Articles tagged "Kidney transplantation"

2015 American Transplant Congress
Kidney Donor Profile Index Variability in Donors With Dialysis Dependent Acute Kidney Injury and the Impact On Organ Allocation
A. Pai,¹ M. Ghanta,¹ S. Rao,¹ A. Gillespie,¹ S. Karhadkar,² K. Lau,² A. Di Carlo,² S. Constantinescu,¹ I. Lee.¹
¹Nephrology, Temple Univesity School of Medicine, Philadelphia, PA; ²Surgery, Temple Univesity School of Medicine, Philadelphia, PA.
Kidney Donor Profile Index (KDPI) is calculated using 10 donor variables including terminal serum creatinine (Cr) and is used in the new kidney allocation system…
2015 American Transplant Congress
Prospective, 6 Month, Open Label, Conversion Study from Mycophenolate Mofetyl to Mycophenolic Acid Evaluating the Severity of Gastro-Intestinal Symptoms and Mycophenolic Acid Urinary Metabolite as a Surrogate Marker of Plasmatic Area Under the Curve
D. Tran,¹ A. Boucher,¹ L. Senécal,¹ V. Pichette,¹ F. Leblond,² S. Collette.¹
¹Nephrology, Hôpital Maisonneuve-Rosemont, Montréal, QC, Canada; ²Research Center, Hôpital Maisonneuve-Rosemont, Montréal, QC, Canada.
Introduction: Treatment with mycophenolate mofetil (MMF) often results in adverse gastro-intestinal (GI) events, which can lead to dose reductions that in turn can increase the…
2015 American Transplant Congress
Desensitization Before Living Donor Kidney Transplantation in Highly Sensitized Patients
E. De Sousa,¹ I. Revuelta,¹ M. Blasco,¹ F. Diekmann,¹ J. Cid,² M. Lozano,² A. Sánchez-Escuredo,¹ J. Martorell,³ E. Palou,³ J. Campistol,¹ F. Oppenheimer.¹
¹Nephrology, Hospital Clinic Barcelona, Barcelona, Spain; ²Hemotherapy and Hemostasis, Hospital Clinic Barcelona, Barcelona, Spain; ³Immunology, Hospital Clinic Barcelona, Barcelona, Spain.
Renal transplantation in highly sensitized patients represents a major clinical challenge leading to long periods in the waiting list. When a living donor is available,…
2015 American Transplant Congress
Addressing Low Live Kidney Donation Rates in African Americans through the Live Donor Champion Program
E. King,¹ J. Garonzik-Wang,³ M. Bowring,¹ K. Kumar,¹ D. Segev.^1,2
¹Surgery, Johns Hopkins University, School of Medicine, Baltimore, MD; ²Epidemiology, Johns Hopkins University, School of Public Health, Baltimore, MD; ³Transplantation, Washington University, School of Medicine, St. Louis, MO.
Background: African-Americans (AAs) are least likely to receive a live donor kidney transplant, and AAs account for < 20% of all live donors. Differences in…
2015 American Transplant Congress
Renal Vein Elongation in Deceased Right Side Cadaveric Renal Grafts: Does It Increase the Risk of Thrombosis Or Hematoma Formation?
J. Neves Neto, R. Soler, H. Marinho Neto, A. Ferreira, Jr., J. Offerni, S. Ximenes, J. Medina-Pestana, V. Ortiz, W. Aguiar, B. Leslie.
Urology, Federal University of Sao Paulo, Sao Paulo, Brazil.
INTRODUCTION:There is a perceived feeling that elongation of the renal vein in right sided kidney grafts facilitates the vascular anastomosis. On the other hand some…
2015 American Transplant Congress
Frequencies of CD4⁺25^hiFoxp3⁺T Cells in Long-Term Follow-Up of Sirolimus-Converted Kidney Transplant Recipients
O. Traitanon,^1,2 A. Alvarado,¹ E. Tantisattamo,^1,2 A. Shetty,^1,2 M. Ansari,^1,2 J. Mathew,¹ J. Leventhal,¹ V. Mas,³ L. Gallon.^1,2
¹Comprehensive Transplant Center, Northwestern University, Chicago, IL; ²Medicine-Nephrology, Northwestern University, Chicago, IL; ³Surgery, University of Virginia, Charlottesville, VA.
Background: Tacrolimus(TAC) and Sirolimus(SRL) are commonly used immunosuppressive drugs in kidney transplantation. SRL has been shown to induce the expansion of regulatory T cells in…
2015 American Transplant Congress
Characterization of Peripheral Blood T and B Cells of Sensitized Kidney Transplant Recipients With Long Term Stable Graft Function
N. Galante,¹ M. Fernandes,¹ F. Agena,¹ A. Triboni,¹ G. Freitas,¹ A. Aguirre,¹ W. Nahas,¹ V. Coelho,² E. David-Neto.¹
¹Renal Transplant Service, Hospital das Clínicas - University of Sao Paulo School of Medicine, Sao Paulo, Brazil; ²Laboratory of Immunology, Heart Institute - University of Sao Paulo School of Medicine, Sao Paulo, Brazil.
We examined the phenotype of T and B cells of peripheral blood of sensitized kidney transplant recipients with stable graft function (GFR > 29mL/min) enrolled…
2015 American Transplant Congress
Cultural Domains Affecting Organ Donation in Indian Country
T. Bongiovanni,^1,3,4 J. Rawlings,² J. Trompeta,³ M. Nunez-Smith.¹
¹Dept of Surgery, UCSF, San Francisco; ²Tribal Council, New Haven, CT; ³Robert Wood Johnson Foundation, Yale School of Medicine, New Haven, CT; ⁴Department of Veterans Affairs, West Haven.
Background: The prevalence of end-stage renal disease is 3.5 times greater among the >2.5 million Native Americans or Alaskan Natives (NAs) in the US than…
2015 American Transplant Congress
Phenotype of Renal Tubular Cell Death During Delayed Graft Function
S. Jain,¹ R. Plenter,¹ T. Nydam,¹ C. Ruller,¹ C. Edelstein,^1,2 A. Jani.^1,2
¹University of Colorado, Aurora, CO; ²Veterans Affairs Medical Center, Denver, CO.
Background: Delayed graft function (DGF) independently predicts reduced 5 yr kidney transplant survival. Treatments of DGF are lacking. Cold ischemia (CI) is a significant risk…
2015 American Transplant Congress
Factors Affecting Efficacy Outcomes at 12 and 24-Months After Kidney Transplantation in Patients from the A2309 Study
C. Escrig,¹ G. Colussi,² R. Roland,² M. Vergara,³ Z. Wang.³
¹Novartis, Basel, Switzerland; ²A2309 Study Group, Basel, Switzerland; ³Novartis, East Hanover, NJ.
Purpose: Efficacy outcomes post-transplantation are influenced by donor and recipient variables and interactions between them. Here, we present data from a multivariate analysis of risk…