ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2015 American Transplant Congress

    Comprehensive Study of 3 Nomenclatures to Discriminate CD8 Subsets in Healthy Volunteers and in Kidney Transplant Recipients

    M. Yap,1,3 G. Tilly,1,3 M. Giral,1,2 S. Brouard,1,2 N. Degauque.1,2

    1UMR 1064, INSERM, Nantes, France; 2ITUN, CHU de Nantes, Nantes, France; 3Faculté de Médecine, Université de Nantes, Nantes, France.

    Objective. Historical classification to distinguish central memory (CM), naïve, effector memory (EM), and terminally-differentiated effector memory (TEMRA) CD8 T cells is based on CD45RA and…
  • 2015 American Transplant Congress

    Divergence in Risk Factors for Graft Loss and Death Across Race May Mediate Kidney Transplant Outcome Disparity

    M. Posadas Salas,1 D. Taber,2 M. Kamel,1 M. Kadian,1 M. Salazar,1 P. Mohan,1 T. Srinivas.1

    1Department of Medicine, Medical University of South Carolina, Charleston, SC; 2Department of Surgery, Medical University of South Carolina, Charleston, SC.

    Differences in outcomes between African American and non-African American kidney transplant recipients may reflect disparate access to health care. Minimizing this disparity demands a deeper…
  • 2015 American Transplant Congress

    Non-Invasive Immune Monitoring Assay in Transplant Recipients

    M. Gasser,1 I. Tsaur,2 K. Lopau,1 C. Germer,1 A. Chandraker,3 A. Waaga-Gasser.1

    1Department of Surgery I, University of Wuerzburg, Wuerzburg, Germany; 2Department of Urology, University of Frankfurt, Frankfurt, Germany; 3Transplantation Center, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

    A reliable non-invasive assay of immune responsiveness would help to predict the development of chronic rejection, stable function or tolerance in transplant recipients. Our aim…
  • 2015 American Transplant Congress

    Pharmacokinetics of Everolimus (EVL) in Elderly Recipients Under Low-Tacrolimus(TAC)/Everolimus in the First Year After Renal Transplantation. Data from the NEverOLd Trial

    E. David-Neto,1 P. Romano,2 F. Agena,1 P. Ebner,2 A. Triboni,1 F. Ramos,1 N. Galante,1 F. Lemos.1

    1Renal Transplantation Service, Hospital das Clinicas – University of São Paulo School of Medicine, Sao Paulo, Brazil; 2Division of Central Laboratory, Hospital das Clinicas – University of São Paulo School of Medicine, Sao Paulo, Brazil.

    Elderly ( >60 years) recipients are being renal transplanted more frequently. The pharmacokinetics studies (PK) of immunosuppressive drugs in healthy volunteers, rarely, if ever, include…
  • 2015 American Transplant Congress

    Outcomes of Kidney Transplant Recipients Minimally Immunosuppressed: A Cohort Study Analysis

    A.-H. Querard,1,2,3 F. Gillaizeau,2,1 G. Couvrat-Desvergne,1,2,3 J. Dantal,1,4,5 P. Daguin,1 S. Le Floch,1 S. Castagnet,6 S. Brouard,1,4 Y. Foucher,2,1 M. Giral.1,2,4,5

    1Institute for Transplantation, Urology and Nephrology (ITUN), CHU Nantes, RTRS « Centaure », INSERM U1064, Université de Nantes, Nantes, France; 2EA 4275 SPHERE– Biostatistics, Pharmacoepidemiology and Human Sciences Research, Nantes University, Nantes, France; 3Centre Hospitalier Departemental de Vendée, La Roche sur Yon, France; 4Centre d'Investigation Clinique Biothérapie, Nantes, France; 5Centre Hospitalier Universitaire, Nantes, France; 6HLA Laboratory, Etablissement Français du Sang, Nantes, France.

    Background: Renal transplantation is the treatment of choice for endstage renal disease. Nevertheless, it involves immunosuppressive treatments with Serious Adverse Events (SAE) such as infections…
  • 2015 American Transplant Congress

    Long-Term Follow-Up After Conversion from Twice-Daily Tacrolimus Formulation to Once-Daily Tacrolimus Formulation in Pediatric Kidney Transplantation

    C. Choi, A. Han, S. Min, S.-K. Min, T. Lee, I.-M. Jung, S. Kim, J. Ha.

    Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea.

    PurposeTacrolimus is one of the most frequently used immunosuppressants in pediatric kidney transplantation (KT) as in adult. In Pediatric kidney recipients, it is more important…
  • 2015 American Transplant Congress

    Program-Effect Attenuation With Time Posttransplant

    N. Salkowski,1 L. Hunsicker,1,2 J. Snyder,1 B. Kasiske.1,3

    1Scientific Registry of Transplant Recipients, Minneapolis Medical Research Foundation, Minneapolis, MN; 2Department of Medicine, University of Iowa, College of Medicine, Iowa City, IA; 3Department of Medicine, University of Minnesota, Minneapolis, MN.

    The program-specific reports produced by SRTR include 1-month, 1-year, and 3-year posttransplant graft and patient survival measures. The 1-month and 1-year measures use the same…
  • 2015 American Transplant Congress

    Clinical Subclassifiation of ABMR Phenotypes: Recognizing Variation in Presentation

    P. Halloran, M. Lopez, I. Salazar, J. Chang.

    Alberta Transplant Applied Genomics Centre, Edmonton, Canada.

    The diagnosis of ABMR in kidney transplants is based on ptc-, g- and cg-lesions in biopsies and donor-specific antibody (DSA). To recognize the actual phenotypes…
  • 2015 American Transplant Congress

    The Economic Impact of Nonimmune Complications in Contemporary Kidney Transplantation

    K. Lentine,1 M. Schnitzler,1 D. Axelrod,2 D. Segev,3 D. Brennan,4 J. Tuttle-Newhall,1 H. Xiao,1 L. Kucirka,3 V. Dharnidharka.4

    1Saint Louis Univ, St Louis; 2Dartmouth, Lebanon; 3Johns Hopkins, Baltimore; 4Washington Univ, St. Louis.

    The clinical burden and economic impacts of nonimmune complications after kidney transplant (KT) are incompletely defined.We examined United States Renal System Registry Data for Medicare-insured…
  • 2015 American Transplant Congress

    Assessment of IgG Subclass Significance for Early Graft Rejection and Long-Term Survival in HLA-Antibody Incompatible Renal Transplantation: Multivariate Approach

    N. Khovanova,1 D. Lowe,2 S. Daga,1,3 T. Shaikhina,1 N. Krishnan,3 D. Mitchell,1 D. Zehnder,1 D. Briggs,2 R. Higgins.3

    1University of Warwick, Coventry, United Kingdom; 2NHS Blood and Transplant, Birmingham, United Kingdom; 3University Hospitals Coventry and Warwickshire, Coventry, United Kingdom.

    Donor HLA specific antibodies (DSA) can cause acute rejection and graft lost after renal transplantation. However neither the damaging antibody types, nor their acceptable levels…
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