal Medicine, University of Michigan, Ann Arbor, MI; ²Presbyterian Kidney Transplantation, Albuquerque, NM; ³Dept of Kidney and Pancreas Transplantation, St. Barnabas Medical Center, Livingston, NJ; ⁴Dept of Internal Medicine, University of Iowa, Iowa City, IA.
Introduction: As Marijuana use is gaining social acceptance, many transplant centers face questions regarding candidacy of users for kidney transplantation. Currently its impact on post-transplantation…
2015 American Transplant Congress
Birth Weight as a Marker of Nephron Mass: Impact on Renal Allograft Function
T. Schachtner,^1,2 P. Reinke.^1,2
¹Nephrology and Internal Intensive Care, Charité Campus Virchow Clinic, Berlin, Germany; ²Berlin-Brandenburg Center for Regenerative Therapies, Berlin, Germany.
Nephron number has been considered a major determinant of renal allograft function and outcome. It has been demonstrated that low birth weights give rise to…
2015 American Transplant Congress
Expanding the Living Donor Pool: Results of ABO Incompatible Living Related Kidney Transplantation
T. Vowinkel,¹ S. Reuter,² C. Anthoni,¹ N. Senninger,¹ B. Suwelack,² H. Wolters.¹
¹Department of General and Visceral Surgery, University Hospital Muenster, Muenster, Germany; ²Department of Medicine D, University Hospital Muenster, Muenster, Germany.
Background: Organ shortage has led to an increase in living related kidney transplantation. Here we report on our program of expanding the living donor pool…
2015 American Transplant Congress
Investigating Role of Early VTE Chemoprophylaxis in Kidney Transplant
D. Kendrick,¹ E. Kudlaty,¹ A. Kim,¹ P. Moorehead,¹ J. Augustine,² E. Sanchez,² V. Kashyap,¹ K. Woodside.²
¹Vascular Surgery, University Hospitals-Case Medical Center, Cleveland, OH; ²Transplant Institute, University Hospitals-Case Medical Center, Cleveland, OH.
Objective: Our objective was to determine whether the rate of venothromboembolic events (VTE) varied with early versus delayed prophylaxis administration. Associated bleeding complications were also…
2015 American Transplant Congress
Increased Vascular Stiffness in Pediatric Renal Transplant Recipients Despite Normal Kidney Function, Blood Pressure, and Body Mass Index
M. Seifert,^1,2 N. Kulsum-Mecci,² L. de las Fuentes,² V. Davila-Roman,² K. Hruska.²
¹Southern Illinois University, Springfield, IL; ²Washington University, St. Louis, MO.
Background: Chronic kidney disease (CKD) imparts enormous cardiovascular (CV) risk that is only partially improved by renal transplantation. We sought to understand the determinants of…
2015 American Transplant Congress
Serum Osteoprotegerin Levels Positively Correlate With Peripheral Arterial Stiffness in Kidney Transplantation Patients
M.-C. Lee,^1,2 G.-J. Ho,¹ Y.-C. Chen,¹ B.-G. Hsu.²
¹Department of Surgery, Tzu Chi General Hospital, Hualien, Taiwan; ²Department of Medicine, School of Medicine Tzu Chi University, Hualien, Taiwan; ³Department of Medicine, Tzu Chi General Hospital, Hualien, Taiwan.
Objective: Recent studies found osteoprotegerin (OPG) is associated with increased pulse wave velocity and may reflect endothelial dysfunction. The aim of this study was to…
2015 American Transplant Congress
The Value of Surveillance Testing for De Novo Donor Specific Antibodies Following Renal Transplantation
O. Pankewycz,¹ M. Laftavi,² M. Said,² K. Chapin,² L. Feng.²
¹Medicine, SUNY at Buffalo/ECMC, Buffalo, NY; ²Surgery, SUNY at Buffalo/ECMC, Buffalo, NY.
The development of de novo donor specific antibodies (dnDSA) usually leads to a reduction in renal graft survival. The deleterious influence of dnDSA is most…
2015 American Transplant Congress
NK Cells of Kidney Transplant Recipients Show a Reduced Capacity to Produce Cytokines But Retain Their Cytotoxic Capacity
U. Hoffmann,¹ C. Neudoerfl,¹ K. Daemen,¹ J. Keil,¹ C. Blume,^2,3 F. Lehner,⁴ H. Haller,² C. Falk.^1,5
¹Inst. of Transplant Immunology, IFB-Tx, Hanover Medical School, Hanover, Germany; ²Dept. of Nephrology and Hypertension, Hanover Medical School, Hanover, Germany; ³Inst. of Technical Chemistry, Leibniz University Hanover, Hanover, Germany; ⁴Dept. of General, Visceral, and Transplantation Surgery, Hanover Medical School, Hanover, Germany; ⁵German Center for Infection Research, Braunschweig, Germany.
The role of NK cells in either graft rejection or tolerance induction is still discussed controversially. In order to clarify the effect of long-term immunosuppression…
2015 American Transplant Congress
Superior Renal Function in an Everolimus-Based Calcineurin Inhibitor Free Regimen Compared to Standard Cyclosporine/Mycophenolate and Low Cyclosporine/Everolimus: Follow-Up of the HERAKLES Study at Month 48
K. Budde,¹ C. Sommerer,¹ P. Weithofer,¹ O. Witzke,¹ M. Guba,¹ J. Jacobi,¹ B. Vogt,³ I. Hauser,¹ R. Stahl,¹ P. Reinke,¹ T. Rath,¹ D. Baeumer,² M. Porstner,² M. Zeier,¹ F. Lehner,¹ W. Arns.¹
¹Herakles Study Group, Germany; ²Novartis, Pharma, Germany; ³Herakles Study Group, Switzerland.
Aim: To follow up on renal function (GFR) at month (Mo) 48 after kidney transplantation (Tx) in patients (pts) on immunosuppressive regimen with different calcineurin…