Articles tagged "Kidney transplantation"

2015 American Transplant Congress
Impact of Induction Therapy on Outcomes in HIV + Renal Transplant Recipients
C. Kershaw,¹ C. Rogers,^2,4 M. Pavlakis,^1,2 H. Tang,² C. Alonso,^1,2 K. Khwaja,^2,3 A. Evenson,^2,3 K. Raven,^2,3 M. Wong.^1,2
¹Medicine, Beth Israel Deaconess Medical Center (BIDMC), Boston, MA; ²The Transplant Institute, BIDMC, Boston, MA; ³Surgery, BIDMC, Boston, MA; ⁴Pharmacy, BIDMC, Boston, MA.
Purpose: Kidney transplantation in HIV+ recipients has been complicated by higher than expected acute rejection rates (AR). Induction immunosuppression may or may not impact this…
2015 American Transplant Congress
Impact of Cold Ischemic Time (CIT) and Distance Traveled (DT) on Shipped Kidneys in the OPTN/UNOS Kidney Paired Donation (KPD) Pilot Program (PP)
M. Aeder,¹ D. Stewart,² R. Leishman,² L. Robbins Callahan,² A. Kucheryavaya,² T. Sandholm,³ R. Formica.⁴
¹Univ Hosp Case Med Ctr, Cleveland, OH; ²UNOS, Richmond, VA; ³Carnegie Mellon Univ, Pittsburgh, PA; ⁴Yale Univ, New Haven, CT.
Background: The success of a national KPD program is predicated on excellent early kidney function and graft survival (GS). As other KPD programs have reported…
2015 American Transplant Congress
Characteristics and Outcomes of Renal Transplant Recipients With Hemolytic Uremic Syndrome: An OPTN Registry Analysis
B. Tanriover,¹ M. MacConmara,² R. Saxena,¹ Y.-M. Shen.³
¹Medicine/Nephrology, UT Southwestern, Dallas, TX; ²Surgery, UT Southwestern, Dallas, TX; ³Medicine/Hematology, UT Southwestern, Dallas, TX.
Hemolytic uremic syndrome (HUS) accounts for <1% of renal transplants in the US. There is limited data on the characteristics and outcomes of in pediatric…
2015 American Transplant Congress
Chimeric Thymus Versus Antigen Presenting Thymus for the Induction of Tolerance: Donor DCs in Vascularized Thymus Grafts Play an Essential Role in the Induction of Tolerance
K. Yamada, M. Sekijima, A. Kawai, T. Tanabe, M. Tasaki, V. Villani, I. Hanekamp, A. Shimizu, D. Sachs.
Transplantation Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
We have demonstrated that thymus plays an important role in transplantation tolerance in MHC inbred large animals. We have established a technique of isolated vascularized…
2015 American Transplant Congress
Impact of Integrase Inhibitor-Based Antiretroviral Regimen on Outcomes in HIV + Renal Transplant Recipients
C. Kershaw, C. Rogers, M. Pavlakis, H. Tang, C. Alonso, K. Khwaja, A. Evenson, K. Raven, M. Wong.
Beth Israel Deaconess Medical Center, Boston.
Renal transplant in HIV+ patients (pts) is complicated by high rates of acute rejection (AR). Protease inhibitors (PIs) and non-nucleoside reverse transcriptase inhibitors (NNRTIs) have…
2015 American Transplant Congress
Outcomes of Live Kidney Donors Who Develop End Stage Renal Disease
A. Muzaale, A. Massie, L. Kucirka, D. Segev.
Johns Hopkins, Baltimore.
Kidney donors can develop ESRD after donation, but the outcomes of those who do remain poorly characterized.Methods: Using USRDS and SRTR data, we compared access…
2015 American Transplant Congress
ASKP1240 in De Novo Kidney Transplant Recipients
R. Harland,¹ G. Klintmalm,² H. Yang,³ S. Jensik,⁴ T. Shah,⁵ P. West-Thielke,⁶ F. Shihab,⁷ W. Zhang,⁸ V. Santos,⁸ R. Tainaka,⁸ X. Wang,⁸ R. First,⁸ J. Holman.⁸
¹East Carolina University, Greenville, NC; ²Baylor University Medical Center, Dallas, TX; ³Pinnacle Health System, Harrisburg, PA; ⁴Rush University, Chicago, IL; ⁵Transplant Research Institute, Los Angeles, CA; ⁶University of Illinois Chicago, Chicago, IL; ⁷University of Utah Health Science Center, Salt Lake City, UT; ⁸Astellas Pharma Global Development, Northbrook, IL.
Primary objective was to evaluate the efficacy and safety of ASKP1240, antagonistic anti-CD40 antibody, in either a CNI free regimen or a CNI minimization regimen…
2015 American Transplant Congress
Evaluation of the Use of Leflunomide for the Prevention of BK Nephropathy in Renal Transplant Recipients- A Single Center Experience
S. Jonchhe, E. Hollinger, S. Jensik, O. Olaitan, A. Hodowanec, M. Hertl, S. Fayek, E. Chan, C. Pullum, N. Alvey.
Rush University Medical Center, Chicago, IL.
Objective: The purpose of this study was to compare the efficacy of leflunomide in combination with reduced immunosuppression versus reduction of immunosuppression alone for the…
2015 American Transplant Congress
An Investigation of 12 Cases of Membranous Nephropathy of the Donor Origin Accidentally Detected by 0-h Renal Biopsy During Kidney Transplantation
K. Unagami,¹ D. Toki,¹ M. Okumi,¹ H. Ishigooka,¹ K. Tsujimura,¹ T. Kanzawa,¹ K. Omoto,¹ H. Ishida,¹ K. Nitta,² K. Tanabe.¹
¹Urology, Tokyo Women's Medical University, Shinjuku-ku, Tokyo, Japan; ²Nephrology, Tokyo Women's Medical University, Shinjuku-ku, Tokyo, Japan.
Membranous Nephropathy (MN) is a type of glomerulonephritis characterized by thickening of the glomerular basement membrane with immunoglobulin deposition. Proteinuria is a primary symptom, and…
2015 American Transplant Congress
Are AT1R Antibodies as Dangerous as HLA-DSAs in Renal Allografts?
E. Cuevas, J. Arreola-Guerra, E. Hernandez-Mendez, I. Salcedo, M. Vilatoba, A. Contreras, A. Sanchez-Cedillo, J. Ramirez, D. de Rungs, J. Granados, L. Morales-Buenrostro, J. Alberu.
1Transplantation, 1aNephrology-Mineral Metabolism, Inst Nal de Ciencias Medicas y Nutricion SZ, Mexico City, Distrito Federal, Mexico.
Angiotensin II type 1 receptor antibodies (AT1Rab) have been associated with a significantly lower graft survival and a higher risk of acute rejection after kidney…